TcIL3000_0_07850

Eukaryotic translation initiation factor 4E-1
Trypanosoma congolense IL3000 OG6: OG6_100627 OG7: OG7_0002303 239 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 239 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_0_47000 ⚠
IQ calmodulin-binding motif containing protei
— OG7
TcIL3000_0_21580 ⚠
haloacid dehalogenase hydrolase, putative
— OG7
TcIL3000.11.7950 ⚠
haloacid dehalogenase hydrolase, putative
— OG7
TcIL3000_0_41270 ⚠
Vps51/Vps67, putative (fragment)
— OG7
TcIL3000_2_190 ⚠
Vps51/Vps67, putative (fragment)
— OG7
TcIL3000_7_1560 ⚠
carnitine O-palmitoyltransferase II, putative
— OG7
TcIL3000_0_04800 ⚠
carnitine O-palmitoyltransferase II, putative
— OG7
TcIL3000.11.1940 ⚠
carnitine O-acetyltransferase, putative
— OG7
TcIL3000_0_37080 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_35980 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_48840 ⚠
neurobeachin/beige protein, putative
— OG7
TcIL3000_9_3550 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_6_1570 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_00730 ⚠
neurobeachin/beige protein, putative (fragmen
— OG7
TcIL3000_0_01620 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
TcIL3000_0_03380 ⚠
Protein of unknown function (DUF3808), putati
— OG7
TcIL3000_10_2400 ⚠
Conserved oligomeric complex COG6, putative
— OG7
TcIL3000_10_5210 ⚠
neurobeachin/beige protein, putative (fragmen
— OG7
TcIL3000_10_5220 ⚠
Sec34-like family, putative
— OG7
TcIL3000_0_17950 ⚠
phosphatidylethanolamine-binding protein, put
— OG7
TcIL3000_0_19740 ⚠
Protein of unknown function (DUF3808), putati
— OG7
TcIL3000_0_37380 ⚠
hypothetical protein (fragment)
— OG7
TcIL3000_0_41150 ⚠
conserved protein
— OG7
TcIL3000_10_1050 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
TcIL3000.11.11250 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_41310 ⚠
Vps23 core domain containing protein, putativ
— OG7
TcIL3000_0_36120 ⚠
neurobeachin/beige protein, putative
— OG7
TcIL3000_2_490 ⚠
translation initiation factor IF-2, putative
— OG7
TcIL3000_4_2130 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
TcIL3000_0_42730 ⚠
Beige/BEACH domain containing protein, putati
— OG7
TcIL3000_8_600 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
TcIL3000_6_3350 ⚠
replication factor C, subunit 2, putative
— OG7
TcIL3000_9_5080 ⚠
replication factor C, subunit 3, putative (fr
— OG7
TcIL3000_10_7230 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
TcIL3000_0_38710 ⚠
ubiquitin-protein ligase, putative
— OG7
TcIL3000_10_7240 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
TcIL3000_8_5130 ⚠
WW domain containing protein, putative
— OG7
TcIL3000_6_1870 ⚠
ubiquitin-protein ligase, putative
— OG7
TcIL3000_0_55120 ⚠
hypothetical protein
— OG7
TcIL3000_0_11960 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
TcIL3000_0_25450 ⚠
SPRY domain containing protein, putative (fra
— OG7
TcIL3000_8_1450 ⚠
ubiquitin-protein ligase, putative
— OG7
TcIL3000_6_2060 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcIL3000_2_1280 ⚠
aldo-keto reductase, putative
— OG7
TcIL3000_0_14620 ⚠
clathrin coat assembly protein, putative
— OG7
TcIL3000.11.2880 ⚠
IQ calmodulin-binding motif containing protei
— OG7
TcIL3000_0_07290 ⚠
paraflagellar rod component, putative
— OG7
TcIL3000_0_19750 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_6_1480 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcIL3000_10_5200 ⚠
neurobeachin/beige protein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.