TcIL3000_0_41370

Poly(A)-specific ribonuclease PARN-1
Trypanosoma congolense IL3000 OG6: OG6_102215 OG7: OG7_0005534 210 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 210 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_8_6040 ⚠
tubulin folding cofactor D, putative
— Both
TcIL3000.11.2160 ⚠
phenylalanyl-tRNA synthetase, putative
— Both
TcIL3000_4_2130 ⚠
asparaginyl-tRNA synthetase, putative
— Both
TcIL3000_0_14610 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— +1 more Both
TcIL3000_0_50370 ⚠
tubulin folding cofactor D, putative (fragmen
— Both
TcIL3000_6_1480 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcIL3000_10_1050 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
TcIL3000_1_420 ⚠
developmentally regulated phosphoprotein, put
— Both
TcIL3000_0_28240 ⚠
cysteinyl-tRNA synthetase, putative
— Both
TcIL3000_4_420 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
TcIL3000_6_1350 ⚠
kinesin, putative
— OG6
TcIL3000_0_29030 ⚠
geranylgeranyl transferase type II beta subun
— OG7
TcIL3000_4_310 ⚠
geranylgeranyl transferase type II beta subun
— OG7
TcIL3000_2_1360 ⚠
tubulin-tyrosine ligase, putative
— OG7
TcIL3000_5_4350 ⚠
tubulin tyrosine ligase, putative
— OG7
TcIL3000.11.7400 ⚠
Domain of unknown function(DUF2779), putative
— OG7
TcIL3000_10_4750 ⚠
Fructose-bisphosphate aldolase class-I, putat
— OG7
TcIL3000_0_41520 ⚠
tubulin tyrosine ligase, putative (fragment)
— OG7
TcIL3000_0_00900 ⚠
RNA binding protein, putative
— OG7
TcIL3000.11.7370 ⚠
tubulin-tyrsoine ligase-like protein, putativ
— OG7
TcIL3000_0_10970 ⚠
Tubulin-tyrosine ligase family, putative (fra
— OG7
TcIL3000_10_4760 ⚠
fructose-bisphosphate aldolase, glycosomal, p
— OG7
TcIL3000_10_11810 ⚠
tubulin tyrosine ligase protein, putative
— OG7
TcIL3000_1_900 ⚠
tubulin-tyrosine ligase, putative
— OG7
TcIL3000_10_10900 ⚠
cholinephosphate cytidylyltransferase A, puta
— OG7
TcIL3000_3_880 ⚠
U6 snRNA-associated Sm-like protein LSm8p
— OG7
TcIL3000_9_1040 ⚠
U6 snRNA-associated Sm-like protein LSm6p, Sm
— OG7
TcIL3000.11.8840 ⚠
DIS3-like exonuclease, putative
— OG7
TcIL3000_9_2450 ⚠
exoribonuclease DSS-1 (EMBL:AY233297), putati
— OG7
TcIL3000_3_3060 ⚠
Ankyrin repeats (many copies)/Ankyrin repeats
— Both
TcIL3000.11.14420 ⚠
phenylalanyl-tRNA synthetase alpha chain, put
— Both
TcIL3000_9_4940 ⚠
hypothetical protein, conserved
— Both
TcIL3000_5_1030 ⚠
choline/ethanolamine kinase
— Both
TcIL3000_5_4970 ⚠
dihydrolipoamide branched chain transacylase,
— Both
TcIL3000_0_38820 ⚠
acidocalcisomal pyrophosphatase
— Both
TcIL3000_0_26120 ⚠
Hsp90 protein, putative (fragment)
— +2 more Both
TcIL3000_5_630 ⚠
NADH-dependent fumarate reductase
— Both
TcIL3000_5_1650 ⚠
ribonucleoprotein p18, mitochondrial precurso
— Both
TcIL3000_0_44870 ⚠
PFU (PLAA family ubiquitin binding), putative
— Both
TcIL3000.11.9820 ⚠
hypothetical protein, conserved
— Both
TcIL3000_5_620 ⚠
NADH-dependent fumarate reductase (fragment)
— Both
TcIL3000_0_35010 ⚠
metallo-peptidase, Clan MF, Family M17
— Both
TcIL3000_0_35850 ⚠
ubiquitin ligase, putative (fragment)
— Both
TcIL3000_10_3810 ⚠
predicted SET domain protein, hypothetical pr
— Both
TcIL3000_6_1570 ⚠
hypothetical protein, conserved
— Both
TcIL3000.11.7210 ⚠
hypothetical protein, conserved
— Both
TcIL3000_0_22360 ⚠
NADH-dependent fumarate reductase
— Both
TcIL3000_0_26140 ⚠
Heat shock protein 83, putative
— +2 more Both
TcIL3000_9_1440 ⚠
DNA-damage inducible protein DDI1-like protei
— Both
TcIL3000_10_7230 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.