TcCLB.510773.9

Thioredoxin-like/Protein of unknown function (DUF3638)/Protein of unknown function (DUF3645), putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_111983 OG7: OG7_0009773 184 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 184 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.503989.60 ⚠
protein phosphatase 2C, putative (fragment)
— OG7
TcCLB.510291.30 ⚠
protein phosphatase 2C-like, putative
— OG7
TcCLB.509767.180 ⚠
exosome component CSL4, putative
— Both
TcCLB.506357.130 ⚠
hypothetical protein, conserved
— +2 more Both
TcCLB.511625.40 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.509007.70 ⚠
protein phosphatase 2C, putative
— Both
TcCLB.506925.150 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.506739.200 ⚠
pyruvate dehydrogenase phosphatase
— Both
TcCLB.508131.19 ⚠
Glycosyl hydrolase family 65 central catalyti
— Both
TcCLB.506659.39 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.420989.10 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.506221.30 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.507445.50 ⚠
myosin heavy chain, putative
— OG7
TcCLB.410961.10 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcCLB.506223.120 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
TcCLB.507757.70 ⚠
dihydrolipoamide dehydrogenase, putative, ace
— OG7
TcCLB.510409.39 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
TcCLB.510293.40 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
TcCLB.511435.49 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
TcCLB.506533.34 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcCLB.504137.60 ⚠
beta adaptin, putative
— OG7
TcCLB.511313.30 ⚠
formin, putative
— OG7
TcCLB.509151.80 ⚠
SpoU rRNA Methylase family, putative
— OG7
TcCLB.509379.10 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
TcCLB.506779.60 ⚠
DNA-direcetd RNA polymerase II, subunit 9, pu
— OG7
TcCLB.511417.40 ⚠
DNA-directed RNA polymerase III, putative
— OG7
TcCLB.509951.49 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
TcCLB.504643.49 ⚠
hypothetical protein, conserved (fragment)
— Both
TcCLB.506525.162 ⚠
Flagellum attachment zone protein 9 (fragment
— Both
TcCLB.447255.4 ⚠
ubiquitin, putative
— Both
TcCLB.506527.4 ⚠
Flagellum attachment zone protein 9 (fragment
— Both
TcCLB.506633.100 ⚠
hypothetical protein, conserved
— Both
TcCLB.510599.14 ⚠
acetyl-CoA carboxylase (fragment)
— Both
TcCLB.507547.50 ⚠
hypothetical protein, conserved
— Both
TcCLB.510283.114 ⚠
DNA-directed RNA polymerase I subunit, putati
— Both
TcCLB.509537.50 ⚠
Flagellar Member 1
— Both
TcCLB.509067.40 ⚠
NADH dehydrogenase subunit NI8M, putative
— Both
TcCLB.506673.60 ⚠
Adaptor protein complex AP-3 subunit beta-3
— Both
TcCLB.511545.100 ⚠
RNA methyltransferase, putative
— Both
TcCLB.506947.40 ⚠
peroxisome assembly protein, putative
— OG7
TcCLB.511745.20 ⚠
AAA ATPase, putative
— OG7
TcCLB.510101.150 ⚠
adaptin-related protein-like, putative
— OG7
TcCLB.507837.90 ⚠
cell division cycle protein, putative
— OG7
TcCLB.505989.74 ⚠
peroxisome biogenesis factor 1, putative
— OG7
TcCLB.507093.210 ⚠
myosin heavy chain, putative
— OG7
TcCLB.506925.410 ⚠
ATPase, putative
— OG7
TcCLB.503971.10 ⚠
2OG-Fe(II) oxygenase superfamily, putative
— Both
TcCLB.507739.110 ⚠
myosin IB heavy chain, putative
— OG7
TcCLB.509831.5 ⚠
vesicular transport protein (CDC48 homologue)
— OG7
TcCLB.506367.180 ⚠
vesicular transport protein (CDC48 homologue)
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.