TcCLB.511527.9

SPRY domain/HECT-domain (ubiquitin-transferase), putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_147203 OG7: OG7_0031172 82 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 82 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.509625.10 ⚠
ATP-dependent RNA helicase, putative (fragmen
— Both
TcCLB.510105.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506635.40 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcCLB.507809.119 ⚠
Autophagy protein Apg6, putative
— OG7
TcCLB.507735.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510159.19 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcCLB.510161.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508837.170 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507511.10 ⚠
cleavage and polyadenylation specificity fact
— Both
TcCLB.507509.89 ⚠
cleavage and polyadenylation specificity fact
— Both
TcCLB.506755.160 ⚠
AAA ATPase, putative
— Both
TcCLB.508439.30 ⚠
regulator of chromosome condensation 1-like p
— OG7
TcCLB.511365.10 ⚠
hypothetical protein, conserved
— Both
TcCLB.510855.40 ⚠
proteasome regulatory non-ATPase subunit, put
— Both
TcCLB.511365.70 ⚠
proteasome regulatory non-ATP-ase subunit 9,
— Both
TcCLB.511315.9 ⚠
ATP-dependent RNA helicase, putative
— Both
TcCLB.506179.59 ⚠
ATP-dependent RNA helicase, putative (fragmen
— Both
TcCLB.511313.40 ⚠
ATP-dependent RNA helicase, putative
— Both
TcCLB.506637.10 ⚠
hypothetical protein, conserved
— Both
TcCLB.509649.30 ⚠
19S proteasome non-atpase subunit 8
— Both
TcCLB.507603.200 ⚠
proteasome regulatory ATPase subunit 3, putat
— +3 more Both
TcCLB.506563.160 ⚠
Raptor N-terminal CASPase like domain contain
— OG7
TcCLB.510105.120 ⚠
protein kinase, putative
— OG7
TcCLB.509769.70 ⚠
DNA polymerase theta (helicase domain only),
— OG7
TcCLB.504051.20 ⚠
ATP-dependent DNA DEAD/DEAH box helicase, put
— OG7
TcCLB.504835.29 ⚠
Flagellum attachment zone protein 14
— OG7
TcCLB.507389.10 ⚠
Flagellum attachment zone protein 14
— OG7
TcCLB.506227.150 ⚠
protein kinase A regulatory subunit
— OG7
TcCLB.510879.50 ⚠
regulatory subunit of protein kinase a-like p
— OG7
TcCLB.507035.110 ⚠
cAMP response protein 1, putative
— OG7
TcCLB.503885.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509073.119 ⚠
proteasome regulatory non-ATP-ase subunit 7,
— Both
TcCLB.506223.80 ⚠
Metalloprotease M41 FtsH, putative
— +2 more OG7
TcCLB.510105.210 ⚠
mitochondrial ATP-dependent zinc metallopepti
— +2 more OG7
TcCLB.507739.20 ⚠
mitochondrial ATP-dependent zinc metallopepti
— +2 more OG7
TcCLB.507213.10 ⚠
hypothetical protein, conserved
— +2 more OG7
TcCLB.510611.40 ⚠
Ankyrin repeats (3 copies), putative
— OG7
TcCLB.503557.20 ⚠
ankyrin repeat protein, putative
— OG7
TcCLB.508489.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510593.10 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcCLB.506773.180 ⚠
regulator of chromatin condensation, putative
— OG7
TcCLB.508387.90 ⚠
paraflagellar rod protein, putative
— Both
TcCLB.506501.290 ⚠
Mucin-associated surface protein (MASP), subg
— OG6
TcCLB.510351.80 ⚠
Pre-mRNA polyadenylation factor FIP1
— Both
TcCLB.503697.9 ⚠
proteasome regulatory non-ATPase subunit 11,
— Both
TcCLB.509489.29 ⚠
proteasome regulatory non-ATP-ase subunit, pu
— Both
TcCLB.504033.180 ⚠
hypothetical protein, conserved
— Both
TcCLB.511585.30 ⚠
hypothetical protein, conserved
— Both
TcCLB.506859.20 ⚠
proteasome regulatory ATPase subunit 5, putat
— +3 more Both
TcCLB.506857.90 ⚠
proteasome regulatory ATPase subunit 1, putat
— +3 more Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.