TcCLB.506367.180

vesicular transport protein (CDC48 homologue), putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_102053 OG7: OG7_0001162 53 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 53 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.510599.14 ⚠
acetyl-CoA carboxylase (fragment)
— OG7
TcCLB.506659.39 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.506925.150 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.503989.60 ⚠
protein phosphatase 2C, putative (fragment)
— OG7
TcCLB.506739.200 ⚠
pyruvate dehydrogenase phosphatase
— OG7
TcCLB.510291.30 ⚠
protein phosphatase 2C-like, putative
— OG7
TcCLB.511625.40 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.509767.180 ⚠
exosome component CSL4, putative
— OG7
TcCLB.507923.20 ⚠
U3 small nuclear ribonucleoprotein (snRNP), p
— OG7
TcCLB.511753.130 ⚠
U3 small nuclear ribonucleoprotein (snRNP), p
— OG7
TcCLB.506925.510 ⚠
ribosome production factor 1, putative
— OG7
TcCLB.506925.410 ⚠
ATPase, putative
— OG7
TcCLB.507809.30 ⚠
ribose-phosphate pyrophosphokinase, putative
— OG7
TcCLB.503777.19 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcCLB.509007.70 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.506947.40 ⚠
peroxisome assembly protein, putative
— OG7
TcCLB.505989.74 ⚠
peroxisome biogenesis factor 1, putative
— OG7
TcCLB.508369.50 ⚠
acetyl-CoA carboxylase (fragment)
— OG7
TcCLB.507837.90 ⚠
cell division cycle protein, putative
— OG7
TcCLB.506607.19 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcCLB.503903.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510431.250 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcCLB.508387.160 ⚠
Phosphatidylinositol 4-phosphate 5-kinase, pu
— OG7
TcCLB.508717.30 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcCLB.511745.20 ⚠
AAA ATPase, putative
— OG7
TcCLB.509831.5 ⚠
vesicular transport protein (CDC48 homologue)
— OG7
TcCLB.507611.340 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506357.130 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510771.9 ⚠
Thioredoxin-like/Protein of unknown function
— OG7
TcCLB.510773.9 ⚠
Thioredoxin-like/Protein of unknown function
— OG7
TcCLB.509233.120 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504867.20 ⚠
ABC transporter, putative
— OG7
TcCLB.503789.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510431.160 ⚠
nucleolar GTP-binding protein 1, putative
— OG7
TcCLB.506775.14 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507739.110 ⚠
myosin IB heavy chain, putative
— OG7
TcCLB.504103.30 ⚠
myosin heavy chain, putative
— OG7
TcCLB.507811.120 ⚠
myosin heavy chain MYA2-related, putative
— OG7
TcCLB.511537.69 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507093.210 ⚠
myosin heavy chain, putative
— OG7
TcCLB.508131.19 ⚠
Glycosyl hydrolase family 65 central catalyti
— OG7
TcCLB.504867.120 ⚠
hypothetical protein
— OG7
TcCLB.506755.20 ⚠
paraflagellar rod component, putative
— OG7
TcCLB.507445.50 ⚠
myosin heavy chain, putative
— OG7
TcCLB.506779.190 ⚠
Unconventional myosin
— OG7
TcCLB.503905.10 ⚠
myosin heavy chain, putative
— OG7
TcCLB.510075.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511539.9 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509497.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511527.70 ⚠
Unconventional myosin
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.