TcCLB.509967.80

Programmed cell death protein 2, C-terminal putative domain containing protein, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_103161 OG7: OG7_0004545 58 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 58 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.506775.30 ⚠
tubulin-tyrosine ligase-like protein, putativ
— OG7
TcCLB.506107.20 ⚠
dihydrouridine synthase (Dus), putative
— Both
TcCLB.510257.80 ⚠
cytosolic nonspecific dipeptidase, putative
— Both
TcCLB.511747.30 ⚠
C2H2 type zinc-finger (2 copies), putative
— Both
TcCLB.510741.229 ⚠
ubiquitin-activating enzyme E1, putative
— Both
TcCLB.504427.200 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
TcCLB.506251.100 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
TcCLB.509595.50 ⚠
DIS3-like exonuclease, putative
— OG7
TcCLB.509805.220 ⚠
cholinephosphate cytidylyltransferase A, puta
— OG7
TcCLB.505943.20 ⚠
oxidoreductase, putative
— OG7
TcCLB.506735.10 ⚠
metallo-peptidase, Clan ME, Family M16, putat
— OG7
TcCLB.510751.10 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
TcCLB.505945.20 ⚠
ribonuclease mar1, putative
— OG7
TcCLB.509103.20 ⚠
tubulin-tyrosine ligase, putative
— OG7
TcCLB.505945.30 ⚠
ribonuclease mar1, putative
— OG7
TcCLB.504427.250 ⚠
ubiquitin-activating enzyme E1, putative
— Both
TcCLB.506743.210 ⚠
tubulin tyrosine ligase, putative
— OG7
TcCLB.506941.80 ⚠
tubulin-tyrosine ligase-like protein, putativ
— OG7
TcCLB.510141.20 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
TcCLB.506885.270 ⚠
tubulin tyrosine ligase, putative
— OG7
TcCLB.509805.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503557.20 ⚠
ankyrin repeat protein, putative
— OG7
TcCLB.510611.40 ⚠
Ankyrin repeats (3 copies), putative
— OG7
TcCLB.504203.29 ⚠
tRNA-dihydrouridine synthase 2, putative
— OG7
TcCLB.510053.70 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506927.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506265.180 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506773.150 ⚠
hypothetical protein
— OG7
TcCLB.503407.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510101.490 ⚠
anion-transporting ATPase-like, putative
— Both
TcCLB.509803.40 ⚠
5-oxoprolinase, putative
— Both
TcCLB.508241.120 ⚠
rrp44p homologue, putative
— Both
TcCLB.506649.100 ⚠
tRNA nucleotidyltransferase, putative
— Both
TcCLB.511051.59 ⚠
Thiamin pyrophosphokinase, vitamin B1 binding
— Both
TcCLB.508927.10 ⚠
hypothetical protein, conserved
— Both
TcCLB.506207.40 ⚠
WD domain, G-beta repeat, putative
— Both
TcCLB.508469.20 ⚠
hypothetical protein, conserved
— Both
TcCLB.505983.30 ⚠
general transcription factor IIB
— Both
TcCLB.510431.110 ⚠
hypothetical protein
— Both
TcCLB.507669.110 ⚠
hypothetical protein, conserved
— Both
TcCLB.508211.70 ⚠
Protein of unknown function (DUF525), putativ
— Both
TcCLB.510091.100 ⚠
hypothetical protein, conserved
— Both
TcCLB.506775.40 ⚠
hypothetical protein, conserved
— Both
TcCLB.508995.30 ⚠
tubulin-tyrosine ligase, putative
— Both
TcCLB.503881.10 ⚠
kynureninase, putative
— Both
TcCLB.511111.20 ⚠
hypothetical protein
— Both
TcCLB.507547.30 ⚠
Mitochondrial-processing peptidase subunit al
— Both
TcCLB.506691.80 ⚠
Ubiquitin-like domain containing protein, put
— Both
TcCLB.506181.40 ⚠
Uncharacterized ACR, COG1678, putative
— Both
TcCLB.507993.140 ⚠
RNA-binding protein 29, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.