TcCLB.511001.240

proteasome activator protein pa26, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_132802 OG7: OG7_0037801 50 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 50 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.504867.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506743.170 ⚠
Met-10+ like-protein, putative
— Both
TcCLB.508307.70 ⚠
hypothetical protein, conserved
— Both
TcCLB.510243.80 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507669.160 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510751.10 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
TcCLB.509537.80 ⚠
TPR repeat, putative
— OG7
TcCLB.509757.30 ⚠
stress-inducible protein STI1-like, putative
— OG7
TcCLB.509381.10 ⚠
mitochondrial import receptor subunit, putati
— OG7
TcCLB.506885.320 ⚠
TPR repeat/Tetratricopeptide repeat, putative
— OG7
TcCLB.509127.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511627.100 ⚠
TPR-repeat protein, putative
— OG7
TcCLB.511737.10 ⚠
small glutamine-rich tetratricopeptide repeat
— OG7
TcCLB.510603.30 ⚠
hypothetical protein, conserved
— Both
TcCLB.510231.20 ⚠
hypothetical protein
— OG7
TcCLB.503893.60 ⚠
UBA/TS-N domain containing protein, putative
— OG7
TcCLB.510761.70 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.506677.10 ⚠
ubiquitin-like protein, putative
— OG7
TcCLB.508277.360 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.506733.140 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511871.40 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
TcCLB.509967.160 ⚠
epsilon tubulin, putative
— OG7
TcCLB.503969.10 ⚠
tubulin delta chain
— OG7
TcCLB.511867.190 ⚠
tubulin gamma chain
— OG7
TcCLB.504867.20 ⚠
ABC transporter, putative
— OG7
TcCLB.504427.200 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
TcCLB.504883.50 ⚠
tRNA synthetases class II (A)/Threonyl and Al
— Both
TcCLB.506563.40 ⚠
beta tubulin, putative
— Both
TcCLB.504153.140 ⚠
metallo-peptidase, Clan MF, Family M17
— Both
TcCLB.511107.41 ⚠
ATP-dependent Clp protease subunit heat shock
— Both
TcCLB.508807.10 ⚠
atp-dependent chaperone, ATP-dependent Clp pr
— Both
TcCLB.509125.20 ⚠
ATP-dependent Clp protease subunit, heat shoc
— Both
TcCLB.503715.10 ⚠
splicing factor TSR1, putative
— Both
TcCLB.508385.60 ⚠
Vta1 like, putative
— Both
TcCLB.510409.10 ⚠
STE/STE11 serine/threonine-protein kinase, pu
— OG6
TcCLB.509167.190 ⚠
STE/STE11 serine/threonine-protein kinase, pu
— OG6
TcCLB.503715.40 ⚠
STE/STE11 serine/threonine-protein kinase, pu
— OG6
TcCLB.505807.180 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— Both
TcCLB.506737.70 ⚠
ubiquitin-like protein, putative
— OG6
TcCLB.507529.50 ⚠
Ankyrin repeats (3 copies), putative
— Both
TcCLB.506251.100 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
TcCLB.504153.290 ⚠
diphthamide biosynthesis enzyme Dph1/Dph2 dom
— Both
TcCLB.506659.30 ⚠
glutathione synthetase, putative
— Both
TcCLB.503639.10 ⚠
inositol-3-phosphate synthase, putative
— Both
TcCLB.510181.9 ⚠
inositol-3-phosphate synthase, putative (frag
— Both
TcCLB.506737.20 ⚠
CMGC/MAPK protein kinase, putative
— Both
TcCLB.510743.10 ⚠
ubiquitin-activating enzyme E1, putative
— Both
TcCLB.504427.250 ⚠
ubiquitin-activating enzyme E1, putative
— Both
TcCLB.504137.80 ⚠
adenylyl cyclase-associated protein, putative
— Both
TcCLB.510741.229 ⚠
ubiquitin-activating enzyme E1, putative
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.