TcIL3000.11.8380

ribonucleoside-diphosphate reductase large chain
Trypanosoma congolense IL3000 OG6: OG6_100448 OG7: OG7_0004229 105 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 105 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_10_6920 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_6_1530 ⚠
N-acetyltransferase B complex (NatB) non cata
— Both
TcIL3000_0_48970 ⚠
N-acetyltransferase B complex (NatB) non cata
— Both
TcIL3000_0_43620 ⚠
isocitrate dehydrogenase, putative
— Both
TcIL3000_0_02490 ⚠
hypothetical protein, conserved
— Both
TcIL3000_7_5710 ⚠
methylthioadenosine phosphorylase, putative
— Both
TcIL3000.11.2680 ⚠
Domain of unknown function (DUF383), putative
— Both
TcIL3000_0_17960 ⚠
hypothetical protein, conserved
— Both
TcIL3000_0_42660 ⚠
leucine-rich repeat-containing protein
— Both
TcIL3000.11.11710 ⚠
translation initiation factor 2 subunit, puta
— Both
TcIL3000_10_8270 ⚠
paraflagellar rod component, putative
— Both
TcIL3000_8_2420 ⚠
5-methyltetrahydropteroyltriglutamate-homocys
— Both
TcIL3000_6_4120 ⚠
hypothetical protein, conserved
— Both
TcIL3000_0_33390 ⚠
Sperm-tail PG-rich repeat, putative
— Both
TcIL3000_8_6320 ⚠
protein kinase, putative
— Both
TcIL3000_0_38090 ⚠
hypothetical protein
— Both
TcIL3000_8_3980 ⚠
hypothetical protein, conserved
— Both
TcIL3000.11.8840 ⚠
DIS3-like exonuclease, putative
— Both
TcIL3000_0_37750 ⚠
conserved protein, unknown function
— Both
TcIL3000_0_53370 ⚠
conserved protein, unknown function
— Both
TcIL3000_9_2450 ⚠
exoribonuclease DSS-1 (EMBL:AY233297), putati
— OG7
TcIL3000.11.8070 ⚠
exosome complex exonuclease RRP44p homologue
— OG7
TcIL3000_6_3320 ⚠
leucyl/phenylalanyl-tRNA protein transferase,
— OG7
TcIL3000_0_42490 ⚠
TFIIF-stimulated CTD phosphatase, putative
— OG7
TcIL3000_3_1220 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_10_9680 ⚠
TFIIF-stimulated CTD phosphatase, putative
— OG7
TcIL3000_9_5560 ⚠
TFIIF-stimulated CTD phosphatase, putative
— OG7
TcIL3000.11.9540 ⚠
ADP-ribosylation factor GTPase activating pro
— OG7
TcIL3000_8_1750 ⚠
nonspecific lipid-transfer protein, putative,
— OG7
TcIL3000_0_31970 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcIL3000_0_35010 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
TcIL3000_0_26120 ⚠
Hsp90 protein, putative (fragment)
— OG7
TcIL3000_0_26130 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
TcIL3000_0_26140 ⚠
Heat shock protein 83, putative
— OG7
TcIL3000_5_2300 ⚠
NOL1/NOP2/sun family, putative
— OG7
TcIL3000_0_04870 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcIL3000.11.7170 ⚠
hypothetical protein (fragment)
— OG7
TcIL3000_0_57140 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcIL3000_6_1770 ⚠
NUDC-like protein, putative, nuclear movement
— OG7
TcIL3000_4_2130 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
TcIL3000_0_26010 ⚠
ADP-ribosylation factor GTPase activating pro
— OG7
TcIL3000_10_3480 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_10200 ⚠
TFIIF-stimulated CTD phosphatase, putative
— OG7
TcIL3000.11.7610 ⚠
serine/threonine protein kinase, putative
— OG7
TcIL3000.11.7630 ⚠
protein kinase, putative
— OG7
TcIL3000_6_4400 ⚠
serine/arginine-rich protein specific kinase
— OG7
TcIL3000_3_3280 ⚠
centaurin beta 5, ADP-ribosylation factor GTP
— OG7
TcIL3000_9_6580 ⚠
ADP-ribosylation factor GTPase activating pro
— OG7
TcIL3000_3_2270 ⚠
heat shock protein 90, putative
— OG7
TcIL3000_0_06580 ⚠
ADP-ribosylation factor GTPase activating pro
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.