TcCLB.503405.10

glutamine synthetase
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_100668 OG7: OG7_0003785 78 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 78 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.503589.10
GDP-mannose pyrophosphorylase
— Both
TcCLB.436535.19 ⚠
Glucose-6-phosphate dehydrogenase, putative
— Both
TcCLB.439653.10 ⚠
NADH-dependent fumarate reductase, putative
— OG6
TcCLB.503841.80 ⚠
NADH-dependent fumarate reductase, putative
— Both
TcCLB.503467.9 ⚠
NADH-dependent fumarate reductase, putative (
— Both
TcCLB.510215.10 ⚠
NADH-dependent fumarate reductase, putative
— Both
TcCLB.510213.110 ⚠
NADH-dependent fumarate reductase, putative
— Both
TcCLB.506493.60
hypothetical protein, conserved
— Both
TcCLB.507739.90
hypothetical protein, conserved
— Both
TcCLB.510719.310
hypothetical protein, conserved
— Both
TcCLB.503955.20 ⚠
mitochondrial DNA polymerase beta, putative
— Both
TcCLB.506953.49 ⚠
glucose-6-phosphate 1-dehydrogenase, glucose-
— Both
TcCLB.508535.10 ⚠
NADH-dependent fumarate reductase, putative
— Both
TcCLB.510181.9 ⚠
inositol-3-phosphate synthase, putative (frag
— Both
TcCLB.503639.10 ⚠
inositol-3-phosphate synthase, putative
— Both
TcCLB.510101.140
pyruvate phosphate dikinase, putative
— Both
TcCLB.509965.340
hypothetical protein, conserved
— Both
TcCLB.510101.200
zinc finger ccch and cchc domain-containing p
— Both
TcCLB.511555.60
ubiquitin ligase, putative
— Both
TcCLB.510963.39
PUB domain containing protein, putative
— Both
TcCLB.506127.30 ⚠
phenylalanyl-tRNA synthetase, putative
— Both
TcCLB.506885.413 ⚠
glyceraldehyde-3-phosphate dehydrogenase, put
— OG7
TcCLB.509967.30 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.510777.20 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcCLB.511911.21 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511801.10 ⚠
leucine rich repeat
— OG7
TcCLB.509757.20 ⚠
leucine carboxyl methyltransferase, putative
— OG7
TcCLB.507669.14 ⚠
hypothetical protein, conserved
— OG7
TcCLB.449247.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508205.4 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510073.50 ⚠
elongation factor 1-gamma (EF-1-gamma), putat
— OG7
TcCLB.508125.100 ⚠
mucin TcMUCII, putative
— OG6
TcCLB.503953.59 ⚠
mitochondrial DNA polymerase beta-PAK, putati
— OG7
TcCLB.503955.10 ⚠
mitochondrial DNA polymerase beta-PAK, putati
— OG7
TcCLB.503749.10 ⚠
Serine hydrolase (FSH1)/RWD domain/50S riboso
— OG7
TcCLB.509099.10 ⚠
GTP-binding protein, putative
— OG7
TcCLB.511731.60 ⚠
glutamyl-tRNA synthetase, putative
— OG7
TcCLB.511625.50 ⚠
GTP-binding protein, putative
— Both
TcCLB.506857.30
hypothetical protein, conserved
— Both
TcCLB.504153.360
succinyl-coA:3-ketoacid-coenzyme A transferas
— Both
TcCLB.510739.19 ⚠
cystathione gamma lyase, putative (fragment)
— Both
TcCLB.511613.100 ⚠
elongation factor 1-gamma (EF-1-gamma), putat
— Both
TcCLB.422507.10 ⚠
glycine dehydrogenase [decarboxylating], puta
— Both
TcCLB.510911.50 ⚠
glycine cleavage system P-protein, putative,
— Both
TcCLB.506409.240 ⚠
glyceraldehyde 3-phosphate dehydrogenase, C-t
— Both
TcCLB.506943.60 ⚠
glyceraldehyde 3-phosphate dehydrogenase, put
— Both
TcCLB.510105.230 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— Both
TcCLB.508537.10 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— Both
TcCLB.506943.50 ⚠
glyceraldehyde 3-phosphate dehydrogenase, put
— Both
TcCLB.461165.16 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— Both
Page 1 of 2
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.