TcCLB.503697.120

hypothetical protein, conserved
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6r21_106764 OG7: OG7_0166793 17 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 17 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.503449.30
clathrin coat assembly protein, putative
— Both
TcCLB.511353.40 ⚠
eukaryotic translation initiation factor 4E (
— OG7
TcCLB.421959.10 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
TcCLB.506127.170 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
TcCLB.504935.10 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
TcCLB.510777.29 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
TcCLB.508569.130 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
TcCLB.508181.20 ⚠
6-phosphofructo-2-kinase 1
— OG7
TcCLB.510963.50 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
TcCLB.510167.29
ribosomal RNA processing protein 4, putative,
— Both
TcCLB.508207.230 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— Both
TcCLB.506025.50
Vacuolar proton pump subunit B, putative
— Both
TcCLB.503893.150
Right handed beta helix region/Periplasmic co
— Both
TcCLB.508307.70
hypothetical protein, conserved
— Both
TcCLB.506359.90
hypothetical protein, conserved
— Both
TcCLB.508089.60
mRNA capping enzyme, beta chain, putative
— Both
TcCLB.507641.230
hypothetical protein, conserved
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.