TcIL3000_8_2480

ubiquitin-activating enzyme E1, putative
Trypanosoma congolense IL3000 OG6: OG6_100444 OG7: OG7_0003530 177 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 177 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_0_04870 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcIL3000_0_31970 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcIL3000_0_55150 ⚠
ubiquitin-protein ligase, putative (fragment)
— OG7
TcIL3000_9_5740 ⚠
Importin 1 (fragment)
— Both
TcIL3000_6_1070 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— Both
TcIL3000_0_16560 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— Both
TcIL3000_3_1630 ⚠
Ubiquitin-like domain containing protein, put
— Both
TcIL3000_1_900 ⚠
tubulin-tyrosine ligase, putative
— Both
TcIL3000_9_5780 ⚠
hypothetical protein, conserved
— Both
TcIL3000.11.12390 ⚠
MRP protein, putative
— OG6
TcIL3000_7_1010 ⚠
nucleotide binding protein, putative
— Both
TcIL3000_10_1430 ⚠
nucleotide binding protein, putative
— Both
TcIL3000_0_26440 ⚠
hypothetical protein, conserved
— Both
TcIL3000_8_5510 ⚠
Met-10+ like-protein, putative
— Both
TcIL3000_2_220 ⚠
casein kinase II, alpha chain
— OG6
TcIL3000_10_9180 ⚠
ATP-binding cassette sub-family F member 1, p
— Both
TcIL3000_10_3050 ⚠
proteasome activator protein pa26, putative
— Both
TcIL3000_10_1000 ⚠
Programmed cell death protein 2, C-terminal p
— Both
TcIL3000_7_2330 ⚠
Beta-lactamase superfamily domain containing
— Both
TcIL3000_8_3320 ⚠
Beta-lactamase superfamily domain containing
— Both
TcIL3000_3_1210 ⚠
Xaa-Pro aminopeptidase, putative
— Both
TcIL3000_3_1610 ⚠
TatD related DNase, putative
— Both
TcIL3000_10_8960 ⚠
iron-containing hydrogenase, putative
— Both
TcIL3000.11.16260 ⚠
Importin-beta N-terminal domain containing pr
— OG7
TcIL3000_0_38880 ⚠
Importin-beta N-terminal domain containing pr
— OG7
TcIL3000.11.16240 ⚠
Importin-beta N-terminal domain/HEAT-like rep
— OG7
TcIL3000.11.16250 ⚠
HEAT-like repeat, putative
— OG7
TcIL3000_0_22460 ⚠
oxidoreductase, putative (fragment)
— OG7
TcIL3000_0_19090 ⚠
hypothetical protein
— OG7
TcIL3000_0_14160 ⚠
dihydrouridine synthase (Dus), putative (frag
— OG7
TcIL3000_3_1550 ⚠
hypothetical protein
— OG7
TcIL3000_6_3140 ⚠
hypothetical protein, conserved
— OG7
TcIL3000.11.14090 ⚠
U5 small nuclear ribonucleoprotein component,
— OG7
TcIL3000_0_33580 ⚠
WD40 repeats, putative (fragment)
— OG7
TcIL3000_10_4060 ⚠
tRNA-dihydrouridine synthase 2, putative
— OG7
TcIL3000_7_5760 ⚠
mitochondrial glycoprotein-like protein, puta
— OG7
TcIL3000.11.14630 ⚠
Zinc finger, ZZ type, putative
— OG7
TcIL3000_7_5350 ⚠
tRNA-dihydrouridine synthase 3, putative
— OG7
TcIL3000_10_8600 ⚠
ubiquitin-protein ligase, putative
— OG7
TcIL3000_3_2470 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_26670 ⚠
p22 protein precursor, putative
— OG7
TcIL3000_0_02840 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_3_1560 ⚠
ATP-dependent DEAD/H RNA helicase, putative (
— OG7
TcIL3000_10_9050 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
TcIL3000_5_4340 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
TcIL3000_0_26010 ⚠
ADP-ribosylation factor GTPase activating pro
— OG7
TcIL3000_9_1710 ⚠
glutaminyl-tRNA synthetase, putative
— OG7
TcIL3000_3_3280 ⚠
centaurin beta 5, ADP-ribosylation factor GTP
— OG7
TcIL3000_0_03350 ⚠
tubulin gamma chain
— OG7
TcIL3000_9_6580 ⚠
ADP-ribosylation factor GTPase activating pro
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.