TcIL3000_10_8740

paraflagellar rod component, putative

Trypanosoma congolense IL3000 OG6: OG6_110710 OG7: OG7_0006349 162 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 162 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TcIL3000_8_600 ⚠ 6-phosphofructo-2-kinase/fructose-2,6-biphosp	—	OG6 TCSYLVIO_004468 ↔ TCSYLVIO_004736 OG6 LdBPK_030790.1 ↔ LdBPK_364440.1 OG7 TCSYLVIO_002376 ↔ TCSYLVIO_004736 OG7 TCSYLVIO_004468 ↔ TCSYLVIO_004736	Both
TcIL3000_3_1660 ⚠ 6-phosphofructo-2-kinase 1	—	OG6 TCSYLVIO_004468 ↔ TCSYLVIO_004736 OG6 LdBPK_030790.1 ↔ LdBPK_364440.1 OG7 TCSYLVIO_002376 ↔ TCSYLVIO_004736 OG7 TCSYLVIO_004468 ↔ TCSYLVIO_004736	Both
TcIL3000_9_5290 ⚠ Leucine carboxyl methyltransferase/Cupin-like	—	OG6 LdBPK_352990.1 ↔ LdBPK_364440.1 OG6 TCSYLVIO_004736 ↔ TCSYLVIO_005852 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_005852	Both
TcIL3000_0_41040 ⚠ leucine carboxyl methyltransferase, putative	—	OG6 LdBPK_352990.1 ↔ LdBPK_364440.1 OG6 TCSYLVIO_004736 ↔ TCSYLVIO_005852 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_005852	Both
TcIL3000.11.2160 phenylalanyl-tRNA synthetase, putative	—	OG6 LdBPK_191010.1 ↔ LdBPK_364440.1 OG6 TCSYLVIO_004736 ↔ TCSYLVIO_005548 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_005548	Both
TcIL3000_10_12750 ⚠ C-terminal motor kinesin, putative (fragment)	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_006065	OG6
TcIL3000_5_3890 ⚠ ubiquitin-activating enzyme E1, putative	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_010542 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_010542	Both
TcIL3000_10_12760 ⚠ C-terminal motor kinesin, putative (fragment)	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_006065	OG6
TcIL3000.11.1710 hypothetical protein, conserved	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_005512 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_005512	Both
TcIL3000_0_18970 ⚠ cysteine peptidase, Clan CA, family C2, putat	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_007342	OG6
TcIL3000_5_860 threonyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_007511 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_007511	Both
TcIL3000_10_520 2-oxoisovalerate dehydrogenase alpha subunit,	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_009339 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_009339	Both
TcIL3000_3_3290 Hsc70-interacting protein (Hip), putative	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_010703 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_010703	Both
TcIL3000_10_3090 vacuolar ATP synthase subunit d, putative	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_005104 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_005104	Both
TcIL3000_3_1380 COP9 signalosome complex subunit 2, putative	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_006413 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_006413	Both
TcIL3000_0_21000 ⚠ hypothetical protein, conserved (fragment)	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_010560 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_010560	Both
TcIL3000_8_2210 pteridine reductase 1	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_008848 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_008848	Both
TcIL3000_10_11830 ATP12 chaperone protein, putative	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_006163 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_006163	Both
TcIL3000_10_210 ⚠ protein kinase, putative	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_009362 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_009362	Both
TcIL3000_10_10910 hypothetical protein, conserved	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_006238 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_006238	Both
TcIL3000_0_49940 exonuclease, putative	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_010944 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_010944	Both
TcIL3000_1_420 ⚠ developmentally regulated phosphoprotein, put	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_004736	Both
TcIL3000_0_15170 ⚠ ubiquitin ligase, putative	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_006542 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_006542	Both
TcIL3000.11.16020 ⚠ ubiquitin carboxyl-terminal hydrolase, putati	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_005374 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_005374	Both
TcIL3000_10_10990 bifunctional aminoacyl-tRNA synthetase, putat	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_006246 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_006246	Both
TcIL3000_10_590 ATP synthase, putative	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_009332 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_009332	Both
TcIL3000_10_11660 hypothetical protein, conserved	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_006181 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_006181	Both
TcIL3000.11.2830 ⚠ ribosome assembly protein RRB1, putative	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_005619 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_005619	Both
TcIL3000_10_13860 ⚠ zinc-finger of a C2HC-type/Double zinc ribbon	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_006138 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_006138	Both
TcIL3000_9_2550 ⚠ hypothetical protein	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_007342	OG6
TcIL3000_0_54930 ⚠ cysteine peptidase, Clan CA, family C2, putat	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_007342	OG6
TcIL3000_0_13010 ⚠ WD domain, G-beta repeat, putative	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_010560 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_010560	Both
TcIL3000_10_2980 ⚠ NADH-dependent fumarate reductase	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_005116 OG6 TCSYLVIO_004736 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_004736 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_005116 +2 more	Both
TcIL3000.11.9840 ATP synthase, putative	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_009199 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_009199	Both
TcIL3000_0_26120 ⚠ Hsp90 protein, putative (fragment)	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_004736 ↔ TCSYLVIO_009400 OG6 TCSYLVIO_004736 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_008621 +2 more	Both
TcIL3000_5_630 ⚠ NADH-dependent fumarate reductase	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_005116 OG6 TCSYLVIO_004736 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_004736 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_005116 +2 more	Both
TcIL3000.11.9820 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_009198 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_009198	Both
TcIL3000_5_620 ⚠ NADH-dependent fumarate reductase (fragment)	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_005116 OG6 TCSYLVIO_004736 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_004736 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_005116 +2 more	Both
TcIL3000_0_35850 ⚠ ubiquitin ligase, putative (fragment)	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_006542 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_006542	Both
TcIL3000_0_22360 ⚠ NADH-dependent fumarate reductase	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_005116 OG6 TCSYLVIO_004736 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_004736 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_005116 +2 more	Both
TcIL3000_3_3560 Metallopeptidase family M24/FACT complex subu	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_010728 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_010728	Both
TcIL3000_9_2560 ⚠ cysteine peptidase, Clan CA, family C2, putat	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_007342	OG6
TcIL3000_0_28240 cysteinyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_006977 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_006977	Both
TcIL3000.11.2930 ⚠ dual-specificity protein kinase, putative	—	OG7 TCSYLVIO_004736 ↔ TCSYLVIO_009362	OG7
TcIL3000.11.2400 ⚠ heat shock protein, mitochondrial precursor,	—	OG7 TCSYLVIO_004736 ↔ TCSYLVIO_008621 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_009400 OG7 TCSYLVIO_004736 ↔ TCSYLVIO_009151	OG7
TcIL3000_0_20550 ⚠ serine/threonine-protein kinase, putative	—	OG7 TCSYLVIO_004736 ↔ TCSYLVIO_009362	OG7
TcIL3000_9_1900 ⚠ inositol/phosphatidylinositol phosphatase, pu	—	OG7 TCSYLVIO_004736 ↔ TCSYLVIO_007569	OG7
TcIL3000_10_3660 ⚠ leucine carboxyl methyltransferase, putative	—	OG7 TCSYLVIO_004736 ↔ TCSYLVIO_005852	OG7
TcIL3000_0_11450 ⚠ hypothetical protein, conserved (fragment)	—	OG7 TCSYLVIO_004736 ↔ TCSYLVIO_006138	OG7
TcIL3000_5_1560 ⚠ serine/threonine-protein kinase, putative, pr	—	OG7 TCSYLVIO_004736 ↔ TCSYLVIO_009362	OG7

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