TcIL3000.11.3680

leucyl-tRNA synthetase, putative
Trypanosoma congolense IL3000 OG6: OG6_101014 OG7: OG7_0005523 118 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 118 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_10_7960
isoleucyl-tRNA synthetase, putative (fragment
— Both
TcIL3000_10_1300
methionyl-tRNA synthetase, putative
— Both
TcIL3000.11.10140
glycyl-tRNA synthetase, putative
— Both
TcIL3000_3_3520 ⚠
tryptophanyl-tRNA synthetase, putative
— Both
TcIL3000_0_30560 ⚠
tryptophanyl-tRNA synthetase
— Both
TcIL3000_6_3910
valyl-tRNA synthetase, putative
— Both
TcIL3000_8_2240 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
TcIL3000_8_5170
tyrosyl/methionyl-tRNA synthetase, putative
— OG7
TcIL3000_8_6790 ⚠
translation initiation factor IF-2, putative
— OG7
TcIL3000_8_5630
SMP-30/Gluconolaconase/LRE-like region, putat
— Both
TcIL3000_7_580
protein kinase C substrate protein, heavy cha
— Both
TcIL3000_10_10990
bifunctional aminoacyl-tRNA synthetase, putat
— Both
TcIL3000.11.7230
hypothetical protein, conserved
— Both
TcIL3000_7_4570
glucosamine-fructose-6-phosphate aminotransfe
— Both
TcIL3000_4_4260 ⚠
calreticulin, putative
— Both
TcIL3000_8_7620 ⚠
calreticulin, putative
— Both
TcIL3000_0_16790 ⚠
calreticulin, putative
— Both
TcIL3000_7_1550
hypothetical protein, conserved
— Both
TcIL3000_2_400 ⚠
kinetoplast polyadenylation/uridylation facto
— Both
TcIL3000_7_2430 ⚠
translation initiation factor IF-2, putative
— Both
TcIL3000_7_1870
Uncharacterised protein family UPF0066, putat
— Both
TcIL3000_6_250
alanyl-tRNA synthetase, putative
— Both
TcIL3000_0_33410 ⚠
hypothetical protein (fragment)
— OG6
TcIL3000_7_5720 ⚠
hypothetical protein, conserved
— Both
TcIL3000.11.8840 ⚠
DIS3-like exonuclease, putative
— Both
TcIL3000_2_390
Gar1/Naf1 RNA binding region, putative
— Both
TcIL3000_3_1740 ⚠
inorganic pyrophosphatase, putative
— Both
TcIL3000_0_38820 ⚠
acidocalcisomal pyrophosphatase
— Both
TcIL3000.11.7660 ⚠
acidocalcisomal pyrophosphatase
— Both
TcIL3000_9_2450 ⚠
exoribonuclease DSS-1 (EMBL:AY233297), putati
— OG7
TcIL3000.11.8070 ⚠
exosome complex exonuclease RRP44p homologue
— OG7
TcIL3000_0_33680 ⚠
hypothetical protein (fragment)
— OG7
TcIL3000_0_10490 ⚠
serine/threonine protein kinase, putative
— OG7
TcIL3000_4_2920 ⚠
tRNA-dihydrouridine synthase 4, putative
— OG7
TcIL3000_10_6890 ⚠
prolyl endopeptidase
— OG7
TcIL3000_7_5060 ⚠
protein kinase, putative
— OG7
TcIL3000_10_2630 ⚠
ABC transporter, putative
— OG7
TcIL3000_0_32980 ⚠
protein kinase, putative
— OG7
TcIL3000_8_7960 ⚠
tRNA-dihydrouridine synthase 1, putative
— OG7
TcIL3000_10_1050 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
TcIL3000_5_4750 ⚠
prolyl oligopeptidase, putative
— OG7
TcIL3000_5_2300 ⚠
NOL1/NOP2/sun family, putative
— OG7
TcIL3000_10_7530 ⚠
GTPase activating protein, putative
— OG7
TcIL3000_3_2180 ⚠
cytochrome b5, putative
— OG7
TcIL3000_0_57140 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcIL3000_6_1770 ⚠
NUDC-like protein, putative, nuclear movement
— OG7
TcIL3000_7_210 ⚠
cytochrome b5-like Heme/Steroid binding domai
— OG7
TcIL3000_2_1340 ⚠
protein kinase, putative
— OG7
TcIL3000_0_14160 ⚠
dihydrouridine synthase (Dus), putative (frag
— OG7
TcIL3000_0_23020 ⚠
tRNA-dihydrouridine synthase 1, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.