TcIL3000_3_230

NAD binding domain of 6-phosphogluconate dehydrogenase/NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase, putative
Trypanosoma congolense IL3000 OG6: OG6_147095 OG7: OG7_0002731 201 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 201 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_0_50890 ⚠
UBA/TS-N domain containing protein, putative
— OG7
TcIL3000_10_4160 ⚠
ubiquitin-like protein DSK2, putative
— OG7
TcIL3000_7_1560 ⚠
carnitine O-palmitoyltransferase II, putative
— OG7
TcIL3000_10_9180 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
TcIL3000_3_1550 ⚠
hypothetical protein
— OG7
TcIL3000_0_54180 ⚠
hypothetical protein (fragment)
— OG7
TcIL3000_10_13320 ⚠
ABC transporter, putative
— OG7
TcIL3000_9_5780 ⚠
hypothetical protein, conserved
— OG7
TcIL3000.11.16260 ⚠
Importin-beta N-terminal domain containing pr
— OG7
TcIL3000.11.9190 ⚠
tRNA threonylcarbamoyl adenosine modification
— OG7
TcIL3000.11.14520 ⚠
ubiquitin-conjugating enzyme E2, putative
— OG7
TcIL3000_0_12320 ⚠
carnitine O-palmitoyltransferase II, putative
— OG7
TcIL3000_3_520 ⚠
NPL4 family, putative
— OG7
TcIL3000_10_12130 ⚠
N-myristoyl transferase, putative
— OG7
TcIL3000_0_17750 ⚠
Mitochondrial Editosome-like Complex TUTase
— OG7
TcIL3000_5_4770 ⚠
hypothetical protein, conserved
— OG7
TcIL3000.11.15410 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_58030 ⚠
cyclin 1
— OG7
TcIL3000_9_750 ⚠
deoxyhypusine hydroxylase, putative
— OG7
TcIL3000.11.9290 ⚠
Elongation factor G 2, mitochondrial, putativ
— OG7
TcIL3000_0_43620 ⚠
isocitrate dehydrogenase, putative
— OG7
TcIL3000_10_6800 ⚠
Metalloenzyme superfamily, putative (fragment
— OG7
TcIL3000.11.12420 ⚠
Eukaryotic translation initiation factor 4E-3
— OG7
TcIL3000.11.10360 ⚠
Protein of unknown function (DUF2009), putati
— OG7
TcIL3000.11.16400 ⚠
enoyl-CoA hydratase/isomerase family protein,
— OG7
TcIL3000_0_27080 ⚠
6-phosphogluconolactonase
— OG7
TcIL3000_3_1620 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_4_370 ⚠
AP-1 adapter complex gamma subunit, putative
— OG7
TcIL3000.11.13190 ⚠
cyclin 1
— OG7
TcIL3000_10_30 ⚠
Kinetoplast poly(A) polymerase 2
— OG7
TcIL3000_0_04800 ⚠
carnitine O-palmitoyltransferase II, putative
— OG7
TcIL3000_6_1750 ⚠
pdz domain containing protein, putative (frag
— OG7
TcIL3000_3_1810 ⚠
eukaryotic translation initiation factor 2 su
— OG7
TcIL3000.11.10550 ⚠
Biotin--acetyl-CoA-carboxylase ligase, putati
— OG7
TcIL3000_1_790 ⚠
Mitochondrial Editosome-like Complex TUTase
— OG7
TcIL3000.11.15680 ⚠
poly(A) polymerase, putative
— OG7
TcIL3000_10_12020 ⚠
pyruvate kinase 1, putative
— OG7
TcIL3000_9_4310 ⚠
Protein of unknown function (DUF2009), putati
— OG7
TcIL3000_0_07850 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
TcIL3000_10_4190 ⚠
Elongation factor G1, mitochondrial, putative
— OG7
TcIL3000_3_2510 ⚠
carnitine O-palmitoyltransferase II, putative
— OG7
TcIL3000_10_11950 ⚠
Activator of Hsp90 ATPase, N-terminal/Activat
— OG7
TcIL3000_10_4450 ⚠
eukaryotic translation initiation factor 6, p
— OG7
TcIL3000.11.7660 ⚠
acidocalcisomal pyrophosphatase
— OG7
TcIL3000_9_350 ⚠
Zn-finger in Ran binding protein and others/S
— OG7
TcIL3000_0_42430 ⚠
Flagellum attachment zone protein 19, putativ
— OG7
TcIL3000_0_38820 ⚠
acidocalcisomal pyrophosphatase
— OG7
TcIL3000_9_4810 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
TcIL3000_10_9010 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_6_1860 ⚠
adenosine kinase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.