TcIL3000_10_3660

leucine carboxyl methyltransferase, putative
Trypanosoma congolense IL3000 OG6: OG6_100931 OG7: OG7_0005126 107 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 107 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_8_600 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
TcIL3000_3_1660 ⚠
6-phosphofructo-2-kinase 1
— OG7
TcIL3000_7_1160 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
TcIL3000_10_3720 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
TcIL3000.11.8260 ⚠
oxidoreductase-like protein
— OG7
TcIL3000_10_9410 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_42090 ⚠
RNA-binding protein 38, putative
— OG7
TcIL3000_10_2980 ⚠
NADH-dependent fumarate reductase
— OG7
TcIL3000.11.9840 ⚠
ATP synthase, putative
— OG7
TcIL3000_5_630 ⚠
NADH-dependent fumarate reductase
— OG7
TcIL3000.11.1290 ⚠
zinc-finger of a C2HC-type, putative
— OG7
TcIL3000_5_620 ⚠
NADH-dependent fumarate reductase (fragment)
— OG7
TcIL3000_7_5700 ⚠
zinc-finger of a C2HC-type, putative
— OG7
TcIL3000_0_15170 ⚠
ubiquitin ligase, putative
— OG7
TcIL3000_0_35850 ⚠
ubiquitin ligase, putative (fragment)
— OG7
TcIL3000_0_18670 ⚠
Leucine Rich Repeat, putative
— OG7
TcIL3000_0_59510 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcIL3000_5_5040 ⚠
Leucine Rich Repeat, putative
— OG7
TcIL3000_10_7930 ⚠
Cyclin 12, L-type
— OG7
TcIL3000_9_4970 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcIL3000_10_3710 ⚠
PUB domain containing protein, putative
— OG7
TcIL3000.11.5160 ⚠
hypothetical protein, conserved, leucine-rich
— OG7
TcIL3000_9_4960 ⚠
Putative death-receptor fusion protein (DUF24
— OG7
TcIL3000_10_7810 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_50450 ⚠
hypothetical protein (fragment)
— OG7
TcIL3000.11.9260 ⚠
leucine rich repeat
— OG7
TcIL3000_0_30260 ⚠
guide RNA associated protein, GAP2
— OG7
TcIL3000_0_44250 ⚠
hypothetical protein, conserved
— OG7
TcIL3000.11.7210 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_9_1440 ⚠
DNA-damage inducible protein DDI1-like protei
— OG7
TcIL3000.11.11940 ⚠
heat shock 70 kDa protein, putative
— OG7
TcIL3000_0_50370 ⚠
tubulin folding cofactor D, putative (fragmen
— OG7
TcIL3000_10_13130 ⚠
hypothetical protein (fragment)
— OG7
TcIL3000_10_13140 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_24190 ⚠
'Cold-shock' DNA-binding domain containing pr
— OG7
TcIL3000_0_09950 ⚠
'Cold-shock' DNA-binding domain containing pr
— OG7
TcIL3000_0_55460 ⚠
'Cold-shock' DNA-binding domain containing pr
— OG7
TcIL3000_0_45960 ⚠
'Cold-shock' DNA-binding domain containing pr
— OG7
TcIL3000_0_46480 ⚠
'Cold-shock' DNA-binding domain containing pr
— OG7
TcIL3000_10_12230 ⚠
Hsp70 protein, putative
— OG7
TcIL3000.11.12040 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_45940 ⚠
SPRY domain containing protein, putative
— OG7
TcIL3000_0_35600 ⚠
SPRY domain containing protein, putative
— OG7
TcIL3000_0_24220 ⚠
SPRY domain containing protein, putative
— OG7
TcIL3000.11.6250 ⚠
RNA-binding protein 38, putative
— OG7
TcIL3000_4_700 ⚠
V-type ATPase, A subunit, putative
— OG7
TcIL3000.11.3320 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_6_4020 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_22360 ⚠
NADH-dependent fumarate reductase
— OG7
TcIL3000_0_00650 ⚠
Inositol hexakisphosphate, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.