TcCLB.507257.60

Fumarate hydratase class I, cytosolic
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_102839 OG7: OG7_0008166 34 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 34 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.503855.30 ⚠
adenylosuccinate lyase, putative
— Both
TcCLB.506529.430 ⚠
alanine aminotransferase, putative, glutamic-
— Both
TcCLB.510737.10 ⚠
6-phosphogluconate dehydrogenase, decarboxyla
— Both
TcCLB.506605.170 ⚠
inosine-guanine nucleoside hydrolase, putativ
— Both
TcCLB.506945.160 ⚠
S-adenosylmethionine synthetase, putative
— Both
TcCLB.511067.30 ⚠
transketolase, putative
— Both
TcCLB.506943.4 ⚠
aldehyde dehydrogenase, putative
— Both
TcCLB.506885.413 ⚠
glyceraldehyde-3-phosphate dehydrogenase, put
— Both
TcCLB.507669.10 ⚠
fumarate hydratase, putative
— Both
TcCLB.506529.420 ⚠
glutamic--pyruvic transaminase, putative, ala
— Both
TcCLB.507011.269 ⚠
6-phosphogluconate dehydrogenase, decarboxyla
— Both
TcCLB.504431.100 ⚠
guanine deaminase, putative
— Both
TcCLB.505843.10 ⚠
glutamate dehydrogenase, putative
— Both
TcCLB.509445.39 ⚠
glutamate dehydrogenase, putative
— Both
TcCLB.508387.20 ⚠
methylthioadenosine phosphorylase, putative
— Both
TcCLB.511069.4 ⚠
transketolase, putative
— Both
TcCLB.511733.10 ⚠
aldehyde dehydrogenase, putative
— Both
TcCLB.461165.16 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— Both
TcCLB.508647.270 ⚠
malic enzyme, putative
— Both
TcCLB.509801.30 ⚠
citrate synthase, putative
— Both
TcCLB.508647.280 ⚠
malic enzyme
— Both
TcCLB.510741.10 ⚠
cystathione gamma lyase, putative
— Both
TcCLB.511211.60 ⚠
Serine/threonine-protein phosphatase 2A, puta
— OG6
TcCLB.507641.60 ⚠
aldehyde dehydrogenase, putative
— Both
TcCLB.511537.40 ⚠
protein phosphatase 4, putative
— OG6
TcCLB.510739.19 ⚠
cystathione gamma lyase, putative (fragment)
— Both
TcCLB.508731.60 ⚠
adenylosuccinate synthetase, putative
— Both
TcCLB.506943.50 ⚠
glyceraldehyde 3-phosphate dehydrogenase, put
— Both
TcCLB.508537.10 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— Both
TcCLB.510105.230 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— Both
TcCLB.506943.60 ⚠
glyceraldehyde 3-phosphate dehydrogenase, put
— Both
TcCLB.506409.240 ⚠
glyceraldehyde 3-phosphate dehydrogenase, C-t
— Both
TcCLB.504507.5 ⚠
trypanothione reductase, putative (fragment)
— Both
TcCLB.484299.10 ⚠
trypanothione reductase, putative
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.