TcIL3000_0_44870

PFU (PLAA family ubiquitin binding), putative
Trypanosoma congolense IL3000 OG6: OG6_101801 OG7: OG7_0006699 112 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 112 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_8_600 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
TcIL3000_0_38820 ⚠
acidocalcisomal pyrophosphatase
— Both
TcIL3000.11.7170 ⚠
hypothetical protein (fragment)
— Both
TcIL3000_10_12240 ⚠
Histone chaperone Rttp106-like, putative
— Both
TcIL3000_10_12750 ⚠
C-terminal motor kinesin, putative (fragment)
— OG6
TcIL3000_9_1440 ⚠
DNA-damage inducible protein DDI1-like protei
— Both
TcIL3000_6_1350 ⚠
kinesin, putative
— OG6
TcIL3000_10_6020 ⚠
hypothetical protein, conserved
— Both
TcIL3000_7_810 ⚠
hypothetical protein, conserved (fragment)
— Both
TcIL3000.11.4250 ⚠
mannose-specific lectin, putative
— Both
TcIL3000_0_26140 ⚠
Heat shock protein 83, putative
— +2 more Both
TcIL3000_0_26130 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— +2 more Both
TcIL3000_5_640 ⚠
NADH-dependent fumarate reductase
— Both
TcIL3000_5_4970 ⚠
dihydrolipoamide branched chain transacylase,
— Both
TcIL3000.11.7660 ⚠
acidocalcisomal pyrophosphatase
— Both
TcIL3000_9_4940 ⚠
hypothetical protein, conserved
— Both
TcIL3000_10_13170 ⚠
Flagellum attachment zone protein 7
— OG6
TcIL3000.11.14420 ⚠
phenylalanyl-tRNA synthetase alpha chain, put
— Both
TcIL3000_0_41370 ⚠
Poly(A)-specific ribonuclease PARN-1
— Both
TcIL3000_10_7200 ⚠
ribonuclease, putative
— Both
TcIL3000_8_6040 ⚠
tubulin folding cofactor D, putative
— Both
TcIL3000_0_50370 ⚠
tubulin folding cofactor D, putative (fragmen
— Both
TcIL3000_9_5730 ⚠
ribonuclease, putative
— OG7
TcIL3000_0_24310 ⚠
hypothetical protein (fragment)
— OG7
TcIL3000_0_26160 ⚠
Adaptor protein complex AP-3 subunit beta-3
— OG7
TcIL3000_6_1480 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcIL3000.11.5770 ⚠
synaptojanin (N-terminal domain), putative
— OG7
TcIL3000_9_4170 ⚠
synaptojanin (N-terminal domain), putative
— OG7
TcIL3000_0_10490 ⚠
serine/threonine protein kinase, putative
— OG7
TcIL3000.11.2280 ⚠
metallo-peptidase, Clan MF, Family M17 (fragm
— OG7
TcIL3000_7_5060 ⚠
protein kinase, putative
— OG7
TcIL3000_10_4640 ⚠
endonuclease/exonuclease/phosphatase, putativ
— OG7
TcIL3000_0_32980 ⚠
protein kinase, putative
— OG7
TcIL3000.11.2400 ⚠
heat shock protein, mitochondrial precursor,
— OG7
TcIL3000_9_1900 ⚠
inositol/phosphatidylinositol phosphatase, pu
— OG7
TcIL3000_10_1050 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
TcIL3000.11.11300 ⚠
Adaptor protein complex AP-3 subunit beta-3
— OG7
TcIL3000_10_3720 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
TcIL3000_10_7260 ⚠
legume-like lectin, putative
— OG7
TcIL3000_4_420 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
TcIL3000_0_30150 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcIL3000_2_870 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcIL3000_10_710 ⚠
hook complex protein, conserved (fragment)
— OG7
TcIL3000_3_1660 ⚠
6-phosphofructo-2-kinase 1
— OG7
TcIL3000_9_1520 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
TcIL3000.11.9810 ⚠
hypothetical protein
— OG7
TcIL3000_2_1340 ⚠
protein kinase, putative
— OG7
TcIL3000_0_47810 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcIL3000_0_48690 ⚠
heat shock protein 90, putative
— OG7
TcIL3000_10_13090 ⚠
protein kinase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.