TcIL3000.11.16240

Importin-beta N-terminal domain/HEAT-like repeat, putative
Trypanosoma congolense IL3000 OG6: OG6_102877 OG7: OG7_0003452 97 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 97 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_0_36120 ⚠
neurobeachin/beige protein, putative
— OG7
TcIL3000_9_5740 ⚠
Importin 1 (fragment)
— OG7
TcIL3000_10_3700 ⚠
cap guanine-N7 methyltransferase
— OG7
TcIL3000.11.3980 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_10_12710 ⚠
Hydroxyneurosporene synthase (CrtC)/Polypreny
— OG7
TcIL3000_8_5980 ⚠
Galactose oxidase, central domain/Kelch motif
— OG7
TcIL3000_10_13380 ⚠
FKBP-type peptidylprolyl cis-trans isomerase,
— OG7
TcIL3000_10_3830 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcIL3000_5_4560 ⚠
U6 snRNA-associated Sm-like protein LSm7p, pu
— OG7
TcIL3000_0_26440 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_9_5750 ⚠
hypothetical protein (fragment)
— OG7
TcIL3000_10_7430 ⚠
Galactose oxidase, central domain containing
— OG7
TcIL3000.11.10800 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
TcIL3000_3_1560 ⚠
ATP-dependent DEAD/H RNA helicase, putative (
— OG7
TcIL3000_3_880 ⚠
U6 snRNA-associated Sm-like protein LSm8p
— OG7
TcIL3000_0_55160 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
TcIL3000_8_2480 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
TcIL3000_0_22030 ⚠
Galactose oxidase, central domain containing
— OG7
TcIL3000_10_4920 ⚠
Galactose oxidase, central domain containing
— OG7
TcIL3000_0_03850 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
TcIL3000.11.9770 ⚠
Galactose oxidase, central domain containing
— OG7
TcIL3000_10_13370 ⚠
macrophage infectivity potentiator, precursor
— OG7
TcIL3000_10_6410 ⚠
ATP-dependent DEAD/H RNA helicase, putative,
— OG7
TcIL3000_0_42730 ⚠
Beige/BEACH domain containing protein, putati
— OG7
TcIL3000_4_1500 ⚠
Carboxypeptidase-like protein
— OG7
TcIL3000.11.2280 ⚠
metallo-peptidase, Clan MF, Family M17 (fragm
— OG7
TcIL3000_3_750 ⚠
WD domain, G-beta repeat, putative (fragment)
— OG7
TcIL3000_3_230 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
TcIL3000_0_16560 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— OG7
TcIL3000_6_1070 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— OG7
TcIL3000_0_01600 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
TcIL3000_5_110 ⚠
methyltransferase, putative
— OG7
TcIL3000_3_340 ⚠
GTP-binding nuclear protein rtb2, putative
— OG7
TcIL3000_10_3760 ⚠
elongation factor 2, putative
— OG7
TcIL3000_3_1280 ⚠
translation elongation factor EF-2, putative
— OG7
TcIL3000.11.14090 ⚠
U5 small nuclear ribonucleoprotein component,
— OG7
TcIL3000.11.3970 ⚠
BTB/POZ domain/Galactose oxidase, central dom
— OG7
TcIL3000_5_4430 ⚠
Galactose oxidase, central domain/Domain of u
— OG7
TcIL3000_0_48840 ⚠
neurobeachin/beige protein, putative
— OG7
TcIL3000_0_05260 ⚠
heat shock protein HslVU, ATPase subunit HslU
— OG7
TcIL3000_0_00730 ⚠
neurobeachin/beige protein, putative (fragmen
— OG7
TcIL3000_0_01620 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
TcIL3000_7_1370 ⚠
NF-X1 type zinc finger/R3H domain containing
— OG7
TcIL3000_1_320 ⚠
kelch domain-containing protein
— OG7
TcIL3000_10_9050 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
TcIL3000_10_5210 ⚠
neurobeachin/beige protein, putative (fragmen
— OG7
TcIL3000_10_7700 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_7_2670 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcIL3000_9_1040 ⚠
U6 snRNA-associated Sm-like protein LSm6p, Sm
— OG7
TcIL3000_7_3200 ⚠
Eukaryotic glutathione synthase, ATP binding
— Both
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.