TcCLB.504625.60

hydrogenase, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_101268 OG7: OG7_0005781 75 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 75 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.504203.29 ⚠
tRNA-dihydrouridine synthase 2, putative
— OG7
TcCLB.508169.20 ⚠
elongation factor 2, putative
— OG7
TcCLB.506265.180 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511409.40 ⚠
Zinc finger, C3HC4 type (RING finger), putati
— OG7
TcCLB.509145.10 ⚠
Ankyrin repeats (3 copies)/Zinc finger, C3HC4
— OG7
TcCLB.510053.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.505025.144 ⚠
UEV domain/Zinc finger, C3HC4 type (RING fing
— OG7
TcCLB.506745.4 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcCLB.510105.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504147.190 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508213.9 ⚠
regulator of chromosome condensation, putativ
— OG7
TcCLB.505945.20 ⚠
ribonuclease mar1, putative
— OG7
TcCLB.506941.70
hypothetical protein, conserved
— OG7
TcCLB.509267.50 ⚠
U5 small nuclear ribonucleoprotein component,
— OG7
TcCLB.507625.186 ⚠
Zinc finger, C3HC4 type (RING finger), putati
— OG7
TcCLB.510615.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509097.28 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506885.416 ⚠
regulator of chromosome condensation (RCC1),
— OG7
TcCLB.510719.300 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
TcCLB.506773.180 ⚠
regulator of chromatin condensation, putative
— OG7
TcCLB.511127.350 ⚠
Plus-3 domain/Zinc finger, C3HC4 type (RING f
— OG7
TcCLB.508211.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510593.10 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcCLB.508277.360 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.505945.30 ⚠
ribonuclease mar1, putative
— OG7
TcCLB.510601.30 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
TcCLB.508169.9 ⚠
elongation factor 2, putative (fragment)
— OG7
TcCLB.510377.61 ⚠
UEV domain/Zinc finger, C3HC4 type (RING fing
— OG7
TcCLB.508323.120 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510609.30 ⚠
GTPase, putative
— OG7
TcCLB.508439.30 ⚠
regulator of chromosome condensation 1-like p
— OG7
TcCLB.510761.70 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.504029.60
hypothetical protein, conserved
— OG7
TcCLB.510021.185 ⚠
UEV domain/Zinc finger, C3HC4 type (RING fing
— OG7
TcCLB.510963.90 ⚠
elongation factor 2, putative
— OG7
TcCLB.506967.13 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503489.10 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
TcCLB.506743.220 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503579.100 ⚠
nucleotide-binding protein, putative
— Both
TcCLB.506635.40 ⚠
Regulator of chromosome condensation (RCC1) r
— Both
TcCLB.509125.20 ⚠
ATP-dependent Clp protease subunit, heat shoc
— Both
TcCLB.510743.10 ⚠
ubiquitin-activating enzyme E1, putative
— Both
TcCLB.504077.40 ⚠
translation elongation factor EF-2, putative
— Both
TcCLB.508807.10 ⚠
atp-dependent chaperone, ATP-dependent Clp pr
— Both
TcCLB.511801.20
D123, putative
— Both
TcCLB.508375.30 ⚠
aspartate carbamoyltransferase, putative
— Both
TcCLB.506367.20 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— Both
TcCLB.510533.20 ⚠
Beta-lactamase superfamily domain containing
— Both
TcCLB.509805.80 ⚠
hypothetical protein, conserved
— Both
TcCLB.508583.10
Methyltransferase domain/Methyltransferase in
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.