TcIL3000.11.11940

heat shock 70 kDa protein, putative

Trypanosoma congolense IL3000 OG6: OG6_100083 OG7: OG7_0000777 167 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 167 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TcIL3000_0_40190 ⚠ heat shock protein 70 (hsp70), putative	—	OG6 Tb927.11.11330 ↔ Tb927.11.7460 OG6 Tb927.11.11330 ↔ Tb927.11.7510 OG6 TCSYLVIO_000724 ↔ TCSYLVIO_010042 OG6 TCSYLVIO_000724 ↔ TCSYLVIO_002291 +1 more	OG6
TcIL3000_0_02950 ⚠ heat shock 70 kDa protein, putative	—	OG6 Tb927.11.11330 ↔ Tb927.11.7460 OG6 Tb927.11.11330 ↔ Tb927.11.7510 OG6 TCSYLVIO_000724 ↔ TCSYLVIO_010042 OG6 TCSYLVIO_000724 ↔ TCSYLVIO_002291 +1 more	OG6
TcIL3000_0_21650 ⚠ Hsp70 protein, putative (fragment)	—	OG6 Tb927.11.11330 ↔ Tb927.11.7460 OG6 Tb927.11.11330 ↔ Tb927.11.7510 OG6 TCSYLVIO_000724 ↔ TCSYLVIO_010042 OG6 TCSYLVIO_000724 ↔ TCSYLVIO_002291 +1 more	OG6
TcIL3000_0_55930 ⚠ heat shock 70 kDa protein, putative	—	OG6 Tb927.11.11330 ↔ Tb927.11.7460 OG6 Tb927.11.11330 ↔ Tb927.11.7510 OG6 TCSYLVIO_000724 ↔ TCSYLVIO_010042 OG6 TCSYLVIO_000724 ↔ TCSYLVIO_002291 +1 more	OG6
TcIL3000_0_54460 ⚠ heat shock 70 kDa protein, putative	—	OG6 Tb927.11.11330 ↔ Tb927.11.7460 OG6 Tb927.11.11330 ↔ Tb927.11.7510 OG6 TCSYLVIO_000724 ↔ TCSYLVIO_010042 OG6 TCSYLVIO_000724 ↔ TCSYLVIO_002291 +1 more	OG6
TcIL3000.11.11990 ⚠ luminal binding protein 1 (BiP), putative	—	OG6 Tb927.11.11330 ↔ Tb927.11.7460 OG6 Tb927.11.11330 ↔ Tb927.11.7510 OG6 TCSYLVIO_000724 ↔ TCSYLVIO_010042 OG6 TCSYLVIO_000724 ↔ TCSYLVIO_002291 +1 more	OG6
TcIL3000_0_27070 ⚠ heat shock 70 kDa protein, putative	—	OG6 Tb927.11.7510 ↔ Tb927.6.3800 OG6 Tb927.11.11330 ↔ Tb927.6.3800 OG6 Tb927.11.7460 ↔ Tb927.6.3740 OG6 Tb927.11.11330 ↔ Tb927.6.3740 +2 more	OG6
TcIL3000_0_08300 ⚠ heat shock 70 kDa protein, putative	—	OG6 Tb927.11.7510 ↔ Tb927.6.3800 OG6 Tb927.11.11330 ↔ Tb927.6.3800 OG6 Tb927.11.7460 ↔ Tb927.6.3740 OG6 Tb927.11.11330 ↔ Tb927.6.3740 +2 more	OG6
TcIL3000_0_40200 ⚠ heat shock 70 kDa protein, putative	—	OG6 Tb927.11.11330 ↔ Tb927.11.7460 OG6 Tb927.11.11330 ↔ Tb927.11.7510 OG6 TCSYLVIO_000724 ↔ TCSYLVIO_010042 OG6 TCSYLVIO_000724 ↔ TCSYLVIO_002291 +1 more	OG6
TcIL3000.11.11980 ⚠ heat shock protein 70, putative	—	OG6 Tb927.11.11330 ↔ Tb927.11.7460 OG6 Tb927.11.11330 ↔ Tb927.11.7510 OG6 TCSYLVIO_000724 ↔ TCSYLVIO_010042 OG6 TCSYLVIO_000724 ↔ TCSYLVIO_002291 +1 more	OG6
TcIL3000_0_40210 ⚠ heat shock 70 kDa protein, putative (fragment	—	OG6 Tb927.11.11330 ↔ Tb927.11.7460 OG6 Tb927.11.11330 ↔ Tb927.11.7510 OG6 TCSYLVIO_000724 ↔ TCSYLVIO_010042 OG6 TCSYLVIO_000724 ↔ TCSYLVIO_002291 +1 more	OG6
TcIL3000_10_5570 ⚠ TCP-1/cpn60 chaperonin family, putative	—	OG6 Tb927.10.6400 ↔ Tb927.11.11330	OG6
TcIL3000_6_2160 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_002696 ↔ TCSYLVIO_003179 OG7 TCSYLVIO_002696 ↔ TCSYLVIO_003179	Both
TcIL3000_0_31250 ⚠ Tubulin/FtsZ family, GTPase domain containing	—	OG6 TCSYLVIO_002291 ↔ TCSYLVIO_008641 OG6 TCSYLVIO_002291 ↔ TCSYLVIO_008204	OG6
TcIL3000.11.2830 ⚠ ribosome assembly protein RRB1, putative	—	OG6 TCSYLVIO_002696 ↔ TCSYLVIO_005619 OG7 TCSYLVIO_002696 ↔ TCSYLVIO_005619	Both
TcIL3000_10_13860 ⚠ zinc-finger of a C2HC-type/Double zinc ribbon	—	OG6 TCSYLVIO_002696 ↔ TCSYLVIO_006138 OG7 TCSYLVIO_002696 ↔ TCSYLVIO_006138	Both
TcIL3000.11.3860 ⚠ N(2), N(2)-dimethylguanosine tRNA methyltrans	—	OG6 TCSYLVIO_002696 ↔ TCSYLVIO_002844 OG7 TCSYLVIO_002696 ↔ TCSYLVIO_002844	Both
TcIL3000_9_2550 ⚠ hypothetical protein	—	OG6 TCSYLVIO_002696 ↔ TCSYLVIO_007342	OG6
TcIL3000_0_54930 ⚠ cysteine peptidase, Clan CA, family C2, putat	—	OG6 TCSYLVIO_002696 ↔ TCSYLVIO_007342	OG6
TcIL3000_10_2340 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_002696 ↔ TCSYLVIO_004376 OG7 TCSYLVIO_002696 ↔ TCSYLVIO_004376	Both
TcIL3000_10_1050 ⚠ OB-fold nucleic acid binding domain/tRNA synt	—	OG6 TCSYLVIO_002696 ↔ TCSYLVIO_003107 OG7 TCSYLVIO_002696 ↔ TCSYLVIO_003107	Both
TcIL3000_10_2980 ⚠ NADH-dependent fumarate reductase	—	OG6 TCSYLVIO_002696 ↔ TCSYLVIO_005116 OG6 TCSYLVIO_002696 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_002696 ↔ TCSYLVIO_005116 OG7 TCSYLVIO_002696 ↔ TCSYLVIO_008502	Both
TcIL3000_0_41040 ⚠ leucine carboxyl methyltransferase, putative	—	OG6 TCSYLVIO_002696 ↔ TCSYLVIO_005852 OG7 TCSYLVIO_002696 ↔ TCSYLVIO_005852	Both
TcIL3000_10_8740 ⚠ paraflagellar rod component, putative	—	OG6 TCSYLVIO_002696 ↔ TCSYLVIO_004736 OG7 TCSYLVIO_002696 ↔ TCSYLVIO_004736	Both
TcIL3000.11.9840 ⚠ ATP synthase, putative	—	OG6 TCSYLVIO_002696 ↔ TCSYLVIO_009199 OG7 TCSYLVIO_002696 ↔ TCSYLVIO_009199	Both
TcIL3000_0_35600 ⚠ SPRY domain containing protein, putative	—	OG6 TCSYLVIO_002696 ↔ TCSYLVIO_002919 OG7 TCSYLVIO_002696 ↔ TCSYLVIO_002919	Both
TcIL3000_5_630 ⚠ NADH-dependent fumarate reductase	—	OG6 TCSYLVIO_002696 ↔ TCSYLVIO_005116 OG6 TCSYLVIO_002696 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_002696 ↔ TCSYLVIO_005116 OG7 TCSYLVIO_002696 ↔ TCSYLVIO_008502	Both
TcIL3000_0_27270 ⚠ alpha tubulin	—	OG6 TCSYLVIO_002291 ↔ TCSYLVIO_008641 OG6 TCSYLVIO_002291 ↔ TCSYLVIO_008204	OG6
TcIL3000_5_620 ⚠ NADH-dependent fumarate reductase (fragment)	—	OG6 TCSYLVIO_002696 ↔ TCSYLVIO_005116 OG6 TCSYLVIO_002696 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_002696 ↔ TCSYLVIO_005116 OG7 TCSYLVIO_002696 ↔ TCSYLVIO_008502	Both
TcIL3000_0_04440 ⚠ asparagine synthetase a, putative	—	OG6 TCSYLVIO_002194 ↔ TCSYLVIO_002332	OG6
TcIL3000_0_22360 ⚠ NADH-dependent fumarate reductase	—	OG6 TCSYLVIO_002696 ↔ TCSYLVIO_005116 OG6 TCSYLVIO_002696 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_002696 ↔ TCSYLVIO_005116 OG7 TCSYLVIO_002696 ↔ TCSYLVIO_008502	Both
TcIL3000_3_3560 ⚠ Metallopeptidase family M24/FACT complex subu	—	OG6 TCSYLVIO_002696 ↔ TCSYLVIO_010728 OG7 TCSYLVIO_002696 ↔ TCSYLVIO_010728	Both
TcIL3000_9_2560 ⚠ cysteine peptidase, Clan CA, family C2, putat	—	OG6 TCSYLVIO_002696 ↔ TCSYLVIO_007342	OG6
TcIL3000_6_4020 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_002696 ↔ TCSYLVIO_003353 OG7 TCSYLVIO_002696 ↔ TCSYLVIO_003353	Both
TcIL3000_9_1440 ⚠ DNA-damage inducible protein DDI1-like protei	—	OG6 TCSYLVIO_002696 ↔ TCSYLVIO_003428 OG7 TCSYLVIO_002696 ↔ TCSYLVIO_003428	Both
TcIL3000_6_1350 ⚠ kinesin, putative	—	OG6 TCSYLVIO_002696 ↔ TCSYLVIO_003093	OG6
TcIL3000_0_45940 ⚠ SPRY domain containing protein, putative	—	OG6 TCSYLVIO_002696 ↔ TCSYLVIO_002919 OG7 TCSYLVIO_002696 ↔ TCSYLVIO_002919	Both
TcIL3000_5_640 ⚠ NADH-dependent fumarate reductase	—	OG6 TCSYLVIO_002696 ↔ TCSYLVIO_005116 OG6 TCSYLVIO_002696 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_002696 ↔ TCSYLVIO_005116 OG7 TCSYLVIO_002696 ↔ TCSYLVIO_008502	Both
TcIL3000_9_5290 ⚠ Leucine carboxyl methyltransferase/Cupin-like	—	OG6 TCSYLVIO_002696 ↔ TCSYLVIO_005852 OG7 TCSYLVIO_002696 ↔ TCSYLVIO_005852	Both
TcIL3000.11.16230 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_002696 ↔ TCSYLVIO_005357 OG7 TCSYLVIO_002696 ↔ TCSYLVIO_005357	Both
TcIL3000_9_1350 ⚠ fatty acyl CoA synthetase 4, putative	—	OG6 LdBPK_010510.1 ↔ LdBPK_281310.1	OG6
TcIL3000_9_1330 ⚠ fatty acyl CoA synthetase 2, putative	—	OG6 LdBPK_010510.1 ↔ LdBPK_281310.1	OG6
TcIL3000_10_2700 ⚠ Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1	—	OG6 LdBPK_010510.1 ↔ LdBPK_281310.1	OG6
TcIL3000_9_1300 ⚠ Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1	—	OG6 LdBPK_010510.1 ↔ LdBPK_281310.1	OG6
TcIL3000_9_1310 ⚠ hypothetical protein (fragment)	—	OG6 LdBPK_010510.1 ↔ LdBPK_281310.1	OG6
TcIL3000_0_13330 ⚠ ribosomal RNA processing protein 4	—	OG6 Tb927.7.4670 ↔ Tb927.7.710	OG6
TcIL3000_3_380 ⚠ Conserved hypothetical ATP binding protein, p	—	OG6 Tb927.3.1150 ↔ Tb927.7.710	OG6
TcIL3000_7_1870 ⚠ Uncharacterised protein family UPF0066, putat	—	OG6 TCSYLVIO_001255 ↔ TCSYLVIO_002696 OG7 TCSYLVIO_001255 ↔ TCSYLVIO_002696	Both
TcIL3000_8_2710 ⚠ acetyl-CoA synthetase, putative	—	OG6 TCSYLVIO_000046 ↔ TCSYLVIO_002194	OG6
TcIL3000_7_3320 ⚠ serine/threonine-protein kinase, putative	—	OG7 TCSYLVIO_002696 ↔ TCSYLVIO_009362	OG7

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