TcCLB.508389.10

methyltransferase domain containing protein, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_100611 OG7: OG7_0003453 33 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 33 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.506265.30 ⚠
mitochondrial DNA polymerase I protein A, put
— OG7
TcCLB.506893.80 ⚠
monothiol glutaredoxin, putative
— OG7
TcCLB.509073.30 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TcCLB.507603.30 ⚠
PITH domain-containing protein
— OG7
TcCLB.510749.40 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
TcCLB.508647.170 ⚠
DNA polymerase theta
— OG7
TcCLB.506931.10 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
TcCLB.508357.40 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcCLB.511215.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511215.50 ⚠
hypothetical protein, conserved
— Both
TcCLB.506779.170 ⚠
haloacid dehalogenase hydrolase, putative
— OG7
TcCLB.509965.380 ⚠
dTDP-glucose 4,6-dehydratase, putative
— OG7
TcCLB.511751.160 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507509.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507011.30 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
TcCLB.503675.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.511871.40 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
TcCLB.511911.130 ⚠
phosphoglucomutase
— Both
TcCLB.506625.140 ⚠
methyltransferase domain containing protein,
— Both
TcCLB.511179.100 ⚠
monothiol glutaredoxin, putative
— Both
TcCLB.503425.20 ⚠
monothiol glutaredoxin, putative
— Both
TcCLB.506635.60 ⚠
pyroglutamyl-peptidase I, putative
— Both
TcCLB.510293.20 ⚠
cytosolic factor SEC14, putative, phosphatidy
— Both
TcCLB.503803.4 ⚠
serine/threonine protein phosphatase 2A regul
— Both
TcCLB.511425.10 ⚠
serine/threonine protein phosphatase 2A regul
— Both
TcCLB.508347.130 ⚠
deoxyhypusine hydroxylase, putative
— Both
TcCLB.509965.370 ⚠
adenosine kinase, putative
— Both
TcCLB.506165.10 ⚠
hypothetical protein, conserved
— Both
TcCLB.507507.49 ⚠
hypothetical protein, conserved
— Both
TcCLB.508777.100 ⚠
cyclin 1
— Both
TcCLB.505987.50 ⚠
adenosine kinase, putative
— Both
TcCLB.506693.4 ⚠
eukaryotic translation initiation factor 2 su
— Both
TcCLB.505807.180 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.