TcIL3000_10_9800

nicotinate phosphoribosyltransferase, putative
Trypanosoma congolense IL3000 OG6: OG6_109462 OG7: OG7_0015320 170 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 170 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000.11.3100 ⚠
Kinesin-13 5, putative
— OG7
TcIL3000_0_13760 ⚠
hypothetical protein (fragment)
— Both
TcIL3000_9_3590
peptidyl-prolyl cis-trans isomerase (cyclophi
— OG6
TcIL3000_5_2610 ⚠
Macro domain containing protein, putative
— Both
TcIL3000_8_3630 ⚠
Mitogen-activated protein kinase 10, putative
— OG6
TcIL3000_10_4450
eukaryotic translation initiation factor 6, p
— Both
TcIL3000_10_11950
Activator of Hsp90 ATPase, N-terminal/Activat
— Both
TcIL3000.11.15220 ⚠
iron superoxide dismutase
— Both
TcIL3000_0_27080 ⚠
6-phosphogluconolactonase
— Both
TcIL3000.11.16400
enoyl-CoA hydratase/isomerase family protein,
— Both
TcIL3000.11.10360 ⚠
Protein of unknown function (DUF2009), putati
— Both
TcIL3000_10_1910
hypothetical protein, conserved
— Both
TcIL3000.11.1580 ⚠
Serine-threonine kinase receptor-associated p
— Both
TcIL3000_0_43620 ⚠
isocitrate dehydrogenase, putative
— Both
TcIL3000_8_3490
mitogen-activated protein kinase 3, putative
— OG6
TcIL3000_6_260
dephospho-CoA kinase, putative
— OG6
TcIL3000_0_47240 ⚠
monothiol glutaredoxin, putative
— Both
TcIL3000.11.15750 ⚠
superoxide dismutase, putative
— Both
TcIL3000_0_17750 ⚠
Mitochondrial Editosome-like Complex TUTase
— Both
TcIL3000_5_4770 ⚠
hypothetical protein, conserved
— Both
TcIL3000_3_520
NPL4 family, putative
— Both
TcIL3000_10_12130
N-myristoyl transferase, putative
— Both
TcIL3000_5_680 ⚠
monothiol glutaredoxin, putative
— Both
TcIL3000_1_790 ⚠
Mitochondrial Editosome-like Complex TUTase
— Both
TcIL3000.11.10550 ⚠
Biotin--acetyl-CoA-carboxylase ligase, putati
— Both
TcIL3000_9_4310 ⚠
Protein of unknown function (DUF2009), putati
— Both
TcIL3000_10_12020
pyruvate kinase 1, putative
— Both
TcIL3000_0_07850 ⚠
Eukaryotic translation initiation factor 4E-1
— Both
TcIL3000_5_2540 ⚠
Macro domain containing protein, putative
— Both
TcIL3000_8_2120
hypothetical protein, conserved
— Both
TcIL3000_10_4190 ⚠
Elongation factor G1, mitochondrial, putative
— Both
TcIL3000_9_350 ⚠
Zn-finger in Ran binding protein and others/S
— Both
TcIL3000_9_1010
cyclophilin type peptidyl-prolyl cis-trans is
— OG6
TcIL3000_0_45620
hypothetical protein, conserved
— Both
TcIL3000_0_44700 ⚠
transcription elongation factor s-II, putativ
— Both
TcIL3000_0_50720 ⚠
PWWP domain/TFIIS helical bundle-like domain
— Both
TcIL3000_0_22500
hypothetical protein, conserved
— Both
TcIL3000_3_1740 ⚠
inorganic pyrophosphatase, putative
— Both
TcIL3000_0_38820 ⚠
acidocalcisomal pyrophosphatase
— Both
TcIL3000.11.7660 ⚠
acidocalcisomal pyrophosphatase
— Both
TcIL3000_2_1100
esterase, putative
— Both
TcIL3000_0_49160 ⚠
mitotic centromere-associated kinesin, putati
— OG7
TcIL3000_0_33830 ⚠
mitotic centromere-associated kinesin, putati
— OG7
TcIL3000_0_03820 ⚠
Eukaryotic translation initiation factor 4E-2
— OG7
TcIL3000_10_30 ⚠
Kinetoplast poly(A) polymerase 2
— OG7
TcIL3000_0_20520 ⚠
eukaryotic translation initiation factor 3 su
— OG7
TcIL3000_7_3050 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_10_11620 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
TcIL3000_7_1320 ⚠
zinc finger protein, putative
— OG7
TcIL3000.11.15970 ⚠
zinc finger protein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.