TcCLB.504643.40

U6 snRNA-associated Sm-like protein LSm4, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_102392 OG7: OG7_0003694 39 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:

Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 39 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.510531.54
small nuclear ribonucleoprotein, putative
— OG7
TcCLB.509103.10
pre-mRNA splicing factor 19, putative
— OG7
TcCLB.511583.30
hypothetical protein, conserved
— OG7
TcCLB.503595.19 ⚠
ATP-dependent DEAD/H RNA helicase, putative (
— OG7
TcCLB.510751.10 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
TcCLB.510741.180 ⚠
ATP-dependent RNA helicase, putative
— OG7
TcCLB.506213.120 ⚠
ATP-dependent RNA helicase HEL67
— OG7
TcCLB.511801.60 ⚠
DEAD-box ATP-dependent RNA helicase, mitochon
— OG7
TcCLB.511571.10 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcCLB.507811.30 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcCLB.508837.100
Putative snoRNA binding domain containing pro
— OG7
TcCLB.507611.300
RNA-binding protein 14
— OG7
TcCLB.510091.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510295.40 ⚠
Protein C21orf2 homolog, putative
— OG7
TcCLB.510737.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504077.40 ⚠
translation elongation factor EF-2, putative
— OG7
TcCLB.509267.50 ⚠
U5 small nuclear ribonucleoprotein component,
— OG7
TcCLB.508169.20 ⚠
elongation factor 2, putative
— OG7
TcCLB.510963.90 ⚠
elongation factor 2, putative
— OG7
TcCLB.508169.9 ⚠
elongation factor 2, putative (fragment)
— OG7
TcCLB.511753.50 ⚠
WD domain, G-beta repeat, putative
— OG7
TcCLB.506251.100 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
TcCLB.503479.49 ⚠
U6 snRNA-associated Sm-like protein LSm7p
— +3 more Both
TcCLB.506893.25 ⚠
U6 snRNA-associated Sm-like protein LSm6p
— +2 more OG7
TcCLB.509551.64 ⚠
small nuclear ribonucleoprotein Sm-F, putativ
— +2 more OG7
TcCLB.510091.70 ⚠
U6 snRNA-associated Sm-like protein LSm8, put
— +2 more OG7
TcCLB.509965.30 ⚠
small nuclear ribonucleoprotein Sm-E, putativ
— +2 more OG7
TcCLB.511211.130 ⚠
receptor for activated C kinase 1, putative
— OG7
TcCLB.508831.70
U5 snRNP-specific 40 kDa protein, putative
— OG7
TcCLB.511211.120 ⚠
receptor for activated C kinase 1, putative
— OG7
TcCLB.504427.200 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
TcCLB.511131.50 ⚠
U4/U6 small nuclear ribonuclear protein, puta
— OG7
TcCLB.511189.80
small nuclear ribonucleoprotein SmD2, putativ
— OG7
TcCLB.507041.40
U5 snRNP-associated 102 kDa protein, putative
— OG7
TcCLB.506943.114
U6 snRNA-associated Sm-like protein LSm5p
— OG7
TcCLB.511217.80
U6 snRNA-associated sm-like protein Lsm2
— OG7
TcCLB.466823.10
Checkpoint protein HUS1, putative
— OG7
TcCLB.503829.89
spliceosomal U5 snRNP-specific protein, putat
— OG7
TcCLB.508973.50 ⚠
ATP-dependent RNA helicase DBP2B, putative
— OG7
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.