TcIL3000_6_1820

hypothetical protein, conserved
Trypanosoma congolense IL3000 OG6: OG6_113914 OG7: OG7_0021257 148 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 148 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_0_35010 ⚠
metallo-peptidase, Clan MF, Family M17
— Both
TcIL3000.11.7170 ⚠
hypothetical protein (fragment)
— Both
TcIL3000_0_22370 ⚠
NADH-dependent fumarate reductase
— +2 more Both
TcIL3000_10_2980 ⚠
NADH-dependent fumarate reductase
— +2 more Both
TcIL3000_5_630 ⚠
NADH-dependent fumarate reductase
— +2 more Both
TcIL3000_5_620 ⚠
NADH-dependent fumarate reductase (fragment)
— +2 more Both
TcIL3000_0_22360 ⚠
NADH-dependent fumarate reductase
— +2 more Both
TcIL3000_5_640 ⚠
NADH-dependent fumarate reductase
— +2 more Both
TcIL3000.11.2280 ⚠
metallo-peptidase, Clan MF, Family M17 (fragm
— OG7
TcIL3000_0_24310 ⚠
hypothetical protein (fragment)
— OG7
TcIL3000_0_45720 ⚠
RNA pseudouridylate synthase, putative (fragm
— Both
TcIL3000_10_12710
Hydroxyneurosporene synthase (CrtC)/Polypreny
— OG7
TcIL3000_0_36000 ⚠
RNA pseudouridylate synthase, putative
— Both
TcIL3000_1_1080 ⚠
cyclophilin 15, putative
— Both
TcIL3000_0_54360 ⚠
cyclophilin 15, putative
— Both
TcIL3000_0_32610 ⚠
ribonucleoprotein p18, mitochondrial precurso
— Both
TcIL3000_5_1650 ⚠
ribonucleoprotein p18, mitochondrial precurso
— Both
TcIL3000_10_11570
PA26 p53-induced protein (sestrin), putative
— Both
TcIL3000_8_6190 ⚠
WD domain, G-beta repeat, putative (fragment)
— Both
TcIL3000_0_44870 ⚠
PFU (PLAA family ubiquitin binding), putative
— Both
TcIL3000_0_43000 ⚠
hypothetical protein, conserved
— Both
TcIL3000_7_2090 ⚠
hypothetical protein, conserved
— Both
TcIL3000_0_41370 ⚠
Poly(A)-specific ribonuclease PARN-1
— Both
TcIL3000_10_7200 ⚠
ribonuclease, putative
— Both
TcIL3000_3_3580 ⚠
nuclear transcription factor, putative
— Both
TcIL3000_6_1570
hypothetical protein, conserved
— Both
TcIL3000_8_6040 ⚠
tubulin folding cofactor D, putative
— Both
TcIL3000_0_50370 ⚠
tubulin folding cofactor D, putative (fragmen
— Both
TcIL3000_3_1740 ⚠
inorganic pyrophosphatase, putative
— Both
TcIL3000_0_38820 ⚠
acidocalcisomal pyrophosphatase
— Both
TcIL3000.11.7660 ⚠
acidocalcisomal pyrophosphatase
— Both
TcIL3000_0_00970 ⚠
conserved protein, unknown function
— Both
TcIL3000_0_32090 ⚠
ornithine decarboxylase
— Both
TcIL3000_0_57070 ⚠
conserved protein, unknown function
— Both
TcIL3000.11.14030 ⚠
ornithine decarboxylase, putative
— Both
TcIL3000.11.15490
phosphatidylinositol 3-kinase catalytic subun
— OG7
TcIL3000_10_13410 ⚠
tRNA pseudouridine synthase A-like protein, p
— OG7
TcIL3000_10_5200 ⚠
neurobeachin/beige protein, putative
— OG7
TcIL3000_0_42730 ⚠
Beige/BEACH domain containing protein, putati
— OG7
TcIL3000_7_1020 ⚠
pseudouridylate synthase I, putative
— OG7
TcIL3000_0_36120 ⚠
neurobeachin/beige protein, putative
— OG7
TcIL3000_10_2340 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_10_5210 ⚠
neurobeachin/beige protein, putative (fragmen
— OG7
TcIL3000_0_01620 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
TcIL3000_10_3720 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
TcIL3000_7_410 ⚠
RNA pseudouridylate synthase, putative
— OG7
TcIL3000_7_5890
RNA binding protein, putative
— OG7
TcIL3000_7_1370 ⚠
NF-X1 type zinc finger/R3H domain containing
— OG7
TcIL3000_9_5730 ⚠
ribonuclease, putative
— OG7
TcIL3000_8_600 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.