TcIL3000_1_320

kelch domain-containing protein
Trypanosoma congolense IL3000 OG6: OG6_114707 OG7: OG7_0001012 138 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 138 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_2_1630 ⚠
chaperone protein ClpB1, putative
— OG7
TcIL3000_2_370 ⚠
serine peptidase, putative, ATP-dependent Clp
— OG7
TcIL3000_2_1650 ⚠
chaperone protein ClpB1, putative
— OG7
TcIL3000_0_29890 ⚠
inositol-1(or 4)-monophosphatase, putative (f
— OG7
TcIL3000.11.3370 ⚠
hypothetical protein, conserved
— OG7
TcIL3000.11.15170 ⚠
coatomer subunit epsilon
— OG7
TcIL3000.11.7640 ⚠
proteasome alpha 7 subunit, putative
— OG7
TcIL3000_10_7230 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
TcIL3000_9_1710 ⚠
glutaminyl-tRNA synthetase, putative
— OG7
TcIL3000_10_13320 ⚠
ABC transporter, putative
— OG7
TcIL3000_10_6290 ⚠
terminal uridylyltransferase 3, putative
— OG7
TcIL3000_9_2190 ⚠
inositol-1(or 4)-monophosphatase, putative
— OG7
TcIL3000_10_9180 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
TcIL3000_0_46520 ⚠
RNA-editing complex protein
— OG7
TcIL3000_3_920 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcIL3000_0_53530 ⚠
tRNA synthetases class I (E and Q), anti-codo
— OG7
TcIL3000_0_57900 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcIL3000_9_3500 ⚠
proteasome alpha 1 subunit, putative, 20S pro
— OG7
TcIL3000_3_150 ⚠
proteasome alpha 7 subunit, putative
— OG7
TcIL3000_0_38710 ⚠
ubiquitin-protein ligase, putative
— OG7
TcIL3000.11.14090 ⚠
U5 small nuclear ribonucleoprotein component,
— OG7
TcIL3000_4_2250 ⚠
Glycosyl hydrolase family 65 central catalyti
— OG7
TcIL3000_0_30090 ⚠
glutamyl-tRNA synthetase, putative (fragment)
— OG7
TcIL3000_0_32360 ⚠
Midasin, putative (fragment)
— OG7
TcIL3000_10_7240 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
TcIL3000_8_2060 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_10_90 ⚠
proteasome subunit alpha type-5, putative
— OG7
TcIL3000_8_5130 ⚠
WW domain containing protein, putative
— OG7
TcIL3000_0_00160 ⚠
kinetoplast poly(A) polymerase 1
— OG7
TcIL3000_3_1280 ⚠
translation elongation factor EF-2, putative
— OG7
TcIL3000_0_25030 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_5_2780 ⚠
inositol-1(or 4)-monophosphatase 1, putative
— OG7
TcIL3000_10_8540 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
TcIL3000_10_5090 ⚠
proteasome subunit alpha type-1, putative
— OG7
TcIL3000_6_4040 ⚠
glutamyl-tRNA synthetase, putative
— OG7
TcIL3000_6_4210 ⚠
hypothetical protein, conserved
— OG7
TcIL3000.11.16920 ⚠
leucine-rich repeat protein (LRRP), putative
— OG7
TcIL3000_10_3760 ⚠
elongation factor 2, putative
— OG7
TcIL3000_0_55120 ⚠
hypothetical protein
— OG7
TcIL3000_0_11960 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
TcIL3000_4_3080 ⚠
myosin IB heavy chain, putative
— OG7
TcIL3000_10_2630 ⚠
ABC transporter, putative
— OG7
TcIL3000.11.8500 ⚠
kinetoplast poly(A) polymerase 1
— OG7
TcIL3000_0_07020 ⚠
glycosyl hydrolase, putative (fragment)
— OG7
TcIL3000.11.2610 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_10_150 ⚠
proteasome alpha 2 subunit, putative
— OG7
TcIL3000_9_5900 ⚠
proteasome complex subunit Rpn13 ubiquitin re
— OG7
TcIL3000.11.16100 ⚠
ATP binding protein-like protein
— OG7
TcIL3000_2_1050 ⚠
thioredoxin, putative
— OG7
TcIL3000_9_6220 ⚠
proteasome complex subunit Rpn13 ubiquitin re
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.