TcIL3000_3_3560

Metallopeptidase family M24/FACT complex subunit (SPT16/CDC68)/Histone chaperone Rttp106-like, putative
Trypanosoma congolense IL3000 OG6: OG6_102309 OG7: OG7_0007246 150 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 150 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_5_3890 ⚠
ubiquitin-activating enzyme E1, putative
— Both
TcIL3000_6_1820
hypothetical protein, conserved
— Both
TcIL3000_7_1870
Uncharacterised protein family UPF0066, putat
— Both
TcIL3000_0_24220 ⚠
SPRY domain containing protein, putative
— Both
TcIL3000_0_32610 ⚠
ribonucleoprotein p18, mitochondrial precurso
— Both
TcIL3000_0_35600 ⚠
SPRY domain containing protein, putative
— Both
TcIL3000_5_1650 ⚠
ribonucleoprotein p18, mitochondrial precurso
— Both
TcIL3000_0_45940 ⚠
SPRY domain containing protein, putative
— Both
TcIL3000_0_26120 ⚠
Hsp90 protein, putative (fragment)
— +2 more Both
TcIL3000_0_26140 ⚠
Heat shock protein 83, putative
— +2 more Both
TcIL3000_0_26130 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— +2 more Both
TcIL3000_9_1440
DNA-damage inducible protein DDI1-like protei
— Both
TcIL3000_8_6190 ⚠
WD domain, G-beta repeat, putative (fragment)
— Both
TcIL3000_0_44870 ⚠
PFU (PLAA family ubiquitin binding), putative
— Both
TcIL3000_6_2160
hypothetical protein, conserved
— Both
TcIL3000_10_12240
Histone chaperone Rttp106-like, putative
— Both
TcIL3000_1_420 ⚠
developmentally regulated phosphoprotein, put
— Both
TcIL3000.11.9820 ⚠
hypothetical protein, conserved
— Both
TcIL3000_10_210 ⚠
protein kinase, putative
— Both
TcIL3000_6_1480 ⚠
aspartyl-tRNA synthetase, putative
— Both
TcIL3000_10_1050 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— Both
TcIL3000_0_41370 ⚠
Poly(A)-specific ribonuclease PARN-1
— Both
TcIL3000_10_7200 ⚠
ribonuclease, putative
— Both
TcIL3000_0_30260
guide RNA associated protein, GAP2
— Both
TcIL3000_0_15170 ⚠
ubiquitin ligase, putative
— Both
TcIL3000_0_35850 ⚠
ubiquitin ligase, putative (fragment)
— Both
TcIL3000_9_770 ⚠
hypothetical protein (fragment)
— Both
TcIL3000_8_4490 ⚠
hypothetical protein, conserved
— Both
TcIL3000_9_760 ⚠
hypothetical protein, conserved
— Both
TcIL3000.11.3860
N(2), N(2)-dimethylguanosine tRNA methyltrans
— Both
TcIL3000_6_1570
hypothetical protein, conserved
— Both
TcIL3000_8_6040 ⚠
tubulin folding cofactor D, putative
— Both
TcIL3000_0_50370 ⚠
tubulin folding cofactor D, putative (fragmen
— Both
TcIL3000_3_1740 ⚠
inorganic pyrophosphatase, putative
— Both
TcIL3000_0_38820 ⚠
acidocalcisomal pyrophosphatase
— Both
TcIL3000.11.7660 ⚠
acidocalcisomal pyrophosphatase
— Both
TcIL3000_10_3090
vacuolar ATP synthase subunit d, putative
— Both
TcIL3000_10_8740
paraflagellar rod component, putative
— Both
TcIL3000_5_1560 ⚠
serine/threonine-protein kinase, putative, pr
— OG7
TcIL3000.11.9810 ⚠
hypothetical protein
— OG7
TcIL3000_0_36870 ⚠
Paraflagellar Rod Proteome Component 9, putat
— OG7
TcIL3000_10_3660 ⚠
leucine carboxyl methyltransferase, putative
— OG7
TcIL3000_4_420 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
TcIL3000_7_3140 ⚠
protein kinase, putative (fragment)
— OG7
TcIL3000_10_8720 ⚠
serine/threonine kinase, putative
— OG7
TcIL3000_0_06150 ⚠
protein kinase, putative (fragment)
— OG7
TcIL3000_0_19190 ⚠
protein kinase, putative (fragment)
— OG7
TcIL3000_7_3320 ⚠
serine/threonine-protein kinase, putative
— OG7
TcIL3000_0_26160 ⚠
Adaptor protein complex AP-3 subunit beta-3
— OG7
TcIL3000.11.2400 ⚠
heat shock protein, mitochondrial precursor,
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.