TcIL3000_4_700

V-type ATPase, A subunit, putative
Trypanosoma congolense IL3000 OG6: OG6_100902 OG7: OG7_0005426 104 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 104 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000.11.9840
ATP synthase, putative
— Both
TcIL3000.11.12320
Vacuolar proton pump subunit B, putative
— Both
TcIL3000_10_590
ATP synthase, putative
— Both
TcIL3000_0_30260
guide RNA associated protein, GAP2
— Both
TcIL3000_0_55930 ⚠
heat shock 70 kDa protein, putative
— OG6
TcIL3000_0_54460 ⚠
heat shock 70 kDa protein, putative
— OG6
TcIL3000.11.11990 ⚠
luminal binding protein 1 (BiP), putative
— OG6
TcIL3000.11.11940 ⚠
heat shock 70 kDa protein, putative
— Both
TcIL3000.11.11980 ⚠
heat shock protein 70, putative
— OG6
TcIL3000_0_40210 ⚠
heat shock 70 kDa protein, putative (fragment
— OG6
TcIL3000_0_40200 ⚠
heat shock 70 kDa protein, putative
— OG6
TcIL3000_10_3090
vacuolar ATP synthase subunit d, putative
— Both
TcIL3000.11.6820
pyruvate phosphate dikinase
— Both
TcIL3000_0_20480 ⚠
S-adenosyl-L-homocysteine hydrolase/S-adenosy
— Both
TcIL3000.11.10090 ⚠
S-adenosylhomocysteine hydrolase, putative
— Both
TcIL3000_0_20500 ⚠
S-adenosylhomocysteine hydrolase, putative
— Both
TcIL3000.11.10070 ⚠
S-adenosyl-L-homocysteine hydrolase, putative
— Both
TcIL3000_10_50
ATP synthase F1 subunit gamma protein, putati
— Both
TcIL3000_7_1870
Uncharacterised protein family UPF0066, putat
— Both
TcIL3000_0_24220 ⚠
SPRY domain containing protein, putative
— Both
TcIL3000_0_35600 ⚠
SPRY domain containing protein, putative
— Both
TcIL3000_0_45940 ⚠
SPRY domain containing protein, putative
— Both
TcIL3000_10_2660
delta-1-pyrroline-5-carboxylate dehydrogenase
— Both
TcIL3000_9_1440
DNA-damage inducible protein DDI1-like protei
— Both
TcIL3000_6_2160
hypothetical protein, conserved
— Both
TcIL3000.11.16150
hypothetical protein, conserved
— Both
TcIL3000_6_1480 ⚠
aspartyl-tRNA synthetase, putative
— Both
TcIL3000_10_1050 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— Both
TcIL3000_0_06150 ⚠
protein kinase, putative (fragment)
— OG7
TcIL3000_7_5700 ⚠
zinc-finger of a C2HC-type, putative
— OG7
TcIL3000.11.1290 ⚠
zinc-finger of a C2HC-type, putative
— OG7
TcIL3000_0_20550 ⚠
serine/threonine-protein kinase, putative
— OG7
TcIL3000_10_3660 ⚠
leucine carboxyl methyltransferase, putative
— OG7
TcIL3000_10_3720 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
TcIL3000_0_11450 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcIL3000_6_2460 ⚠
pseudouridine synthase A-like protein, putati
— OG7
TcIL3000.11.2930 ⚠
dual-specificity protein kinase, putative
— OG7
TcIL3000_7_1020 ⚠
pseudouridylate synthase I, putative
— OG7
TcIL3000_5_1560 ⚠
serine/threonine-protein kinase, putative, pr
— OG7
TcIL3000_7_3320 ⚠
serine/threonine-protein kinase, putative
— OG7
TcIL3000_0_19190 ⚠
protein kinase, putative (fragment)
— OG7
TcIL3000_10_4080 ⚠
zinc-finger of a C2HC-type, putative
— OG7
TcIL3000_0_38930 ⚠
hexokinase, putative
— Both
TcIL3000.11.3860
N(2), N(2)-dimethylguanosine tRNA methyltrans
— Both
TcIL3000_8_6040 ⚠
tubulin folding cofactor D, putative
— Both
TcIL3000_0_38940 ⚠
hexokinase
— Both
TcIL3000_0_50370 ⚠
tubulin folding cofactor D, putative (fragmen
— Both
TcIL3000_4_2130 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
TcIL3000_10_8720 ⚠
serine/threonine kinase, putative
— OG7
TcIL3000_7_1160 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.