TcIL3000.11.12420

Eukaryotic translation initiation factor 4E-3
Trypanosoma congolense IL3000 OG6: OG6_134811 OG7: OG7_0002303 226 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 226 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_8_4880 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_5_3620 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_8_5400 ⚠
dihydroorotase, putative
— OG7
TcIL3000_7_3030 ⚠
Bifunctional NAD(P)H-hydrate repair enzyme
— OG7
TcIL3000_4_4000 ⚠
diphthine synthase, putative
— OG7
TcIL3000_0_13010 ⚠
WD domain, G-beta repeat, putative
— OG7
TcIL3000_0_21000 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcIL3000_0_30110 ⚠
WD domain, G-beta repeat, putative
— OG7
TcIL3000_10_4160 ⚠
ubiquitin-like protein DSK2, putative
— OG7
TcIL3000_0_50890 ⚠
UBA/TS-N domain containing protein, putative
— OG7
TcIL3000_0_57530 ⚠
hypothetical protein
— OG7
TcIL3000_0_24870 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_5_1680 ⚠
Ecotin-like protein
— OG7
TcIL3000_0_25700 ⚠
inhibitor of serine peptidase (ISP), putative
— OG7
TcIL3000_0_08210 ⚠
ecotin, putative
— OG7
TcIL3000_0_08890 ⚠
inhibitor of serine peptidase (ISP), putative
— OG7
TcIL3000.11.2160 ⚠
phenylalanyl-tRNA synthetase, putative
— OG7
TcIL3000_3_1560 ⚠
ATP-dependent DEAD/H RNA helicase, putative (
— OG7
TcIL3000_10_6410 ⚠
ATP-dependent DEAD/H RNA helicase, putative,
— OG7
TcIL3000_3_1550 ⚠
hypothetical protein
— OG7
TcIL3000.11.9360 ⚠
p21-C-terminal region-binding protein, putati
— OG7
TcIL3000_7_370 ⚠
hypothetical protein, conserved
— OG7
TcIL3000.11.14340 ⚠
Outer row dynein-assembly protein 7
— OG7
TcIL3000.11.11760 ⚠
Leucine Rich repeats (2 copies), putative
— OG7
TcIL3000_7_2270 ⚠
small nuclear ribonucleoprotein SmD1, SmD-1 l
— OG7
TcIL3000_8_360 ⚠
Domain of unknown function (DUF3437), putativ
— OG7
TcIL3000_10_9800 ⚠
nicotinate phosphoribosyltransferase, putativ
— OG7
TcIL3000_10_6600 ⚠
protein transport protein Sec23A, putative
— OG7
TcIL3000_8_3580 ⚠
protein transport protein SEC23
— OG7
TcIL3000_3_3580 ⚠
nuclear transcription factor, putative
— OG7
TcIL3000_0_01600 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
TcIL3000.11.4300 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_42510 ⚠
aspartyl aminopeptidase, putative
— OG7
TcIL3000_10_8500 ⚠
Protein of unknown function (DUF2870), putati
— OG7
TcIL3000_8_4690 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_55050 ⚠
GMP synthase [glutamine-hydrolysing]
— OG7
TcIL3000_0_27490 ⚠
GMP synthase, putative (fragment)
— OG7
TcIL3000_6_1070 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— OG7
TcIL3000_3_1740 ⚠
inorganic pyrophosphatase, putative
— OG7
TcIL3000_0_16560 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— OG7
TcIL3000_3_230 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
TcIL3000_0_38820 ⚠
acidocalcisomal pyrophosphatase
— OG7
TcIL3000.11.7660 ⚠
acidocalcisomal pyrophosphatase
— OG7
TcIL3000_0_42430 ⚠
Flagellum attachment zone protein 19, putativ
— OG7
TcIL3000_3_3310 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_53680 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_12430 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_9_750 ⚠
deoxyhypusine hydroxylase, putative
— OG7
TcIL3000_0_27090 ⚠
PUB domain containing protein, putative (frag
— OG7
TcIL3000.11.6900 ⚠
PUB domain containing protein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.