TcCLB.436535.19

Glucose-6-phosphate dehydrogenase, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_100726 OG7: OG7_0003663 24 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 24 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.506553.20 ⚠
bromodomain factor 2 protein
— +4 more Both
TcCLB.510719.70 ⚠
bromodomain-containing protein 3
— OG7
TcCLB.511731.60 ⚠
glutamyl-tRNA synthetase, putative
— OG7
TcCLB.506953.49 ⚠
glucose-6-phosphate 1-dehydrogenase, glucose-
— +2 more Both
TcCLB.506493.60 ⚠
hypothetical protein, conserved
— Both
TcCLB.511589.200 ⚠
S-adenosylhomocysteine hydrolase, putative
— Both
TcCLB.503589.10 ⚠
GDP-mannose pyrophosphorylase
— Both
TcCLB.510101.140 ⚠
pyruvate phosphate dikinase, putative
— Both
TcCLB.510181.9 ⚠
inositol-3-phosphate synthase, putative (frag
— Both
TcCLB.508277.160 ⚠
glutaminyl-tRNA synthetase, putative
— Both
TcCLB.422507.10 ⚠
glycine dehydrogenase [decarboxylating], puta
— Both
TcCLB.507641.60 ⚠
aldehyde dehydrogenase, putative
— Both
TcCLB.510911.50 ⚠
glycine cleavage system P-protein, putative,
— Both
TcCLB.503639.10 ⚠
inositol-3-phosphate synthase, putative
— Both
TcCLB.509829.20 ⚠
isovaleryl-coA dehydrogenase, putative
— Both
TcCLB.506367.10 ⚠
isovaleryl-coA dehydrogenase, putative (fragm
— Both
TcCLB.503405.10 ⚠
glutamine synthetase
— Both
TcCLB.511407.60 ⚠
small GTP-binding protein Rab11
— OG6
TcCLB.504163.40 ⚠
fructose-bisphosphate aldolase, glycosomal, p
— Both
TcCLB.504163.50 ⚠
fructose-bisphosphate aldolase, glycosomal, p
— Both
TcCLB.508375.60 ⚠
succinate dehydrogenase subunit
— +2 more Both
TcCLB.507091.30 ⚠
succinate dehydrogenase subunit
— +2 more Both
TcCLB.507625.150 ⚠
hypothetical protein, conserved
— +2 more Both
TcCLB.508805.20 ⚠
Degradation arginine-rich protein for mis-fol
— +2 more Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.