TcIL3000_7_1160

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative
Trypanosoma congolense IL3000 OG6: OG6_132778 OG7: OG7_0002306 166 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 166 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_10_3660 ⚠
leucine carboxyl methyltransferase, putative
— OG7
TcIL3000_9_5290 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— OG7
TcIL3000_0_41040 ⚠
leucine carboxyl methyltransferase, putative
— OG7
TcIL3000_10_9410 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_20550 ⚠
serine/threonine-protein kinase, putative
— OG7
TcIL3000.11.5770 ⚠
synaptojanin (N-terminal domain), putative
— OG7
TcIL3000_0_45560 ⚠
vacuolar sorting-associated protein-like, put
— OG7
TcIL3000_10_4080 ⚠
zinc-finger of a C2HC-type, putative
— OG7
TcIL3000_10_1100 ⚠
hypothetical protein (fragment)
— OG7
TcIL3000_9_4170 ⚠
synaptojanin (N-terminal domain), putative
— OG7
TcIL3000_7_3140 ⚠
protein kinase, putative (fragment)
— OG7
TcIL3000_10_8160 ⚠
branch point binding protein, putative
— OG7
TcIL3000_9_1520 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
TcIL3000.11.9810 ⚠
hypothetical protein
— OG7
TcIL3000_0_47810 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcIL3000_10_520 ⚠
2-oxoisovalerate dehydrogenase alpha subunit,
— OG7
TcIL3000_3_3290 ⚠
Hsc70-interacting protein (Hip), putative
— OG7
TcIL3000_9_3150 ⚠
isopentenyl-diphosphate delta-isomerase (type
— OG7
TcIL3000_0_48690 ⚠
heat shock protein 90, putative
— OG7
TcIL3000_10_710 ⚠
hook complex protein, conserved (fragment)
— OG7
TcIL3000_10_8720 ⚠
serine/threonine kinase, putative
— OG7
TcIL3000_3_1380 ⚠
COP9 signalosome complex subunit 2, putative
— OG7
TcIL3000_0_03820 ⚠
Eukaryotic translation initiation factor 4E-2
— OG7
TcIL3000_10_10910 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_10_210 ⚠
protein kinase, putative
— OG7
TcIL3000_0_06150 ⚠
protein kinase, putative (fragment)
— OG7
TcIL3000_3_2270 ⚠
heat shock protein 90, putative
— OG7
TcIL3000_0_19190 ⚠
protein kinase, putative (fragment)
— OG7
TcIL3000.11.10530 ⚠
vacuolar sorting-associated protein-like, put
— OG7
TcIL3000_10_1090 ⚠
Domain of unknown function (DUF4042), putativ
— OG7
TcIL3000_10_10990 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— OG7
TcIL3000_10_590 ⚠
ATP synthase, putative
— OG7
TcIL3000_10_11660 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_7_3320 ⚠
serine/threonine-protein kinase, putative
— OG7
TcIL3000_5_1560 ⚠
serine/threonine-protein kinase, putative, pr
— OG7
TcIL3000_10_13860 ⚠
zinc-finger of a C2HC-type/Double zinc ribbon
— OG7
TcIL3000_4_420 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
TcIL3000.11.2930 ⚠
dual-specificity protein kinase, putative
— OG7
TcIL3000_0_11450 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcIL3000_0_07850 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
TcIL3000.11.11300 ⚠
Adaptor protein complex AP-3 subunit beta-3
— OG7
TcIL3000_10_1050 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
TcIL3000_10_3710 ⚠
PUB domain containing protein, putative
— OG7
TcIL3000.11.9260 ⚠
leucine rich repeat
— OG7
TcIL3000_0_50450 ⚠
hypothetical protein (fragment)
— OG7
TcIL3000_0_13070 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_10_12230 ⚠
Hsp70 protein, putative
— OG7
TcIL3000.11.5160 ⚠
hypothetical protein, conserved, leucine-rich
— OG7
TcIL3000.11.8260 ⚠
oxidoreductase-like protein
— OG7
TcIL3000_6_3300 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.