TcCLB.508569.70

hypothetical protein, conserved
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_123621 OG7: OG7_0024426 20 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 20 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.510963.30 ⚠
cap guanine-N7 methyltransferase
— OG7
TcCLB.417091.10 ⚠
RNA pseudouridylate synthase, putative
— OG7
TcCLB.511709.19
phosphatidylinositol 3-kinase catalytic subun
— OG7
TcCLB.506135.90 ⚠
RNA pseudouridylate synthase, putative
— OG7
TcCLB.506625.249 ⚠
RNA pseudouridylate synthase protein, putativ
— OG7
TcCLB.503579.110 ⚠
pseudouridylate synthase I, putative
— OG7
TcCLB.506249.20 ⚠
protein transport protein Sec23A, putative
— OG7
TcCLB.503959.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.510609.130
hypothetical protein, conserved
— OG7
TcCLB.506227.230
N-alpha-acetyltransferase 10, NatA catalytic
— OG7
TcCLB.511311.80
N-alpha-acetyltransferase 35, NatC auxiliary
— Both
TcCLB.511585.70
heat shock protein 70 (hsp70), putative
— OG6
TcCLB.506503.10
hypothetical protein, conserved
— Both
TcCLB.511751.180 ⚠
pseudouridine synthase A-like protein, putati
— Both
TcCLB.511427.19
conserved protein, unknown function (fragment
— Both
TcCLB.511429.20
cyclophilin 15, putative
— Both
TcCLB.511575.100 ⚠
protein transport protein SEC23, putative
— Both
TcCLB.507927.40
hypothetical protein, conserved
— Both
TcCLB.464807.20
PA26 p53-induced protein (sestrin), putative
— Both
TcCLB.508095.20 ⚠
mRNA cap methyltransferase-like protein, puta
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.