TcCLB.510747.170

hypothetical protein, conserved
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_146796 OG7: OG7_0002947 151 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 151 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.510609.130 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506265.180 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511741.30 ⚠
replication factor C, subunit 2, putative
— OG7
TcCLB.508647.40 ⚠
replication factor C, subunit 1, putative
— OG7
TcCLB.511589.160 ⚠
replication factor C, subunit 4, putative
— OG7
TcCLB.510737.110 ⚠
replication factor C, subunit 3, putative
— OG7
TcCLB.511435.20 ⚠
Replication Factor C Subunit 1-related protei
— OG7
TcCLB.507929.20 ⚠
co-chaperone GrpE, putative
— OG7
TcCLB.504153.300 ⚠
GTPase protein, putative
— OG7
TcCLB.506287.150 ⚠
GTP-binding protein, putative
— OG7
TcCLB.510609.30 ⚠
GTPase, putative
— OG7
TcCLB.510719.300 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
TcCLB.503489.10 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
TcCLB.505945.20 ⚠
ribonuclease mar1, putative
— OG7
TcCLB.505945.30 ⚠
ribonuclease mar1, putative
— OG7
TcCLB.503479.49 ⚠
U6 snRNA-associated Sm-like protein LSm7p
— OG7
TcCLB.509777.100 ⚠
ubiquitin-activating enzyme, putative
— OG7
TcCLB.506885.416 ⚠
regulator of chromosome condensation (RCC1),
— OG7
TcCLB.506893.25 ⚠
U6 snRNA-associated Sm-like protein LSm6p
— OG7
TcCLB.511585.130 ⚠
ubiquitin activating enzyme, putative
— OG7
TcCLB.509551.64 ⚠
small nuclear ribonucleoprotein Sm-F, putativ
— OG7
TcCLB.510091.70 ⚠
U6 snRNA-associated Sm-like protein LSm8, put
— OG7
TcCLB.509965.30 ⚠
small nuclear ribonucleoprotein Sm-E, putativ
— OG7
TcCLB.510105.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508213.9 ⚠
regulator of chromosome condensation, putativ
— OG7
TcCLB.508439.30 ⚠
regulator of chromosome condensation 1-like p
— OG7
TcCLB.506773.180 ⚠
regulator of chromatin condensation, putative
— OG7
TcCLB.510593.10 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcCLB.508211.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510761.70 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.508277.360 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.506745.4 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcCLB.506743.220 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510601.30 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
TcCLB.505843.10 ⚠
glutamate dehydrogenase, putative
— OG7
TcCLB.509445.39 ⚠
glutamate dehydrogenase, putative
— OG7
TcCLB.506457.130 ⚠
Domain of unknown function (DUF4042), putativ
— OG7
TcCLB.506859.70 ⚠
guide RNA associated protein, GAP2, putative
— OG7
TcCLB.509153.110 ⚠
hypothetical protein
— OG7
TcCLB.510377.61 ⚠
UEV domain/Zinc finger, C3HC4 type (RING fing
— OG7
TcCLB.511127.350 ⚠
Plus-3 domain/Zinc finger, C3HC4 type (RING f
— OG7
TcCLB.510769.70 ⚠
hypothetical protein
— OG7
TcCLB.506945.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511729.9 ⚠
calmodulin, putative (fragment)
— OG7
TcCLB.507809.110 ⚠
WD domain, G-beta repeat, putative
— OG7
TcCLB.503959.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511751.180 ⚠
pseudouridine synthase A-like protein, putati
— OG7
TcCLB.503579.110 ⚠
pseudouridylate synthase I, putative
— OG7
TcCLB.511429.20 ⚠
cyclophilin 15, putative
— OG7
TcCLB.506755.279 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.