TcCLB.511315.9

ATP-dependent RNA helicase, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_100305 OG7: OG7_0001850 137 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:
Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 137 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.503813.20 ⚠
hypothetical protein, conserved
— Both
TcCLB.511075.40 ⚠
cullin, putative
— OG7
TcCLB.510599.14 ⚠
acetyl-CoA carboxylase (fragment)
— Both
TcCLB.503637.20 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
TcCLB.510105.40 ⚠
cullin-like protein, putative
— OG7
TcCLB.510557.50 ⚠
mucin TcMUCII, putative
— OG6
TcCLB.511217.100 ⚠
cullin 3, putative
— OG7
TcCLB.508369.50 ⚠
acetyl-CoA carboxylase (fragment)
— Both
TcCLB.511803.10 ⚠
cullin 2, putative
— OG7
TcCLB.507395.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504449.30 ⚠
hypothetical protein, conserved
— Both
TcCLB.509967.189 ⚠
kinesin, putative (fragment)
— Both
TcCLB.503513.40 ⚠
proteasome regulatory non-ATPase subunit 6, p
— Both
TcCLB.511047.50 ⚠
proteasome regulatory ATPase subunit 2, putat
— +3 more Both
TcCLB.507809.30 ⚠
ribose-phosphate pyrophosphokinase, putative
— Both
TcCLB.509267.50 ⚠
U5 small nuclear ribonucleoprotein component,
— Both
TcCLB.507813.10 ⚠
structural maintenance of chromosome 3 protei
— Both
TcCLB.503531.49 ⚠
structural maintenance of chromosome 3, putat
— Both
TcCLB.504147.200 ⚠
19S proteasome regulatory subunit, Regulatory
— +3 more Both
TcCLB.511365.10 ⚠
hypothetical protein, conserved
— Both
TcCLB.511527.9 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— Both
TcCLB.398751.10 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— Both
TcCLB.503777.19 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcCLB.506607.19 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcCLB.510431.250 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcCLB.508717.30 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcCLB.503897.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504159.80 ⚠
histone deacetylase, putative
— OG7
TcCLB.506221.30 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.420989.10 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.509011.20 ⚠
RNA polymerase IIA largest subunit, putative
— OG7
TcCLB.507641.14 ⚠
neurobeachin/beige protein, putative
— OG7
TcCLB.506659.39 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.509951.49 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
TcCLB.509151.80 ⚠
SpoU rRNA Methylase family, putative
— OG7
TcCLB.510755.19 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504137.60 ⚠
beta adaptin, putative
— OG7
TcCLB.508779.90 ⚠
structural maintenance of chromosome protein
— OG7
TcCLB.509965.350 ⚠
ubiquitin-protein ligase, putative
— OG7
TcCLB.506223.80 ⚠
Metalloprotease M41 FtsH, putative
— +2 more OG7
TcCLB.511115.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504883.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511625.40 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.507875.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507213.10 ⚠
hypothetical protein, conserved
— +2 more OG7
TcCLB.507739.20 ⚠
mitochondrial ATP-dependent zinc metallopepti
— +2 more OG7
TcCLB.510105.210 ⚠
mitochondrial ATP-dependent zinc metallopepti
— +2 more OG7
TcCLB.510963.90 ⚠
elongation factor 2, putative
— OG7
TcCLB.508169.20 ⚠
elongation factor 2, putative
— OG7
TcCLB.504077.40 ⚠
translation elongation factor EF-2, putative
— OG7
Page 1 of 3
Next →
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.