TcIL3000_0_26120

Hsp90 protein, putative (fragment)

Trypanosoma congolense IL3000 OG6: OG6_100204 OG7: OG7_0001978 158 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 158 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TcIL3000_10_11660 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_006181 ↔ TCSYLVIO_010666 OG7 Tb927.10.14030 ↔ Tb927.3.3580	OG7
TcIL3000_9_1990 ⚠ glutamate dehydrogenase	—	OG6 LdBPK_151070.1 ↔ LdBPK_330360.1 OG6 TCSYLVIO_002205 ↔ TCSYLVIO_007064 OG6 TCSYLVIO_007064 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_007064 ↔ TCSYLVIO_009400 +6 more	Both
TcIL3000_8_3100 ⚠ coronin, putative (fragment)	—	OG6 TCSYLVIO_000174 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_000174 ↔ TCSYLVIO_009400 OG6 TCSYLVIO_000174 ↔ TCSYLVIO_009151 OG6 Tb927.10.10960 ↔ Tb927.8.3100 +4 more	Both
TcIL3000_0_48690 ⚠ heat shock protein 90, putative	—	OG7 LdBPK_290790.1 ↔ LdBPK_330360.1 OG7 TCSYLVIO_002205 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_008593 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_009151 ↔ TCSYLVIO_009400 +4 more	OG7
TcIL3000_8_5170 ⚠ tyrosyl/methionyl-tRNA synthetase, putative	—	OG6 LdBPK_161170.1 ↔ LdBPK_330360.1 OG7 TCSYLVIO_001244 ↔ TCSYLVIO_005578 OG7 LdBPK_161170.1 ↔ LdBPK_330360.1	Both
TcIL3000_3_2270 ⚠ heat shock protein 90, putative	—	OG7 LdBPK_290790.1 ↔ LdBPK_330360.1 OG7 TCSYLVIO_002205 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_008593 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_009151 ↔ TCSYLVIO_009400 +4 more	OG7
TcIL3000.11.2400 ⚠ heat shock protein, mitochondrial precursor,	—	OG7 LdBPK_290790.1 ↔ LdBPK_330360.1 OG7 TCSYLVIO_002205 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_008593 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_009151 ↔ TCSYLVIO_009400 +4 more	OG7
TcIL3000_0_13010 ⚠ WD domain, G-beta repeat, putative	—	OG6 TCSYLVIO_009151 ↔ TCSYLVIO_010560 OG6 TCSYLVIO_009400 ↔ TCSYLVIO_010560 OG6 TCSYLVIO_008621 ↔ TCSYLVIO_010560 OG7 Tb927.3.3580 ↔ Tb927.5.3260 +3 more	Both
TcIL3000_0_21000 ⚠ hypothetical protein, conserved (fragment)	—	OG6 TCSYLVIO_009151 ↔ TCSYLVIO_010560 OG6 TCSYLVIO_009400 ↔ TCSYLVIO_010560 OG6 TCSYLVIO_008621 ↔ TCSYLVIO_010560 OG7 Tb927.3.3580 ↔ Tb927.5.3260 +3 more	Both
TcIL3000_0_30110 ⚠ WD domain, G-beta repeat, putative	—	OG6 TCSYLVIO_009151 ↔ TCSYLVIO_010560 OG6 TCSYLVIO_009400 ↔ TCSYLVIO_010560 OG6 TCSYLVIO_008621 ↔ TCSYLVIO_010560 OG7 Tb927.3.3580 ↔ Tb927.5.3260 +3 more	Both
TcIL3000_0_26140 ⚠ Heat shock protein 83, putative	—	OG6 LdBPK_290790.1 ↔ LdBPK_330360.1 OG6 TCSYLVIO_002205 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_008593 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_009151 ↔ TCSYLVIO_009400 +12 more	Both
TcIL3000_0_26130 ⚠ Histidine kinase-, DNA gyrase B-, and HSP90-l	—	OG6 LdBPK_290790.1 ↔ LdBPK_330360.1 OG6 TCSYLVIO_002205 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_008593 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_009151 ↔ TCSYLVIO_009400 +12 more	Both
TcIL3000_9_1300 ⚠ Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1	—	OG7 TCSYLVIO_003436 ↔ TCSYLVIO_010666	OG7
TcIL3000_10_5680 ⚠ chaperone protein DnaJ, putative	—	OG7 TCSYLVIO_003497 ↔ TCSYLVIO_005578	OG7
TcIL3000_9_5260 ⚠ chaperone protein DNAj, putative (fragment)	—	OG7 TCSYLVIO_003497 ↔ TCSYLVIO_005578	OG7
TcIL3000_9_2840 ⚠ chaperone protein DnaJ, putative	—	OG7 TCSYLVIO_003497 ↔ TCSYLVIO_005578	OG7
TcIL3000_2_1270 ⚠ chaperone protein DnaJ, putative	—	OG7 TCSYLVIO_003497 ↔ TCSYLVIO_005578	OG7
TcIL3000_10_1900 ⚠ chaperone protein DNAj, putative (fragment)	—	OG7 TCSYLVIO_003497 ↔ TCSYLVIO_005578	OG7
TcIL3000_0_15550 ⚠ chaperone protein DnaJ, putative	—	OG7 TCSYLVIO_003497 ↔ TCSYLVIO_005578	OG7
TcIL3000_10_2740 ⚠ DnaJ domain/Transmembrane Fragile-X-F protein	—	OG7 TCSYLVIO_003497 ↔ TCSYLVIO_005578	OG7
TcIL3000_8_600 ⚠ 6-phosphofructo-2-kinase/fructose-2,6-biphosp	—	OG7 TCSYLVIO_002376 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_002376 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_002376 ↔ TCSYLVIO_009151	OG7
TcIL3000_3_1660 ⚠ 6-phosphofructo-2-kinase 1	—	OG7 TCSYLVIO_002376 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_002376 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_002376 ↔ TCSYLVIO_009151	OG7
TcIL3000_10_3720 ⚠ 6-phosphofructo-2-kinase/fructose-2,6-bisphos	—	OG7 TCSYLVIO_002376 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_002376 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_002376 ↔ TCSYLVIO_009151	OG7
TcIL3000.11.7720 ⚠ NGG1 interacting factor 3-like	—	OG7 TCSYLVIO_001715 ↔ TCSYLVIO_005578	OG7
TcIL3000_0_40080 ⚠ NGG1 interacting factor 3-like	—	OG7 TCSYLVIO_001715 ↔ TCSYLVIO_005578	OG7
TcIL3000_10_710 ⚠ hook complex protein, conserved (fragment)	—	OG7 TCSYLVIO_005619 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_005619 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_005619 ↔ TCSYLVIO_009151	OG7
TcIL3000_10_9950 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_004910 ↔ TCSYLVIO_005578	OG7
TcIL3000.11.5770 ⚠ synaptojanin (N-terminal domain), putative	—	OG7 TCSYLVIO_007569 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_007569 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_007569 ↔ TCSYLVIO_009151	OG7
TcIL3000_9_4170 ⚠ synaptojanin (N-terminal domain), putative	—	OG7 TCSYLVIO_007569 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_007569 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_007569 ↔ TCSYLVIO_009151	OG7
TcIL3000_9_1900 ⚠ inositol/phosphatidylinositol phosphatase, pu	—	OG7 TCSYLVIO_007569 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_007569 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_007569 ↔ TCSYLVIO_009151	OG7
TcIL3000_10_4640 ⚠ endonuclease/exonuclease/phosphatase, putativ	—	OG7 TCSYLVIO_007569 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_007569 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_007569 ↔ TCSYLVIO_009151	OG7
TcIL3000_9_5730 ⚠ ribonuclease, putative	—	OG7 TCSYLVIO_000055 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_009151	OG7
TcIL3000_9_6340 ⚠ 60S ribosomal protein L5, putative	—	OG7 TCSYLVIO_001078 ↔ TCSYLVIO_010666	OG7
TcIL3000_9_410 ⚠ WD domain, G-beta repeat, putative	—	OG7 TCSYLVIO_005180 ↔ TCSYLVIO_005578	OG7
TcIL3000_10_10010 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_330360.1 ↔ LdBPK_331280.1	OG7
TcIL3000_4_1930 ⚠ GTP-binding protein, putative	—	OG7 LdBPK_330360.1 ↔ LdBPK_332930.1	OG7
TcIL3000.11.14500 ⚠ Staphylococcal nuclease homologue/Tudor domai	—	OG7 Tb927.11.14190 ↔ Tb927.11.2650	OG7
TcIL3000_0_47810 ⚠ ubiquitin carboxyl-terminal hydrolase, putati	—	OG7 TCSYLVIO_005374 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_005374 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_005374 ↔ TCSYLVIO_009151	OG7
TcIL3000_6_1480 ⚠ aspartyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_005578	OG7
TcIL3000_10_1050 ⚠ OB-fold nucleic acid binding domain/tRNA synt	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_005578	OG7
TcIL3000_5_910 ⚠ peroxisome targeting signal 1 receptor	—	OG7 TCSYLVIO_005361 ↔ TCSYLVIO_005578	OG7
TcIL3000.11.9810 ⚠ hypothetical protein	—	OG7 TCSYLVIO_009198 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_009151 ↔ TCSYLVIO_009198 OG7 TCSYLVIO_008621 ↔ TCSYLVIO_009198	OG7
TcIL3000_10_7960 ⚠ isoleucyl-tRNA synthetase, putative (fragment	—	OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005578	OG7
TcIL3000_0_36870 ⚠ Paraflagellar Rod Proteome Component 9, putat	—	OG7 TCSYLVIO_004135 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_004135 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_004135 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_002205 ↔ TCSYLVIO_004135	OG7
TcIL3000_3_1340 ⚠ eukaryotic translation initiation factor 3 su	—	OG7 TCSYLVIO_005578 ↔ TCSYLVIO_006404	OG7
TcIL3000_1_1430 ⚠ amidohydrolase, putative	—	OG7 TCSYLVIO_005578 ↔ TCSYLVIO_008414	OG7
TcIL3000_10_1300 ⚠ methionyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_005578 ↔ TCSYLVIO_007991	OG7
TcIL3000.11.11440 ⚠ VHS domain containing protein, putative	—	OG7 TCSYLVIO_005578 ↔ TCSYLVIO_008292	OG7
TcIL3000_6_1770 ⚠ NUDC-like protein, putative, nuclear movement	—	OG7 TCSYLVIO_005578 ↔ TCSYLVIO_010327	OG7
TcIL3000_7_3480 ⚠ N-terminal conserved domain of Nudc./CS domai	—	OG7 TCSYLVIO_005578 ↔ TCSYLVIO_010327	OG7

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