TcIL3000_6_1720

histidyl-tRNA synthetase
Trypanosoma congolense IL3000 OG6: OG6_100351 OG7: OG7_0003181 108 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 108 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_6_3910 ⚠
valyl-tRNA synthetase, putative
— Both
TcIL3000_10_1300 ⚠
methionyl-tRNA synthetase, putative
— Both
TcIL3000_0_23020 ⚠
tRNA-dihydrouridine synthase 1, putative
— OG7
TcIL3000_8_5630 ⚠
SMP-30/Gluconolaconase/LRE-like region, putat
— Both
TcIL3000_7_580 ⚠
protein kinase C substrate protein, heavy cha
— Both
TcIL3000.11.7230 ⚠
hypothetical protein, conserved
— Both
TcIL3000_7_4570 ⚠
glucosamine-fructose-6-phosphate aminotransfe
— Both
TcIL3000_4_4260 ⚠
calreticulin, putative
— Both
TcIL3000_8_7620 ⚠
calreticulin, putative
— Both
TcIL3000_0_16790 ⚠
calreticulin, putative
— Both
TcIL3000_7_1550 ⚠
hypothetical protein, conserved
— Both
TcIL3000_2_400 ⚠
kinetoplast polyadenylation/uridylation facto
— Both
TcIL3000_7_2430 ⚠
translation initiation factor IF-2, putative
— Both
TcIL3000.11.16070 ⚠
nucleoside diphosphate kinase
— Both
TcIL3000_6_250 ⚠
alanyl-tRNA synthetase, putative
— Both
TcIL3000_0_33410 ⚠
hypothetical protein (fragment)
— OG6
TcIL3000_7_5720 ⚠
hypothetical protein, conserved
— Both
TcIL3000.11.8840 ⚠
DIS3-like exonuclease, putative
— Both
TcIL3000_2_390 ⚠
Gar1/Naf1 RNA binding region, putative
— Both
TcIL3000_3_1740 ⚠
inorganic pyrophosphatase, putative
— Both
TcIL3000_0_38820 ⚠
acidocalcisomal pyrophosphatase
— Both
TcIL3000.11.7660 ⚠
acidocalcisomal pyrophosphatase
— Both
TcIL3000_9_2450 ⚠
exoribonuclease DSS-1 (EMBL:AY233297), putati
— OG7
TcIL3000.11.8070 ⚠
exosome complex exonuclease RRP44p homologue
— OG7
TcIL3000_7_210 ⚠
cytochrome b5-like Heme/Steroid binding domai
— OG7
TcIL3000_3_2180 ⚠
cytochrome b5, putative
— OG7
TcIL3000_6_1480 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcIL3000_10_9180 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
TcIL3000_0_57140 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcIL3000_8_6790 ⚠
translation initiation factor IF-2, putative
— OG7
TcIL3000_9_5280 ⚠
pentatricopeptide repeat domain containing pr
— OG7
TcIL3000_0_33680 ⚠
hypothetical protein (fragment)
— OG7
TcIL3000_4_2920 ⚠
tRNA-dihydrouridine synthase 4, putative
— OG7
TcIL3000_7_5060 ⚠
protein kinase, putative
— OG7
TcIL3000_10_2630 ⚠
ABC transporter, putative
— OG7
TcIL3000_0_32980 ⚠
protein kinase, putative
— OG7
TcIL3000_8_7960 ⚠
tRNA-dihydrouridine synthase 1, putative
— OG7
TcIL3000_8_5170 ⚠
tyrosyl/methionyl-tRNA synthetase, putative
— OG7
TcIL3000_10_1050 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
TcIL3000_5_2300 ⚠
NOL1/NOP2/sun family, putative
— OG7
TcIL3000_10_7530 ⚠
GTPase activating protein, putative
— OG7
TcIL3000_8_2240 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
TcIL3000_8_7820 ⚠
dihydrouridine synthase (Dus), putative
— OG7
TcIL3000_0_14160 ⚠
dihydrouridine synthase (Dus), putative (frag
— OG7
TcIL3000_2_1340 ⚠
protein kinase, putative
— OG7
TcIL3000_4_840 ⚠
cleavage and polyadenylation specificity fact
— OG7
TcIL3000_10_11080 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
TcIL3000_0_56880 ⚠
protein kinase, putative
— OG7
TcIL3000_0_29040 ⚠
protein kinase, putative (fragment)
— OG7
TcIL3000_10_4060 ⚠
tRNA-dihydrouridine synthase 2, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.