TcCLB.511555.110

Domain of unknown function (DUF4486), putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_389593 OG7: OG7_0009578 50 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 50 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.511627.140
hypothetical protein, conserved
— OG7
TcCLB.511001.130
hypothetical protein, conserved
— OG7
TcCLB.510089.200
Eukaryotic translation initiation factor 3 su
— OG7
TcCLB.507011.60 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
TcCLB.507669.14 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506529.220
hypothetical protein, conserved
— OG7
TcCLB.509067.50
hypothetical protein, conserved
— OG7
TcCLB.507507.30
Bardet-Biedl syndrome 9 protein
— OG7
TcCLB.507237.110 ⚠
elongation factor 1-gamma (EF-1-gamma), putat
— OG7
TcCLB.511363.4
hypothetical protein, conserved
— OG7
TcCLB.506773.40
3-methylcrotonoyl-CoA carboxylase beta subuni
— OG7
TcCLB.506529.490
hypothetical protein, conserved
— OG7
TcCLB.511429.10 ⚠
transmembrane protein, conserved (fragment)
— OG7
TcCLB.509979.40
Zn-finger in Ran binding protein and others/S
— OG7
TcCLB.511801.10 ⚠
leucine rich repeat
— OG7
TcCLB.510105.120
protein kinase, putative
— OG7
TcCLB.511753.30
kinesin, putative
— OG7
TcCLB.510163.20 ⚠
elongation factor 1-gamma (EF-1-gamma), putat
— OG7
TcCLB.506811.150
hypothetical protein, conserved
— OG7
TcCLB.504247.79 ⚠
transmembrane protein, conserved (fragment)
— OG7
TcCLB.503531.49 ⚠
structural maintenance of chromosome 3, putat
— OG7
TcCLB.508307.44
pre-mRNA splicing factor 46, putative
— OG7
TcCLB.506599.10 ⚠
elongation factor 1-gamma (EF-1-gamma), putat
— OG7
TcCLB.508265.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508181.10
hypothetical protein, conserved
— OG7
TcCLB.510101.350
hypothetical protein, conserved
— OG7
TcCLB.508723.70
AAA domain containing protein, putative
— OG7
TcCLB.508205.4 ⚠
hypothetical protein, conserved
— OG7
TcCLB.449247.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510275.180 ⚠
elongation factor 1-gamma (EF-1-gamma), putat
— OG7
TcCLB.510073.50 ⚠
elongation factor 1-gamma (EF-1-gamma), putat
— OG7
TcCLB.506603.50 ⚠
elongation factor 1-gamma (EF-1-gamma), putat
— OG7
TcCLB.508779.90 ⚠
structural maintenance of chromosome protein
— OG7
TcCLB.507813.10 ⚠
structural maintenance of chromosome 3 protei
— OG7
TcCLB.508321.40
Tripartite attachment complex protein 102
— OG7
TcCLB.511211.20
Coatomer subunit gamma
— OG7
TcCLB.506941.194
hypothetical protein, conserved
— OG7
TcCLB.508163.150 ⚠
elongation factor 1-gamma (EF-1-gamma), putat
— OG7
TcCLB.507809.119
Autophagy protein Apg6, putative
— OG7
TcCLB.503977.79 ⚠
elongation factor 1-gamma (EF-1-gamma), putat
— OG7
TcCLB.503811.70
bardet-biedl syndrome 7 protein
— OG7
TcCLB.506563.30
coatomer beta subunit, putative
— OG7
TcCLB.510405.9 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcCLB.507671.30
25 kDa translation elongation factor 1-beta
— OG7
TcCLB.508165.170
Mucin-associated surface protein (MASP), subg
— OG7
TcCLB.511613.100 ⚠
elongation factor 1-gamma (EF-1-gamma), putat
— OG7
TcCLB.405165.19 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcCLB.507611.340
hypothetical protein, conserved
— OG7
TcCLB.506925.220
hypothetical protein, conserved
— OG7
TcCLB.507611.310
eukaryotic translation initiation factor 3 su
— OG7
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.