TcCLB.507603.30

PITH domain-containing protein
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_102988 OG7: OG7_0006444 182 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 182 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.508729.18 ⚠
Sucrase/ferredoxin-like, putative
— Both
TcCLB.506931.10 ⚠
haloacid dehalogenase-like hydrolase, putativ
— +1 more Both
TcCLB.511041.4 ⚠
Sucrase/ferredoxin-like, putative
— Both
TcCLB.506779.170 ⚠
haloacid dehalogenase hydrolase, putative
— OG7
TcCLB.509099.10 ⚠
GTP-binding protein, putative
— OG7
TcCLB.510719.60
Biotin--acetyl-CoA-carboxylase ligase, putati
— Both
TcCLB.506635.60
pyroglutamyl-peptidase I, putative
— Both
TcCLB.509757.30 ⚠
stress-inducible protein STI1-like, putative
— Both
TcCLB.511545.120 ⚠
superoxide dismutase, putative
— Both
TcCLB.503989.60 ⚠
protein phosphatase 2C, putative (fragment)
— Both
TcCLB.510861.140 ⚠
CAMK/CAMKL family protein kinase, putative
— Both
TcCLB.511589.140
PEP mutase, putative, phosphoenolpyruvate mut
— Both
TcCLB.506925.319 ⚠
isocitrate dehydrogenase, putative
— Both
TcCLB.510291.30 ⚠
protein phosphatase 2C-like, putative
— Both
TcCLB.510143.40
UBX domain-containing protein
— Both
TcCLB.511627.100 ⚠
TPR-repeat protein, putative
— Both
TcCLB.509775.40 ⚠
iron superoxide dismutase A, mitochondrial
— Both
TcCLB.464807.10 ⚠
serine/threonine protein kinase, putative, CA
— Both
TcCLB.506221.30 ⚠
protein phosphatase 2C, putative
— Both
TcCLB.509475.10 ⚠
mitogen-activated protein kinase 3, putative
— OG6
TcCLB.503713.30
6-phosphogluconolactonase, putative
— Both
TcCLB.503805.10 ⚠
Mitochondrial Editosome-like Complex TUTase
— Both
TcCLB.507039.10 ⚠
iron superoxide dismutase, putative
— Both
TcCLB.506677.39 ⚠
Elongation factor G1, mitochondrial, putative
— Both
TcCLB.511303.34
Macro domain containing protein, putative
— Both
TcCLB.507809.60
hypothetical protein, conserved
— Both
TcCLB.505945.5 ⚠
mitogen-activated protein kinase 3, putative
— OG6
TcCLB.511575.60 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— Both
TcCLB.511573.40
Mitogen-activated protein kinase 10, putative
— OG6
TcCLB.508373.20 ⚠
dihydroorotase, putative
— Both
TcCLB.506591.20
U-box domain protein, putative
— Both
TcCLB.503425.20 ⚠
monothiol glutaredoxin, putative
— Both
TcCLB.511625.40 ⚠
protein phosphatase 2C, putative
— Both
TcCLB.511179.100 ⚠
monothiol glutaredoxin, putative
— Both
TcCLB.507941.100
hypothetical protein, conserved
— Both
TcCLB.510323.20
Flagellum attachment zone protein 19, putativ
— Both
TcCLB.511801.50
tRNA threonylcarbamoyl adenosine modification
— Both
TcCLB.511577.40
35 kDa cyclophilin, putative, rotamase, putat
— OG6
TcCLB.503893.60 ⚠
UBA/TS-N domain containing protein, putative
— Both
TcCLB.503697.110
Soluble NSF attachment protein, SNAP, putativ
— Both
TcCLB.508181.140 ⚠
inorganic pyrophosphatase, putative
— Both
TcCLB.503613.60 ⚠
acidocalcisomal pyrophosphatase, putative
— Both
TcCLB.506895.40 ⚠
Kinesin-13 1, putative
— OG7
TcCLB.509589.30 ⚠
Kinesin-13 5, putative
— OG7
TcCLB.508921.30 ⚠
Kinesin-13 4, putative
— OG7
TcCLB.505123.28 ⚠
Kinesin-13 4, putative
— OG7
TcCLB.510841.10 ⚠
Kinesin-13 4b, putative (fragment)
— OG7
TcCLB.509073.30 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.510749.40 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
TcCLB.511801.14 ⚠
protein lipid droplet kinase (LDK)
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.