TcIL3000_7_1020

pseudouridylate synthase I, putative
Trypanosoma congolense IL3000 OG6: OG6_133986 OG7: OG7_0002342 148 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 148 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000.11.2830 ⚠
ribosome assembly protein RRB1, putative
— OG7
TcIL3000_10_710 ⚠
hook complex protein, conserved (fragment)
— OG7
TcIL3000_6_1070 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— OG7
TcIL3000.11.1290 ⚠
zinc-finger of a C2HC-type, putative
— OG7
TcIL3000_5_620 ⚠
NADH-dependent fumarate reductase (fragment)
— OG7
TcIL3000_7_5700 ⚠
zinc-finger of a C2HC-type, putative
— OG7
TcIL3000.11.15850 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_00970 ⚠
conserved protein, unknown function
— OG7
TcIL3000_0_57070 ⚠
conserved protein, unknown function
— OG7
TcIL3000_10_1870 ⚠
Ubiquitin family, putative
— OG7
TcIL3000_6_1480 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcIL3000_4_2130 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
TcIL3000_10_1050 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
TcIL3000_7_5890 ⚠
RNA binding protein, putative
— OG7
TcIL3000_0_30260 ⚠
guide RNA associated protein, GAP2
— OG7
TcIL3000_0_17970 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_53830 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_17980 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_44250 ⚠
hypothetical protein, conserved
— OG7
TcIL3000.11.7210 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_10_11570 ⚠
PA26 p53-induced protein (sestrin), putative
— OG7
TcIL3000_0_42120 ⚠
hypothetical protein, conserved
— OG7
TcIL3000.11.6180 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_9_1440 ⚠
DNA-damage inducible protein DDI1-like protei
— OG7
TcIL3000_0_45720 ⚠
RNA pseudouridylate synthase, putative (fragm
— OG7
TcIL3000_7_410 ⚠
RNA pseudouridylate synthase, putative
— OG7
TcIL3000_0_36000 ⚠
RNA pseudouridylate synthase, putative
— OG7
TcIL3000_9_2390 ⚠
RNA pseudouridylate synthase protein, putativ
— OG7
TcIL3000_8_3580 ⚠
protein transport protein SEC23
— OG7
TcIL3000_10_6600 ⚠
protein transport protein Sec23A, putative
— OG7
TcIL3000.11.11940 ⚠
heat shock 70 kDa protein, putative
— OG7
TcIL3000_0_24310 ⚠
hypothetical protein (fragment)
— OG7
TcIL3000_0_35010 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
TcIL3000.11.7170 ⚠
hypothetical protein (fragment)
— OG7
TcIL3000.11.2280 ⚠
metallo-peptidase, Clan MF, Family M17 (fragm
— OG7
TcIL3000_0_01600 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
TcIL3000_7_3030 ⚠
Bifunctional NAD(P)H-hydrate repair enzyme
— OG7
TcIL3000_0_24550 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_6_4020 ⚠
hypothetical protein, conserved
— OG7
TcIL3000.11.14630 ⚠
Zinc finger, ZZ type, putative
— OG7
TcIL3000_10_8600 ⚠
ubiquitin-protein ligase, putative
— OG7
TcIL3000_6_4160 ⚠
calmodulin, putative
— OG7
TcIL3000_9_5670 ⚠
ubiquitin-protein ligase, putative (fragment)
— OG7
TcIL3000_4_3840 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_55150 ⚠
ubiquitin-protein ligase, putative (fragment)
— OG7
TcIL3000_0_45900 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_1_1430 ⚠
amidohydrolase, putative
— OG7
TcIL3000_4_700 ⚠
V-type ATPase, A subunit, putative
— OG7
TcIL3000_0_35600 ⚠
SPRY domain containing protein, putative
— OG7
TcIL3000_0_24220 ⚠
SPRY domain containing protein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.