TcIL3000.11.2040

BRO1-like domain/ALIX V-shaped domain binding to HIV, putative
Trypanosoma congolense IL3000 OG6: OG6_102685 OG7: OG7_0003119 16 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 16 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_0_27070 ⚠
heat shock 70 kDa protein, putative
— Both
TcIL3000_0_53490 ⚠
p22 protein precursor
— Both
TcIL3000_6_1930 ⚠
p22 protein precursor, putative
— Both
TcIL3000_0_31300
co-chaperone GrpE, putative
— Both
TcIL3000_0_08300 ⚠
heat shock 70 kDa protein, putative
— Both
TcIL3000_10_6890 ⚠
prolyl endopeptidase
— Both
TcIL3000_8_2730
5'-3' exoribonuclease C, putative
— Both
TcIL3000_3_2990 ⚠
5-histidylcysteine sulfoxide synthase, putati
— Both
TcIL3000.11.3540 ⚠
metallo-peptidase, Clan MA(E) Family M1, amin
— Both
TcIL3000_0_10480 ⚠
methyltransferase domain containing protein,
— OG7
TcIL3000_7_5760 ⚠
mitochondrial glycoprotein-like protein, puta
— OG7
TcIL3000_0_26670 ⚠
p22 protein precursor, putative
— OG7
TcIL3000_0_42640 ⚠
Aminopeptidase M1, putative
— OG7
TcIL3000_7_4140 ⚠
serine peptidase, clan SC, family S9A-like pr
— OG7
TcIL3000_0_35790 ⚠
oligopeptidase b
— OG7
TcIL3000_5_4750 ⚠
prolyl oligopeptidase, putative
— OG7
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.