TcCLB.508647.40

replication factor C, subunit 1, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_101059 OG7: OG7_0001167 109 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:
Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 109 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.511353.40 ⚠
eukaryotic translation initiation factor 4E (
— OG7
TcCLB.507395.14 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504147.190 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507929.20 ⚠
co-chaperone GrpE, putative
— OG7
TcCLB.511589.160 ⚠
replication factor C, subunit 4, putative
— OG7
TcCLB.510737.110 ⚠
replication factor C, subunit 3, putative
— OG7
TcCLB.508465.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510759.200 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506127.170 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
TcCLB.506941.260 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511911.21 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510777.20 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.508277.180 ⚠
mismatch repair protein MSH3, putative
— OG7
TcCLB.503525.20 ⚠
Cyclin 12, L-type
— OG7
TcCLB.508539.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506289.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506893.25 ⚠
U6 snRNA-associated Sm-like protein LSm6p
— OG7
TcCLB.510747.170 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507011.250 ⚠
Putative death-receptor fusion protein (DUF24
— OG7
TcCLB.503821.10 ⚠
RNA-binding protein RBP10, putative, DNA-dire
— OG7
TcCLB.503651.4 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcCLB.509551.64 ⚠
small nuclear ribonucleoprotein Sm-F, putativ
— OG7
TcCLB.510091.70 ⚠
U6 snRNA-associated Sm-like protein LSm8, put
— OG7
TcCLB.509965.30 ⚠
small nuclear ribonucleoprotein Sm-E, putativ
— OG7
TcCLB.503479.70 ⚠
hook complex protein, conserved
— OG7
TcCLB.511737.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509967.30 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.507841.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507527.20 ⚠
Centrosomal protein of 164 kDa, putative
— OG7
TcCLB.506503.120 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509153.110 ⚠
hypothetical protein
— OG7
TcCLB.508995.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510105.9 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcCLB.511577.160 ⚠
kinetoplastid kinetochore protein 18
— OG7
TcCLB.510859.50 ⚠
Domain of unknown function (DUF3437), putativ
— OG7
TcCLB.510861.14 ⚠
Domain of unknown function (DUF3437), putativ
— OG7
TcCLB.506829.50 ⚠
Ring finger domain/Zn-finger in ubiquitin-hyd
— OG7
TcCLB.506249.20 ⚠
protein transport protein Sec23A, putative
— OG7
TcCLB.506753.90 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507797.9 ⚠
nuclear transcription factor, putative
— OG7
TcCLB.503953.50 ⚠
Beta-lactamase superfamily domain containing
— OG7
TcCLB.511305.20 ⚠
Centrosomal protein of 164 kDa, putative
— OG7
TcCLB.508237.9 ⚠
protein kinase, putative
— OG7
TcCLB.511435.20 ⚠
Replication Factor C Subunit 1-related protei
— OG7
TcCLB.509453.40 ⚠
DNA-directed RNA polymerase I subunit RPB10,
— OG7
TcCLB.510757.9 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcCLB.511435.30 ⚠
MORN repeat-containing protein
— OG7
TcCLB.510749.4 ⚠
ubiquitin-protein ligase, putative
— OG7
TcCLB.509597.4 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511585.130 ⚠
ubiquitin activating enzyme, putative
— OG7
Page 1 of 3
Next →
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.