TcIL3000_10_11080

Multisite-specific tRNA:(cytosine-C(5))-methyltransferase, putative
Trypanosoma congolense IL3000 OG6: OG6_139680 OG7: OG7_0004943 144 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 144 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_1_1470 ⚠
tRNA (Uracil-5-)-methyltransferase, putative
— OG7
TcIL3000_10_1300 ⚠
methionyl-tRNA synthetase, putative
— OG7
TcIL3000_7_3480 ⚠
N-terminal conserved domain of Nudc./CS domai
— OG7
TcIL3000.11.8380 ⚠
ribonucleoside-diphosphate reductase large ch
— OG7
TcIL3000_0_23020 ⚠
tRNA-dihydrouridine synthase 1, putative
— OG7
TcIL3000_0_14160 ⚠
dihydrouridine synthase (Dus), putative (frag
— OG7
TcIL3000_2_1340 ⚠
protein kinase, putative
— OG7
TcIL3000_4_840 ⚠
cleavage and polyadenylation specificity fact
— OG7
TcIL3000_0_56880 ⚠
protein kinase, putative
— OG7
TcIL3000_0_29040 ⚠
protein kinase, putative (fragment)
— OG7
TcIL3000_0_48690 ⚠
heat shock protein 90, putative
— OG7
TcIL3000_10_13840 ⚠
glucosidase, putative
— OG7
TcIL3000_8_7820 ⚠
dihydrouridine synthase (Dus), putative
— OG7
TcIL3000_10_13100 ⚠
hypothetical protein
— OG7
TcIL3000_10_13090 ⚠
protein kinase, putative
— OG7
TcIL3000_10_3270 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_9_410 ⚠
WD domain, G-beta repeat, putative
— OG7
TcIL3000_10_4060 ⚠
tRNA-dihydrouridine synthase 2, putative
— OG7
TcIL3000_1_1150 ⚠
Pre-mRNA-splicing factor 38, putative
— OG7
TcIL3000_0_10490 ⚠
serine/threonine protein kinase, putative
— OG7
TcIL3000_3_2270 ⚠
heat shock protein 90, putative
— OG7
TcIL3000_7_5350 ⚠
tRNA-dihydrouridine synthase 3, putative
— OG7
TcIL3000_10_3710 ⚠
PUB domain containing protein, putative
— OG7
TcIL3000_3_1340 ⚠
eukaryotic translation initiation factor 3 su
— OG7
TcIL3000_6_1770 ⚠
NUDC-like protein, putative, nuclear movement
— OG7
TcIL3000_10_3350 ⚠
hypothetical protein, conserved
— OG7
TcIL3000.11.7170 ⚠
hypothetical protein (fragment)
— OG7
TcIL3000_9_3760 ⚠
hypothetical protein
— OG7
TcIL3000.11.890 ⚠
Nuclear pore complex protein 158 (fragment),
— OG7
TcIL3000.11.110 ⚠
cleavage and polyadenylation specificity fact
— OG7
TcIL3000_8_2240 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
TcIL3000_10_6100 ⚠
myo-inositol-1-phosphate synthase, putative
— OG7
TcIL3000_10_3290 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_26140 ⚠
Heat shock protein 83, putative
— OG7
TcIL3000_0_26130 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
TcIL3000_5_910 ⚠
peroxisome targeting signal 1 receptor
— OG7
TcIL3000.11.11440 ⚠
VHS domain containing protein, putative
— OG7
TcIL3000_6_3910 ⚠
valyl-tRNA synthetase, putative
— OG7
TcIL3000.11.10810 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_11560 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_10_13410 ⚠
tRNA pseudouridine synthase A-like protein, p
— OG7
TcIL3000_7_1020 ⚠
pseudouridylate synthase I, putative
— OG7
TcIL3000_6_2460 ⚠
pseudouridine synthase A-like protein, putati
— OG7
TcIL3000_10_2340 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_7_5720 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_7_4570 ⚠
glucosamine-fructose-6-phosphate aminotransfe
— OG7
TcIL3000.11.3680 ⚠
leucyl-tRNA synthetase, putative
— OG7
TcIL3000_7_2430 ⚠
translation initiation factor IF-2, putative
— OG7
TcIL3000_8_6790 ⚠
translation initiation factor IF-2, putative
— OG7
TcIL3000_0_51320 ⚠
Possible lysine decarboxylase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.