TcCLB.508387.40

Mitochondrial large ribosomal subunit mL63, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_147503 OG7: OG7_0043772 17 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 17 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.506743.30
50S ribosomal protein L17, putative
— Both
TcCLB.503579.110 ⚠
pseudouridylate synthase I, putative
— OG7
TcCLB.511751.180 ⚠
pseudouridine synthase A-like protein, putati
— OG7
TcCLB.503959.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.505807.180 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— OG7
TcCLB.510101.90
hypothetical protein, conserved
— Both
TcCLB.511071.160
hypothetical protein, conserved
— Both
TcCLB.504881.40
Mitochondrial small ribosomal subunit mS53, p
— Both
TcCLB.506625.90
Mitochondrial large ribosomal subunit mL94, p
— Both
TcCLB.511871.40 ⚠
NAD binding domain of 6-phosphogluconate dehy
— Both
TcCLB.508323.94
peptidyl-prolyl cis-trans isomerase, putative
— OG6
TcCLB.507711.280
hypothetical protein, conserved
— Both
TcCLB.506367.140
hypothetical protein, conserved
— Both
TcCLB.511867.100
Mitochondrial large ribosomal subunit mL89, p
— Both
TcCLB.503575.54
Mitochondrial small ribosomal subunit mS59, p
— Both
TcCLB.511739.20
Mitochondrial large ribosomal subunit mL72, p
— Both
TcCLB.510719.74
Mitochondrial large ribosomal subunit mL42, p
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.