TcIL3000_10_1300

methionyl-tRNA synthetase, putative
Trypanosoma congolense IL3000 OG6: OG6_101119 OG7: OG7_0003306 141 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 141 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_0_25100 ⚠
histidyl-tRNA synthetase
— Both
TcIL3000_6_1720 ⚠
histidyl-tRNA synthetase
— Both
TcIL3000_8_5170
tyrosyl/methionyl-tRNA synthetase, putative
— +2 more Both
TcIL3000_6_3910
valyl-tRNA synthetase, putative
— Both
TcIL3000.11.3680
leucyl-tRNA synthetase, putative
— Both
TcIL3000_3_2180 ⚠
cytochrome b5, putative
— OG7
TcIL3000_2_400 ⚠
kinetoplast polyadenylation/uridylation facto
— Both
TcIL3000_10_9950
hypothetical protein, conserved
— Both
TcIL3000_0_24310 ⚠
hypothetical protein (fragment)
— Both
TcIL3000.11.2280 ⚠
metallo-peptidase, Clan MF, Family M17 (fragm
— Both
TcIL3000_7_2430 ⚠
translation initiation factor IF-2, putative
— Both
TcIL3000_9_410
WD domain, G-beta repeat, putative
— Both
TcIL3000_3_1340
eukaryotic translation initiation factor 3 su
— Both
TcIL3000_10_13840
glucosidase, putative
— Both
TcIL3000_10_5740 ⚠
hypothetical protein, conserved, member of th
— Both
TcIL3000_3_2120 ⚠
NOL1/NOP2/sun family, putative
— Both
TcIL3000_10_3270
hypothetical protein, conserved
— Both
TcIL3000_3_2810 ⚠
Glycosyl transferase family 8, putative
— Both
TcIL3000_3_2820 ⚠
UDP-glucose:glycoprotein glucosyltransferase,
— Both
TcIL3000_0_43380 ⚠
UDP-glucose:glycoprotein glucosyltransferase,
— Both
TcIL3000_2_1260 ⚠
TPR-repeat protein, putative
— OG6
TcIL3000_10_3650 ⚠
stress-inducible protein STI1-like, putative
— OG6
TcIL3000.11.120 ⚠
cleavage and polyadenylation specificity fact
— Both
TcIL3000.11.110 ⚠
cleavage and polyadenylation specificity fact
— Both
TcIL3000_6_250
alanyl-tRNA synthetase, putative
— Both
TcIL3000_0_33410 ⚠
hypothetical protein (fragment)
— OG6
TcIL3000_7_5720 ⚠
hypothetical protein, conserved
— Both
TcIL3000_10_7960
isoleucyl-tRNA synthetase, putative (fragment
— Both
TcIL3000.11.8840 ⚠
DIS3-like exonuclease, putative
— Both
TcIL3000_6_1480 ⚠
aspartyl-tRNA synthetase, putative
— Both
TcIL3000_10_1050 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— Both
TcIL3000_0_31300
co-chaperone GrpE, putative
— Both
TcIL3000_2_390
Gar1/Naf1 RNA binding region, putative
— Both
TcIL3000_3_1740 ⚠
inorganic pyrophosphatase, putative
— Both
TcIL3000_0_38820 ⚠
acidocalcisomal pyrophosphatase
— Both
TcIL3000.11.7660 ⚠
acidocalcisomal pyrophosphatase
— Both
TcIL3000_9_2450 ⚠
exoribonuclease DSS-1 (EMBL:AY233297), putati
— OG7
TcIL3000.11.8070 ⚠
exosome complex exonuclease RRP44p homologue
— OG7
TcIL3000_0_35010 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
TcIL3000_0_14160 ⚠
dihydrouridine synthase (Dus), putative (frag
— OG7
TcIL3000_0_57140 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcIL3000_5_2300 ⚠
NOL1/NOP2/sun family, putative
— OG7
TcIL3000_0_48690 ⚠
heat shock protein 90, putative
— OG7
TcIL3000_3_2270 ⚠
heat shock protein 90, putative
— OG7
TcIL3000_0_26120 ⚠
Hsp90 protein, putative (fragment)
— OG7
TcIL3000_0_26140 ⚠
Heat shock protein 83, putative
— OG7
TcIL3000_0_26130 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
TcIL3000_0_23020 ⚠
tRNA-dihydrouridine synthase 1, putative
— OG7
TcIL3000_4_2920 ⚠
tRNA-dihydrouridine synthase 4, putative
— OG7
TcIL3000_8_7960 ⚠
tRNA-dihydrouridine synthase 1, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.