TcCLB.507529.10

Cell growth-regulating nucleolar protein, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_134529 OG7: OG7_0008529 47 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 47 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.506733.140
hypothetical protein, conserved
— OG7
TcCLB.506659.30
glutathione synthetase, putative
— Both
TcCLB.510531.30
Galactose oxidase, central domain containing
— OG6
TcCLB.511421.210 ⚠
hypothetical protein, conserved
— Both
TcCLB.506795.20
hypothetical protein, conserved
— Both
TcCLB.504625.80
hypothetical protein, conserved
— Both
TcCLB.503821.19
hypothetical protein, conserved
— Both
TcCLB.511707.39 ⚠
Importin subunit beta-4, putative
— OG7
TcCLB.506211.60 ⚠
RNA-binding protein, putative
— OG7
TcCLB.510231.20
hypothetical protein
— OG7
TcCLB.510963.30 ⚠
cap guanine-N7 methyltransferase
— OG7
TcCLB.506739.50 ⚠
ATP-dependent protease ATPase subunit HslU1,
— OG7
TcCLB.511423.104
DNA-directed RNA polymerase 2, RPB12 subunit,
— Both
TcCLB.504057.104 ⚠
phosphatidylinositol phosphate kinase alpha
— OG7
TcCLB.503479.49 ⚠
U6 snRNA-associated Sm-like protein LSm7p
— OG7
TcCLB.510289.30 ⚠
phosphatidylinositol-4-phosphate 5-kinase, pu
— OG7
TcCLB.506893.25 ⚠
U6 snRNA-associated Sm-like protein LSm6p
— OG7
TcCLB.510091.70 ⚠
U6 snRNA-associated Sm-like protein LSm8, put
— OG7
TcCLB.510105.130 ⚠
phosphatidylinositol-4-phosphate 5-kinase typ
— OG7
TcCLB.510309.20 ⚠
MFS transporter, putative
— OG7
TcCLB.508953.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507035.110 ⚠
cAMP response protein 1, putative
— OG7
TcCLB.510879.50 ⚠
regulatory subunit of protein kinase a-like p
— OG7
TcCLB.506227.150 ⚠
protein kinase A regulatory subunit
— OG7
TcCLB.504255.30
hypothetical protein, conserved
— Both
TcCLB.505977.13
serine/threonine-protein kinase, putative (fr
— OG6
TcCLB.508215.10
zinc finger CCCH domain containing protein 17
— Both
TcCLB.506289.50
Nucleolar protein 105, putative
— Both
TcCLB.504019.9 ⚠
Importin-beta N-terminal domain/HEAT-like rep
— Both
TcCLB.511529.9 ⚠
Importin-beta N-terminal domain/HEAT-like rep
— Both
TcCLB.511107.41 ⚠
ATP-dependent Clp protease subunit heat shock
— Both
TcCLB.511127.110 ⚠
ATP-dependent protease ATPase subunit HslU2
— Both
TcCLB.508807.10 ⚠
atp-dependent chaperone, ATP-dependent Clp pr
— Both
TcCLB.509125.20 ⚠
ATP-dependent Clp protease subunit, heat shoc
— Both
TcCLB.508095.20 ⚠
mRNA cap methyltransferase-like protein, puta
— Both
TcCLB.504055.60
hypothetical protein, conserved
— Both
TcCLB.506211.70 ⚠
RNA-binding protein, putative
— Both
TcCLB.506829.10
Dyggve-Melchior-Clausen syndrome protein, put
— Both
TcCLB.506885.430
lipoic acid containing carrier protein, putat
— Both
TcCLB.509551.64 ⚠
small nuclear ribonucleoprotein Sm-F, putativ
— Both
TcCLB.504153.360
succinyl-coA:3-ketoacid-coenzyme A transferas
— Both
TcCLB.509965.30 ⚠
small nuclear ribonucleoprotein Sm-E, putativ
— Both
TcCLB.511001.70 ⚠
phosphatidylinositol-4-phosphate 5-kinase-lik
— Both
TcCLB.504137.10
isoleucyl-tRNA synthetase, putative
— Both
TcCLB.506941.280 ⚠
heat shock 70 kDa protein, mitochondrial prec
— Both
TcCLB.511745.10 ⚠
heat shock 70 kDa protein, mitochondrial prec
— Both
TcCLB.507099.120
hypothetical protein, conserved
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.