TcIL3000_5_4750

prolyl oligopeptidase, putative
Trypanosoma congolense IL3000 OG6: OG6_166284 OG7: OG7_0003174 44 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 44 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_9_2960 ⚠
hypothetical protein, conserved
— OG7
TcIL3000.11.3540 ⚠
metallo-peptidase, Clan MA(E) Family M1, amin
— OG7
TcIL3000_10_8870 ⚠
trypanothione reductase, putative
— OG7
TcIL3000_10_8540 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
TcIL3000_7_10 ⚠
thimet oligopeptidase, putative
— OG7
TcIL3000_10_3350 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_10_3340 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_6_3910 ⚠
valyl-tRNA synthetase, putative
— OG7
TcIL3000_9_60 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_1_360 ⚠
deoxyhypusine synthase, putative
— OG7
TcIL3000.11.13360 ⚠
Uncharacterised protein family (UPF0160), put
— OG7
TcIL3000_0_42640 ⚠
Aminopeptidase M1, putative
— OG7
TcIL3000_0_01930 ⚠
Uncharacterised protein family (UPF0160), put
— OG7
TcIL3000_0_58210 ⚠
hypothetical protein (fragment)
— OG7
TcIL3000_10_11740 ⚠
tubulin-specific chaperone, putative
— OG7
TcIL3000.11.10140 ⚠
glycyl-tRNA synthetase, putative
— OG7
TcIL3000_5_2370 ⚠
sodium/hydrogen exchanger, putative
— OG7
TcIL3000.11.11710 ⚠
translation initiation factor 2 subunit, puta
— OG7
TcIL3000.11.2040 ⚠
BRO1-like domain/ALIX V-shaped domain binding
— OG7
TcIL3000_1_1430 ⚠
amidohydrolase, putative
— OG7
TcIL3000_0_07180 ⚠
sodium/hydrogen exchanger, putative
— OG7
TcIL3000.11.3680 ⚠
leucyl-tRNA synthetase, putative
— OG7
TcIL3000_0_10480 ⚠
methyltransferase domain containing protein,
— OG7
TcIL3000_8_7090 ⚠
peptidase, putative
— OG7
TcIL3000_8_7000 ⚠
metallo-peptidase, Clan ME, Family M16, putat
— OG7
TcIL3000_10_2660 ⚠
delta-1-pyrroline-5-carboxylate dehydrogenase
— OG7
TcIL3000_4_770 ⚠
ruvB-like DNA helicase, putative
— OG7
TcIL3000_4_1750 ⚠
ruvB-like DNA helicase, putative
— OG7
TcIL3000_2_770 ⚠
trypanothione synthetase
— OG7
TcIL3000_0_44670 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
TcIL3000_0_26910 ⚠
trypanothione synthetase, putative (fragment)
— OG7
TcIL3000_0_44680 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
TcIL3000.11.9130 ⚠
glutathionylspermidine synthetase, putative
— OG7
TcIL3000_7_1870 ⚠
Uncharacterised protein family UPF0066, putat
— OG7
TcIL3000_3_2990 ⚠
5-histidylcysteine sulfoxide synthase, putati
— OG7
TcIL3000_10_2180 ⚠
malate dehydrogenase-related
— OG7
TcIL3000_10_13190 ⚠
glycosomal malate dehydrogenase, putative
— OG7
TcIL3000_10_2190 ⚠
mitochondrial malate dehydrogenase
— OG7
TcIL3000_6_4220 ⚠
T-complex protein 11, putative
— OG7
TcIL3000_9_5070 ⚠
Peroxin 19
— OG7
TcIL3000_0_33380 ⚠
Present in the outer mitochondrial membrane p
— OG7
TcIL3000_0_11290 ⚠
conserved hypothetical protein, putative (fra
— OG7
TcIL3000_6_1890 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_00410 ⚠
Present in the outer mitochondrial membrane p
— OG7
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.