TcIL3000_10_11570

PA26 p53-induced protein (sestrin), putative
Trypanosoma congolense IL3000 OG6: OG6_141922 OG7: OG7_0006056 92 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 92 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_0_49160 ⚠
mitotic centromere-associated kinesin, putati
— OG7
TcIL3000_0_03850 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
TcIL3000_10_13370 ⚠
macrophage infectivity potentiator, precursor
— OG7
TcIL3000_10_8600 ⚠
ubiquitin-protein ligase, putative
— OG7
TcIL3000_9_1140 ⚠
Kinesin-13 1, putative
— OG7
TcIL3000_7_1020 ⚠
pseudouridylate synthase I, putative
— OG7
TcIL3000_0_42730 ⚠
Beige/BEACH domain containing protein, putati
— OG7
TcIL3000.11.3100 ⚠
Kinesin-13 5, putative
— OG7
TcIL3000_6_350 ⚠
pumillio RNA binding protein 4, putative
— OG7
TcIL3000_10_5200 ⚠
neurobeachin/beige protein, putative
— OG7
TcIL3000_0_33830 ⚠
mitotic centromere-associated kinesin, putati
— OG7
TcIL3000_10_710 ⚠
hook complex protein, conserved (fragment)
— OG7
TcIL3000_10_3630 ⚠
pumillo RNA binding protein PUF1, putative
— OG7
TcIL3000_0_32780 ⚠
pumilio/PUF RNA binding protein 5
— OG7
TcIL3000_10_13410 ⚠
tRNA pseudouridine synthase A-like protein, p
— OG7
TcIL3000.11.15490
phosphatidylinositol 3-kinase catalytic subun
— OG7
TcIL3000_0_07970
hypothetical protein, conserved (fragment)
— OG7
TcIL3000_7_5890
RNA binding protein, putative
— OG7
TcIL3000.11.15520 ⚠
Importin subunit beta-4, putative
— OG7
TcIL3000.11.2280 ⚠
metallo-peptidase, Clan MF, Family M17 (fragm
— OG7
TcIL3000_0_24310 ⚠
hypothetical protein (fragment)
— OG7
TcIL3000.11.14030 ⚠
ornithine decarboxylase, putative
— Both
TcIL3000_0_32090 ⚠
ornithine decarboxylase
— Both
TcIL3000_7_2670 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcIL3000_10_6600 ⚠
protein transport protein Sec23A, putative
— OG7
TcIL3000_9_2390 ⚠
RNA pseudouridylate synthase protein, putativ
— OG7
TcIL3000_7_410 ⚠
RNA pseudouridylate synthase, putative
— OG7
TcIL3000_0_48840 ⚠
neurobeachin/beige protein, putative
— OG7
TcIL3000_0_00730 ⚠
neurobeachin/beige protein, putative (fragmen
— OG7
TcIL3000_0_01620 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
TcIL3000_7_1370 ⚠
NF-X1 type zinc finger/R3H domain containing
— OG7
TcIL3000_0_55150 ⚠
ubiquitin-protein ligase, putative (fragment)
— OG7
TcIL3000_10_5210 ⚠
neurobeachin/beige protein, putative (fragmen
— OG7
TcIL3000_9_5670 ⚠
ubiquitin-protein ligase, putative (fragment)
— OG7
TcIL3000_10_2340 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_5_640 ⚠
NADH-dependent fumarate reductase
— Both
TcIL3000_1_1350 ⚠
pumillio RNA binding protein, putative
— OG7
TcIL3000_0_58910 ⚠
hypothetical protein (fragment)
— OG7
TcIL3000_4_3480 ⚠
Kinesin-13 4, putative
— OG7
TcIL3000_10_12710
Hydroxyneurosporene synthase (CrtC)/Polypreny
— OG7
TcIL3000_0_48480
hypothetical protein, conserved
— OG7
TcIL3000_10_13380 ⚠
FKBP-type peptidylprolyl cis-trans isomerase,
— OG7
TcIL3000_10_3830 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcIL3000_10_170 ⚠
pumillio/PUF RNA binding protein 3
— OG7
TcIL3000_0_36120 ⚠
neurobeachin/beige protein, putative
— OG7
TcIL3000.11.4760 ⚠
Kinesin-13 2, putative
— OG7
TcIL3000_5_2800 ⚠
ZPR1 zinc-finger domain containing protein, p
— Both
TcIL3000_0_35650 ⚠
hypothetical protein, conserved
— Both
TcIL3000_0_00610
Ring finger domain containing protein, putati
— OG6
TcIL3000_9_5840
helicase, putative
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.