TcCLB.503855.20

spermidine synthase, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_100634 OG7: OG7_0003460 48 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 48 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.507883.109 ⚠
mitochondrial malate dehydrogenase, putative
— Both
TcCLB.506503.69 ⚠
glycosomal malate dehydrogenase, putative
— OG7
TcCLB.507883.100 ⚠
malate dehydrogenase, putative
— OG7
TcCLB.506239.20 ⚠
Metallopeptidase family M24, putative
— OG7
TcCLB.511691.20 ⚠
cystathionine beta-synthase, cysteine synthas
— Both
TcCLB.447925.10 ⚠
cystathionine beta-synthase, putative (fragme
— OG6
TcCLB.509149.9 ⚠
cystathionine beta-synthase, serine sulfhydry
— Both
TcCLB.508241.149 ⚠
cystathionine beta-synthase, putative (fragme
— Both
TcCLB.508241.140 ⚠
serine sulfhydrylase, cysteine synthase, cyst
— Both
TcCLB.507165.50 ⚠
cysteine synthase, putative
— OG6
TcCLB.510381.10 ⚠
cystathionine beta-synthase, putative
— Both
TcCLB.511691.10 ⚠
cysteine synthase, cystathionine beta-synthas
— Both
TcCLB.509199.24 ⚠
ribose 5-phosphate isomerase type B
— Both
TcCLB.505009.30 ⚠
kinetoplastid-specific phospho-protein phosph
— OG7
TcCLB.504213.80 ⚠
threonine synthase, putative
— Both
TcCLB.511199.9 ⚠
ATP-dependent RNA helicase FAL1, putative (fr
— OG7
TcCLB.503779.30 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506863.80 ⚠
ApaH-like phosphatase ALPH1, putative
— OG7
TcCLB.511585.190 ⚠
Eukaryotic initiation factor 4A-1
— OG7
TcCLB.510143.10 ⚠
FHA domain containing protein, putative
— OG7
TcCLB.508771.20 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
TcCLB.508771.10 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
TcCLB.486465.9 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
TcCLB.504427.10 ⚠
trypanothione synthetase, putative
— OG7
TcCLB.504147.80 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
TcCLB.482471.19 ⚠
ATP-dependent RNA helicase SUB2, putative (fr
— Both
TcCLB.509099.50 ⚠
trypanothione synthetase
— Both
TcCLB.508209.110 ⚠
hypothetical protein, conserved
— Both
TcCLB.507739.40 ⚠
uracil phosphoribosyltransferase, putative
— Both
TcCLB.510315.10 ⚠
inosine-adenosine-guanosine-nucleosidehydrola
— Both
TcCLB.509151.130 ⚠
deoxyuridine triphosphatase, putative, dUTP d
— Both
TcCLB.506937.10 ⚠
cytosolic malate dehydrogenase, putative
— Both
TcCLB.511139.40 ⚠
ATP-dependent RNA helicase SUB2, putative (fr
— Both
TcCLB.507559.80 ⚠
deoxyribose-phosphate aldolase, putative
— Both
TcCLB.504153.180 ⚠
UDP-N-acetylglucosamine pyrophosphorylase, pu
— Both
TcCLB.506857.60 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG6
TcCLB.506211.200 ⚠
metallo-peptidase, Clan MG, Family M24
— Both
TcCLB.507925.40 ⚠
pyridoxal kinase, putative
— Both
TcCLB.511395.30 ⚠
protein phosphatase 2A, regulatory subunit B,
— Both
TcCLB.503899.90 ⚠
asparagine synthetase a, putative
— Both
TcCLB.511555.80 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
TcCLB.506411.10 ⚠
metallo-peptidase, clan MA(E), family M3, put
— Both
TcCLB.511579.9 ⚠
fatty acyl CoA syntetase 1, putative (fragmen
— Both
TcCLB.511581.10 ⚠
fatty acyl CoA synthetase 2, putative
— Both
TcCLB.506829.110 ⚠
fatty acyl CoA synthetase 2, putative
— Both
TcCLB.511581.20 ⚠
fatty acyl CoA syntetase 1 (fragment)
— Both
TcCLB.506829.100 ⚠
fatty acyl CoA syntetase 1, putative
— Both
TcCLB.503575.50 ⚠
fatty acyl CoA synthetase, putative
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.