TcIL3000_10_710

hook complex protein, conserved (fragment)
Trypanosoma congolense IL3000 OG6: OG6_389757 OG7: OG7_0007856 242 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 242 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_0_30110 ⚠
WD domain, G-beta repeat, putative
— OG7
TcIL3000_5_3890 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
TcIL3000_9_1520 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
TcIL3000_10_10910 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_10_13410 ⚠
tRNA pseudouridine synthase A-like protein, p
— OG7
TcIL3000_7_1020 ⚠
pseudouridylate synthase I, putative
— OG7
TcIL3000_6_2460 ⚠
pseudouridine synthase A-like protein, putati
— OG7
TcIL3000_10_2340 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_6_1570 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_13010 ⚠
WD domain, G-beta repeat, putative
— OG7
TcIL3000_0_30260 ⚠
guide RNA associated protein, GAP2
— OG7
TcIL3000_0_21000 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcIL3000_10_10990 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— OG7
TcIL3000_10_11660 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_4_2130 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
TcIL3000_9_1440 ⚠
DNA-damage inducible protein DDI1-like protei
— OG7
TcIL3000.11.6900 ⚠
PUB domain containing protein, putative
— OG7
TcIL3000_0_27090 ⚠
PUB domain containing protein, putative (frag
— OG7
TcIL3000_10_11570 ⚠
PA26 p53-induced protein (sestrin), putative
— OG7
TcIL3000.11.7210 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_44250 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_8_3100 ⚠
coronin, putative (fragment)
— OG7
TcIL3000_7_5890 ⚠
RNA binding protein, putative
— OG7
TcIL3000_0_15160 ⚠
ribonucleoside-diphosphate reductase small ch
— OG7
TcIL3000_0_35830 ⚠
ribonucleoside-diphosphate reductase small ch
— OG7
TcIL3000_1_1430 ⚠
amidohydrolase, putative
— OG7
TcIL3000.11.14420 ⚠
phenylalanyl-tRNA synthetase alpha chain, put
— OG7
TcIL3000.11.2160 ⚠
phenylalanyl-tRNA synthetase, putative
— OG7
TcIL3000.11.7660 ⚠
acidocalcisomal pyrophosphatase
— OG7
TcIL3000_0_38820 ⚠
acidocalcisomal pyrophosphatase
— OG7
TcIL3000.11.13430 ⚠
translation-associated element 2, putative
— OG7
TcIL3000_0_57190 ⚠
translation-associated element 2, putative (f
— OG7
TcIL3000_10_1090 ⚠
Domain of unknown function (DUF4042), putativ
— OG7
TcIL3000_0_05480 ⚠
Domain of unknown function (DUF3441), putativ
— OG7
TcIL3000_10_1100 ⚠
hypothetical protein (fragment)
— OG7
TcIL3000_3_1740 ⚠
inorganic pyrophosphatase, putative
— OG7
TcIL3000_9_1040 ⚠
U6 snRNA-associated Sm-like protein LSm6p, Sm
— OG7
TcIL3000_10_5710 ⚠
ATP-dependent RNA helicase DBP2A, putative
— OG7
TcIL3000_5_4040 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcIL3000_8_1290 ⚠
hypothetical protein
— OG7
TcIL3000_0_57070 ⚠
conserved protein, unknown function
— OG7
TcIL3000_0_00970 ⚠
conserved protein, unknown function
— OG7
TcIL3000_5_4560 ⚠
U6 snRNA-associated Sm-like protein LSm7p, pu
— OG7
TcIL3000_3_880 ⚠
U6 snRNA-associated Sm-like protein LSm8p
— OG7
TcIL3000_0_41370 ⚠
Poly(A)-specific ribonuclease PARN-1
— OG7
TcIL3000_7_5700 ⚠
zinc-finger of a C2HC-type, putative
— OG7
TcIL3000_0_48480 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_9_5730 ⚠
ribonuclease, putative
— OG7
TcIL3000_8_3710 ⚠
mitochondrial, ATP-dependent DEAD/H RNA helic
— OG7
TcIL3000_10_7200 ⚠
ribonuclease, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.