TcIL3000_9_1440

DNA-damage inducible protein DDI1-like protein

Trypanosoma congolense IL3000 OG6: OG6_101685 OG7: OG7_0006273 223 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 223 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TcIL3000.11.7170 ⚠ hypothetical protein (fragment)	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_003428 OG6 LdBPK_010630.1 ↔ LdBPK_110630.1 OG6 LdBPK_010630.1 ↔ LdBPK_110640.1 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003428 +3 more	Both
TcIL3000_0_35010 ⚠ metallo-peptidase, Clan MF, Family M17	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_003428 OG6 LdBPK_010630.1 ↔ LdBPK_110630.1 OG6 LdBPK_010630.1 ↔ LdBPK_110640.1 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003428 +3 more	Both
TcIL3000.11.2280 ⚠ metallo-peptidase, Clan MF, Family M17 (fragm	—	OG6 LdBPK_010630.1 ↔ LdBPK_332700.1 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003428 OG7 LdBPK_010630.1 ↔ LdBPK_110630.1 OG7 LdBPK_010630.1 ↔ LdBPK_332700.1 +1 more	Both
TcIL3000_0_24310 ⚠ hypothetical protein (fragment)	—	OG6 LdBPK_010630.1 ↔ LdBPK_332700.1 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003428 OG7 LdBPK_010630.1 ↔ LdBPK_110630.1 OG7 LdBPK_010630.1 ↔ LdBPK_332700.1 +1 more	Both
TcIL3000_0_08150 ⚠ CYC2-like cyclin, putative	—	OG7 LdBPK_010630.1 ↔ LdBPK_241960.1	OG7
TcIL3000_10_10990 bifunctional aminoacyl-tRNA synthetase, putat	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_006246 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_006246	Both
TcIL3000_9_5730 ⚠ ribonuclease, putative	—	OG7 TCSYLVIO_000055 ↔ TCSYLVIO_003428	OG7
TcIL3000_10_3720 ⚠ 6-phosphofructo-2-kinase/fructose-2,6-bisphos	—	OG7 TCSYLVIO_002376 ↔ TCSYLVIO_003428 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_004468	OG7
TcIL3000.11.7660 ⚠ acidocalcisomal pyrophosphatase	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_003428 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_003428	Both
TcIL3000_0_38820 ⚠ acidocalcisomal pyrophosphatase	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_003428 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_003428	Both
TcIL3000_3_1740 ⚠ inorganic pyrophosphatase, putative	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_003428 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_003428	Both
TcIL3000_0_50370 ⚠ tubulin folding cofactor D, putative (fragmen	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_003428 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_003428	Both
TcIL3000_8_6040 ⚠ tubulin folding cofactor D, putative	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_003428 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_003428	Both
TcIL3000_6_1570 hypothetical protein, conserved	—	OG6 TCSYLVIO_003118 ↔ TCSYLVIO_003428 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_003428	Both
TcIL3000.11.3860 N(2), N(2)-dimethylguanosine tRNA methyltrans	—	OG6 TCSYLVIO_002844 ↔ TCSYLVIO_003428 OG7 TCSYLVIO_002844 ↔ TCSYLVIO_003428	Both
TcIL3000_0_30260 guide RNA associated protein, GAP2	—	OG6 TCSYLVIO_001262 ↔ TCSYLVIO_003428 OG7 TCSYLVIO_001262 ↔ TCSYLVIO_003428	Both
TcIL3000_10_7200 ⚠ ribonuclease, putative	—	OG6 TCSYLVIO_000055 ↔ TCSYLVIO_003428 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_003428	Both
TcIL3000_0_41370 ⚠ Poly(A)-specific ribonuclease PARN-1	—	OG6 TCSYLVIO_000055 ↔ TCSYLVIO_003428 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_003428	Both
TcIL3000_10_1050 ⚠ OB-fold nucleic acid binding domain/tRNA synt	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_003428 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_003428 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_003867	Both
TcIL3000_6_1480 ⚠ aspartyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_003428 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_003428 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_003867	Both
TcIL3000_6_2160 hypothetical protein, conserved	—	OG6 TCSYLVIO_003179 ↔ TCSYLVIO_003428 OG7 TCSYLVIO_003179 ↔ TCSYLVIO_003428	Both
TcIL3000_0_44870 ⚠ PFU (PLAA family ubiquitin binding), putative	—	OG6 TCSYLVIO_001314 ↔ TCSYLVIO_003428 OG7 TCSYLVIO_001314 ↔ TCSYLVIO_003428	Both
TcIL3000_8_6190 ⚠ WD domain, G-beta repeat, putative (fragment)	—	OG6 TCSYLVIO_001314 ↔ TCSYLVIO_003428 OG7 TCSYLVIO_001314 ↔ TCSYLVIO_003428	Both
TcIL3000.11.14420 phenylalanyl-tRNA synthetase alpha chain, put	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_004213 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_004213	Both
TcIL3000_9_4940 hypothetical protein, conserved	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_005810 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_005810	Both
TcIL3000_5_4970 dihydrolipoamide branched chain transacylase,	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_009880 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_009880	Both
TcIL3000_9_5290 ⚠ Leucine carboxyl methyltransferase/Cupin-like	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_005852 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_005852	Both
TcIL3000_5_640 ⚠ NADH-dependent fumarate reductase	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_005116 OG6 TCSYLVIO_003428 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_003428 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_005116 +2 more	Both
TcIL3000_0_26130 ⚠ Histidine kinase-, DNA gyrase B-, and HSP90-l	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_003428 ↔ TCSYLVIO_009400 OG6 TCSYLVIO_003428 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_008621 +2 more	Both
TcIL3000_0_26140 ⚠ Heat shock protein 83, putative	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_008621 OG6 TCSYLVIO_003428 ↔ TCSYLVIO_009400 OG6 TCSYLVIO_003428 ↔ TCSYLVIO_009151 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_008621 +2 more	Both
TcIL3000_10_12750 ⚠ C-terminal motor kinesin, putative (fragment)	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_006065	OG6
TcIL3000_0_41040 ⚠ leucine carboxyl methyltransferase, putative	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_005852 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_005852	Both
TcIL3000_7_5700 ⚠ zinc-finger of a C2HC-type, putative	—	OG7 TCSYLVIO_003428 ↔ TCSYLVIO_006138	OG7
TcIL3000_10_590 ATP synthase, putative	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_009332 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_009332	Both
TcIL3000_10_11660 hypothetical protein, conserved	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_006181 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_006181	Both
TcIL3000.11.2830 ⚠ ribosome assembly protein RRB1, putative	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_005619 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_005619	Both
TcIL3000_10_13860 ⚠ zinc-finger of a C2HC-type/Double zinc ribbon	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_006138 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_006138	Both
TcIL3000_4_2130 ⚠ asparaginyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_003867 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_003428 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_003867	Both
TcIL3000_9_2550 ⚠ hypothetical protein	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_007342	OG6
TcIL3000_0_54930 ⚠ cysteine peptidase, Clan CA, family C2, putat	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_007342	OG6
TcIL3000_0_13010 ⚠ WD domain, G-beta repeat, putative	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_010560 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_010560	Both
TcIL3000_4_2090 hypothetical protein, conserved	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_003865 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_003865	Both
TcIL3000_10_2340 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_004376 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_004376	Both
TcIL3000_9_760 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_003586 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_003586	Both
TcIL3000_10_2980 ⚠ NADH-dependent fumarate reductase	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_005116 OG6 TCSYLVIO_003428 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_003428 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_005116 +2 more	Both
TcIL3000_9_2560 ⚠ cysteine peptidase, Clan CA, family C2, putat	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_007342	OG6
TcIL3000_5_620 ⚠ NADH-dependent fumarate reductase (fragment)	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_005116 OG6 TCSYLVIO_003428 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_003428 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_005116 +2 more	Both
TcIL3000_0_35850 ⚠ ubiquitin ligase, putative (fragment)	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_006542 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_006542	Both
TcIL3000_0_22360 ⚠ NADH-dependent fumarate reductase	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_005116 OG6 TCSYLVIO_003428 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_003428 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_005116 +2 more	Both
TcIL3000.11.2160 phenylalanyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_005548 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_005548	Both

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