TcIL3000_5_4350

tubulin tyrosine ligase, putative
Trypanosoma congolense IL3000 OG6: OG6_104876 OG7: OG7_0001164 174 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 174 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_0_02490 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_8_5720 ⚠
cullin, putative
— OG7
TcIL3000_8_5040 ⚠
cullin, putative
— OG7
TcIL3000_0_03330 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_4_480 ⚠
TPR-repeat-containing chaperone protein DNAJ,
— OG7
TcIL3000_10_4220 ⚠
chaperone protein DnaJ, putative
— OG7
TcIL3000_0_40370 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
TcIL3000_1_1760 ⚠
chaperone protein DnaJ, putative
— OG7
TcIL3000_0_51360 ⚠
RNA polymerase beta subunit/RNA polymerase Rp
— OG7
TcIL3000_0_32940 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
TcIL3000_0_29100 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
TcIL3000_2_140 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcIL3000_0_23640 ⚠
C2H2 type zinc-finger (2 copies), putative
— OG7
TcIL3000_0_33580 ⚠
WD40 repeats, putative (fragment)
— OG7
TcIL3000_0_31210 ⚠
DnaJ domain containing protein, putative
— OG7
TcIL3000_8_7820 ⚠
dihydrouridine synthase (Dus), putative
— OG7
TcIL3000_4_4270 ⚠
RNA polymerase IIA largest subunit, putative
— OG7
TcIL3000_10_5200 ⚠
neurobeachin/beige protein, putative
— OG7
TcIL3000_2_150 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcIL3000_8_6400 ⚠
SpoU rRNA Methylase family, putative
— OG7
TcIL3000_6_4250 ⚠
DNA ligase I, putative (fragment)
— OG7
TcIL3000_10_4060 ⚠
tRNA-dihydrouridine synthase 2, putative
— OG7
TcIL3000_7_2940 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
TcIL3000_0_15840 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
TcIL3000_7_5350 ⚠
tRNA-dihydrouridine synthase 3, putative
— OG7
TcIL3000_10_2390 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
TcIL3000_10_4210 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
TcIL3000_10_10490 ⚠
cytosolic nonspecific dipeptidase, putative
— OG7
TcIL3000_8_4970 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_10_10600 ⚠
chaperone protein DnaJ, putative
— OG7
TcIL3000.11.9410 ⚠
DnaJ domain containing protein, putative
— OG7
TcIL3000_0_33050 ⚠
RNA polymerase IIA largest subunit, putative
— OG7
TcIL3000_1_120 ⚠
DNA-directed RNA polymerase III, putative
— OG7
TcIL3000_6_1530 ⚠
N-acetyltransferase B complex (NatB) non cata
— OG7
TcIL3000.11.9490 ⚠
Replication factor A protein 1
— OG7
TcIL3000_10_6450 ⚠
cullin, putative
— OG7
TcIL3000_2_530 ⚠
chaperone protein DnaJ, putative
— OG7
TcIL3000.11.14390 ⚠
polypyrimidine tract-binding protein, putativ
— OG7
TcIL3000_8_2480 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
TcIL3000_0_55160 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
TcIL3000_4_110 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
TcIL3000_7_4310 ⚠
SpoU rRNA Methylase family, putative
— OG7
TcIL3000_4_4310 ⚠
dihydrolipoamide dehydrogenase, point mutatio
— OG7
TcIL3000_0_36120 ⚠
neurobeachin/beige protein, putative
— OG7
TcIL3000_0_52930 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
TcIL3000_4_2920 ⚠
tRNA-dihydrouridine synthase 4, putative
— OG7
TcIL3000_0_48840 ⚠
neurobeachin/beige protein, putative
— OG7
TcIL3000_0_00730 ⚠
neurobeachin/beige protein, putative (fragmen
— OG7
TcIL3000_0_25380 ⚠
tyrosyl-DNA Phosphodiesterase (Tdp1), putativ
— OG7
TcIL3000_7_4940 ⚠
mercaptopyruvate sulfurtransferase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.